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Curcumin compound can help head and neck cancer cells overcome resistance to chemotherapy drugs

A primary reason that head and neck cancer treatments fail is the tumor cells become resistant to chemotherapy drugs. Now, researchers at the University of Michigan Comprehensive Cancer Center have found that a compound derived from the Indian spice curcumin can help cells overcome that resistance.

20 May 2011

EMA CHMP issues positive opinion for marketing approval of BENLYSTA

GlaxoSmithKline and Human Genome Sciences, Inc. announced today that the European Medicines Agency's Committee for Medicinal Products for Human Use has issued a positive opinion, recommending marketing authorisation for BENLYSTA (belimumab) as an add-on therapy in adult patients with active autoantibody-positive systemic lupus erythematosus, with a high degree of disease activity, despite standard therapy.

20 May 2011

Meta-analysis confirms positive outcomes in patients implanted with Medtronic CoreValve System

A late-breaking presentation about transcatheter aortic valve implantation (TAVI) at EuroPCR 2011 today confirmed positive outcomes in patients receiving the CoreValve System from Medtronic, Inc. across seven international clinical registries.

From Medtronic 20 May 2011

Cholesterol drug may help treat mitochondrial diseases

A human drug that both prevents and cures kidney failure in mice sheds light on disabling human mitochondrial disorders, and may represent a potential treatment in people with such illnesses.

20 May 2011

Electrical disturbances in injured brain lead to poor recovery

Electrical disturbances that spread through an injured brain like tsunamis have a direct link to poor recovery and can last far longer than previously realized, researchers at the University of Cincinnati Neuroscience Institute have found.

20 May 2011

Surgeon's choices and choice of surgeons influence hospital charges for spinal fusion surgery

Hospital charges for spinal fusion surgery in the upper spine vary considerably—with the surgeon's choice of spinal hardware being the largest source of variation, reports a study in the May 15 issue of Spine.

20 May 2011

Osteoarthritis directly linked to low-fat, high-carb food

Osteoarthritis is a degenerative joint disease and the most common cause of disability today. It was once considered a problem of the old but it is now commonly diagnosed in those as young as the mid-twenties and early thirties. According to the Arthritis Foundation, about four million, quality-adjusted life years are lost due to knee osteoarthritis alone.

20 May 2011

RTOG reports on largest trial for newly diagnosed glioblastoma

RTOG reports on the largest trial to-date for patients with newly diagnosed glioblastoma demonstrating the importance and feasibility of prospective molecular analysis of tumor tissue although finding that patients received no additional benefit from dose-intensive temozolomide as compared to standard adjuvant temozolomide after combined temozolomide and radiotherapy.

20 May 2011

AMT presents long-term efficacy study of Glybera in treatment of lipoprotein lipase deficiency

Amsterdam Molecular Therapeutics, a leader in the field of human gene therapy, announced today results from a long-term efficacy study of Glybera (alipogene tiparvovec) that showed improved chylomicron metabolism could be used as a biomarker for increased lipoprotein lipase (LPL) activity in those patients missing the gene that produces this protein.

20 May 2011

Abbott appreciates FDA Advisory Committee recommendations to retain Trilipix indication for mixed dyslipidemia

The U.S. Food and Drug Administration today held an Endocrinologic and Metabolic Drugs Advisory Committee to review the results of the ACCORD Lipid study as they relate to the use of fenofibric acid (sold as Trilipix in the United States) in combination with a statin in patients with mixed dyslipidemia and at high risk of heart disease.

20 May 2011

Complementary and alternative health practices show promise for management of pain

A variety of complementary and alternative health practices —including meditation and relaxation techniques, manual therapies such as massage and spinal manipulation, meditative exercise forms such as yoga, Tai Chi, and ancient health practices such as acupuncture—show promise for contributing to the management of pain according to research presented at the Annual Scientific Meeting of the American Pain Society, www.ampainsoc.org.

20 May 2011

Bayer, Onyx to present Nexavar-chemotherapy combination Phase 2b trial data in breast cancer at ASCO 2011

Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. today announced results from a Phase 2b trial evaluating Nexavar® (sorafenib) tablets in patients with locally advanced or metastatic breast cancer previously treated with a bevacizumab-containing regimen, which showed that Nexavar was associated with statistically significant improvements in progression-free survival and time-to-progression.

20 May 2011

GIS discovery could help generate stem cells more efficiently for biomedical applications

A team of scientists from Genome Institute of Singapore (GIS) of the Agency for Science, Technology and Research (A*STAR) have shown how proteins involved in controlling genes work together to carry out their functions in stem cells and demonstrated for the very first time, how they can change interaction partners to make other types of cells.

20 May 2011

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Naltrexone reduced inflammation in Crohn's patients in a research study at Penn State College of Medicine.

20 May 2011

Free, online tool to track exercise-induced asthma

Running into breathing problems when you exercise? You may have exercise-induced bronchoconstriction (EIB), commonly referred to as exercise-induced asthma. The American College of Allergy, Asthma and Immunology (ACAAI) has developed a free, easy-to-use online tool to track your symptoms: MyEIBJournal.org.

20 May 2011

VBL to present positive VB-111 preclinical data in metastatic lung cancer at 14th ASGCT

VBL Therapeutics, a clinical-stage biotechnology company committed to the development of novel treatments for immune-inflammatory diseases and cancer, today announced that it will present preclinical data demonstrating VB-111's potential synergy and additive therapeutic effect when administered in combination with the conventional chemotherapy cancer treatments.

20 May 2011

Tornier announces launch of Porous Coated Affiniti Stem for shoulder joint replacement surgery

Tornier Inc. the operating subsidiary of Tornier N.V., a leading global medical device company focused on serving extremities specialists who treat orthopedic conditions of the shoulder, elbow, wrist, hand, ankle and foot, today announced the introduction of the Porous Coated Affiniti Stem for shoulder joint replacement surgery.

20 May 2011

Study: Costs get in way of cancer patients refilling their prescriptions

About 10 percent of cancer patients aren't taking the oral medicines they need either because of the cost or they feel they are already taking too many other drugs, according to a study released by health-care consulting company Avalere Health late Wednesday.

20 May 2011

HealthGrades identifies major flaws in hospital ratings study

The findings of a journal article published in the May issue of the Archives of Surgery are fundamentally flawed and could undermine patients ability to find high quality hospital care, according to HealthGrades. The article, Evaluating Popular Media and Internet-Based Hospital Quality Ratings for Cancer Surgery, compared outcomes for gastrointestinal cancer patients who underwent surgery at hospitals on HealthGrades' "America's 50 Best Hospitals" and US News and World Report's "America's Best Hospitals" lists.

20 May 2011

Lilly's cixutumumab Phase II study results in five subtypes of sarcoma to be presented at 47th ASCO

Eli Lilly and Company announced data from its Phase II study with cixutumumab in five subtypes of sarcoma, a cancer that develops from connective tissues in the body.

20 May 2011

Medical Condition News

Curcumin compound can help head and neck cancer cells overcome resistance to chemotherapy drugs

EMA CHMP issues positive opinion for marketing approval of BENLYSTA

Meta-analysis confirms positive outcomes in patients implanted with Medtronic CoreValve System

Cholesterol drug may help treat mitochondrial diseases

Electrical disturbances in injured brain lead to poor recovery

Surgeon's choices and choice of surgeons influence hospital charges for spinal fusion surgery

Osteoarthritis directly linked to low-fat, high-carb food

RTOG reports on largest trial for newly diagnosed glioblastoma

AMT presents long-term efficacy study of Glybera in treatment of lipoprotein lipase deficiency

Abbott appreciates FDA Advisory Committee recommendations to retain Trilipix indication for mixed dyslipidemia

Complementary and alternative health practices show promise for management of pain

Bayer, Onyx to present Nexavar-chemotherapy combination Phase 2b trial data in breast cancer at ASCO 2011

GIS discovery could help generate stem cells more efficiently for biomedical applications

Naltrexone improves clinical, inflammatory activity in Crohn's disease patients

Free, online tool to track exercise-induced asthma

VBL to present positive VB-111 preclinical data in metastatic lung cancer at 14th ASGCT

Tornier announces launch of Porous Coated Affiniti Stem for shoulder joint replacement surgery

Study: Costs get in way of cancer patients refilling their prescriptions

HealthGrades identifies major flaws in hospital ratings study

Lilly's cixutumumab Phase II study results in five subtypes of sarcoma to be presented at 47th ASCO

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

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