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Epigenetics affects whether or not stem cells differentiate

Adult stem cells and progenitor cells may not come with a clean genetic slate after all. That's because a new report in the FASEB Journal shows that adult stem or progenitor cells have their own unique "epigenetic signatures," which change once a cell differentiates. This is important because epigenetic changes do not affect the actual make up in a cell's DNA, but rather, how that DNA functions.

1 Jul 2011

First ever clinical study using Brainwave Optimization technology to treat insomnia

Insomnia is the most prevalent sleep disorder, affecting up to 50 percent of the adult population in the United States on a weekly basis.

1 Jul 2011

Ovarian cancer molecular updates

In a new study a genetic mutation was found in the most common form of ovarian cancer. This according to the US scientists could pave the way for a more effective treatment of the disease. The detailed genetic map already helped scientists identify existing drugs with the potential for treating the mutations found in ovarian cancer tumors and also identified mutations that could respond to new drugs.

1 Jul 2011

Lantheus commences flurpiridaz F 18 PET MPI Phase 3 trial for detection of coronary artery disease

Lantheus Medical Imaging, Inc., a worldwide leader in diagnostic imaging, today announced the initiation of the first of two Phase 3 clinical trials to assess myocardial perfusion using Positron Emission Tomography (PET) imaging with flurpiridaz F 18 in patients with suspected or known coronary artery disease (CAD).

1 Jul 2011

Fast track protocol reduces hospital costs and infections in total hip replacement surgery

Generally healthy patients who undergo total hip replacement (THR) can be fast tracked to be discharged in two days compared with the standard three to six days, according to a new study by researchers at Hospital for Special Surgery (HSS) in New York City. The study could help cut down on hospital-acquired infections, reduce hospital costs and improve patient satisfaction.

1 Jul 2011

NIH awards Allina $2.4M grant to examine impact of integrative therapies for pain management

The National Institutes of Health has awarded $2.4 million to Allina Hospitals & Clinics to study the impact of integrative and mind/body therapies on pain management for patients at Abbott Northwestern Hospital in Minneapolis, Minn.

1 Jul 2011

Nicotine receptors play crucial role in social interaction

If you think nicotine receptors are only important to smokers trying to kick the tobacco habit, think again. New research published in the FASEB Journal (http://www.fasebj.org) suggests that these receptors also play an important role in social interaction and the ability to choose between competing motivations.

1 Jul 2011

Vitamin D-deficiency linked to deaths of famous musicians

Wolfgang Amadeus Mozart (27 January 1756 - 5 December 1791), suffered from many infectious illnesses including catarrh, fever, sore throat, and bad colds from 1762 to 1791, the year of his death at 35 years of age.

1 Jul 2011

Genetic variation associated with increased risk of sudden cardiac arrest

A study by a global consortium of physician-scientists has identified a genetic variation that may predispose people to double the risk of having a sudden cardiac arrest, a disorder that gives little warning and is fatal in about 95 percent of cases.

1 Jul 2011

Tranexamic acid effective for patients with head injury

New research has suggested that tranexamic acid has the potential to prevent people dying from head injuries.

1 Jul 2011

Study: Heart transplant patients more likely to get serious skin cancers

A new study published in the American Journal of Transplantation reveals that there is a significant risk of serious skin cancers, including cutaneous squamous cell carcinoma and melanoma, in heart transplant patients.

1 Jul 2011

Positive results from Nexavar Phase 2b trial on breast cancer presented at ASCO

Accelerated Community Oncology Research Network, Inc., reported positive results of a large double-blind, randomized Phase 2b trial in patients with breast cancer at the American Society of Clinical Oncology (ASCO) 47th annual meeting in Chicago, June 3-7.

1 Jul 2011

Positive topline results from Alkermes ALKS 9070 phase 1b study for schizophrenia

Alkermes, Inc. today announced positive topline results from a phase 1b, double-blind, randomized, placebo-controlled study of ALKS 9070 in patients with schizophrenia.

30 Jun 2011

Some generic anti-epilepsy drugs may not be effective

Generic anti-epilepsy drugs, pharmaceutical products similar to brand-name versions, save consumers billions of dollars each year, but some are different enough from branded formulations that they may not be effective, particularly if patients switch between two generic drugs, a new study by Johns Hopkins researchers suggests.

30 Jun 2011

Study confirms benefits of low-dose spiral CT scans for lung cancer detection

The New England Journal of Medicine's (NEJM) headline today read, "Reduced Lung Cancer Mortality with Low-Dose Computed Tomographic CT Screening," ending a long controversy over the use of an existing but underutilized early detection tool for those at risk for Lung Cancer. Preliminary results of the National Lung Screening Trial (NLST) were first released on November 4, 2010 and confirmed today.

30 Jun 2011

Auxilium reports three year data from XIAFLEX CORDLESS study in Dupuytren's contracture

Auxilium Pharmaceuticals, Inc., a specialty biopharmaceutical company, today announced three year recurrence data from the Collagenase Optimal Reduction of Dupuytren's - Long-term Evaluation of Success Study (CORDLESS) for XIAFLEX® (collagenase clostridium histolyticum) in the treatment of adult Dupuytren's contracture patients with a palpable cord.

30 Jun 2011

Chiropractors report high number of back-related injuries during summer moving period

Each year, chiropractors notice a recrudescence of patients that come for a consultation during the summer moving period. Not surprising when we know that many people, eager and tired, hasten to get everything done rapidly without worrying about their muscles and their back. That explains why herniated discs, lumbar pain and muscle soreness are so common during this time of year. How can we avoid this?

30 Jun 2011

PENNSAID Viscous Solution Phase 2 clinical trial for osteoarthritis pain meets primary endpoint

Nuvo Research Inc., a specialty pharmaceutical company dedicated to building a portfolio of products primarily for the treatment of pain, today announced receipt from Mallinckrodt Inc., a Covidien company (Covidien), of top-line results from a Phase 2 study conducted by Covidien, of twice-daily administration of PENNSAID Viscous Solution (topical diclofenac sodium viscous solution) 2% w/w, previously referred to as PENNSAID Gel.

30 Jun 2011

Lotus Tissue Repair to develop DEB protein replacement therapy with $26 million Series A financing

Lotus Tissue Repair, Inc. today announced the closing of a $26 million Series A financing led by Third Rock Ventures. Proceeds of the financing will be used to advance the company's proprietary recombinant collagen type VII (rC7) technology as the first and only protein replacement therapy in development for the treatment of dystrophic epidermolysis bullosa (DEB), an orphan disease that causes devastating skin blisters, morbidity and early mortality.

30 Jun 2011

Harvard University, UCB enter innovative research collaboration

UCB and Harvard University officially launched their innovative Research Alliance during a signing ceremony that took place in Boston last night in the presence of his Royal Highness Prince Philippe of Belgium.

30 Jun 2011

Medical Condition News

Epigenetics affects whether or not stem cells differentiate

First ever clinical study using Brainwave Optimization technology to treat insomnia

Ovarian cancer molecular updates

Lantheus commences flurpiridaz F 18 PET MPI Phase 3 trial for detection of coronary artery disease

Fast track protocol reduces hospital costs and infections in total hip replacement surgery

NIH awards Allina $2.4M grant to examine impact of integrative therapies for pain management

Nicotine receptors play crucial role in social interaction

Vitamin D-deficiency linked to deaths of famous musicians

Genetic variation associated with increased risk of sudden cardiac arrest

Tranexamic acid effective for patients with head injury

Study: Heart transplant patients more likely to get serious skin cancers

Positive results from Nexavar Phase 2b trial on breast cancer presented at ASCO

Positive topline results from Alkermes ALKS 9070 phase 1b study for schizophrenia

Some generic anti-epilepsy drugs may not be effective

Study confirms benefits of low-dose spiral CT scans for lung cancer detection

Auxilium reports three year data from XIAFLEX CORDLESS study in Dupuytren's contracture

Chiropractors report high number of back-related injuries during summer moving period

PENNSAID Viscous Solution Phase 2 clinical trial for osteoarthritis pain meets primary endpoint

Lotus Tissue Repair to develop DEB protein replacement therapy with $26 million Series A financing

Harvard University, UCB enter innovative research collaboration

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

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