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Genzyme reports positive data from 5-year alemtuzumab Phase 2 study in MS

Genzyme Corp., a subsidiary of sanofi-aventis Group, today reported additional five-year patient data from its completed Phase 2 multiple sclerosis (MS) trial showing that nearly two-thirds of alemtuzumab treated patients remained free of clinically-active disease as much as four years after most patients received their last course of the investigational drug.

15 Apr 2011

Donor-specific antibodies may accelerate arteriosclerosis after kidney transplantation

Kidney transplant recipients who develop antibodies in response to receiving new organs can develop accelerated arteriosclerosis, or narrowing of the arteries that supply blood to the kidney, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results indicate that arteriosclerosis resulting from such donor-specific antibodies may play an important role in organ rejection following transplantation.

15 Apr 2011

Researchers pinpoint new approach that can treat pediatric leukemia

A Loyola University Health System study points to a promising new approach to treating an aggressive and usually fatal leukemia in babies.

15 Apr 2011

GSK announces safety profile of orlistat and alli

GlaxoSmithKline (GSK) is committed to ensuring that consumers and physicians understand the safety profile of orlistat and alli. alli is safe and effective when used as directed. Orlistat is minimally absorbed in the blood and works locally in the gastro-intestinal tract. GSK continues to proactively monitor for the safety of orlistat and share all relevant information with regulatory agencies.

15 Apr 2011

Insight into Cervical Spondylotic Myelopathy

Researchers at the Krembil Neuroscience Centre, Toronto Western Hospital have identified a cell receptor, which is responsible for cell death in the spinal cord in a condition called Cervical Spondylotic Myelopathy.

15 Apr 2011

Stimulation of brain nerves accelerates learning

In a breakthrough that may aid treatment of learning impairments, strokes, tinnitus and chronic pain, UT Dallas researchers have found that brain nerve stimulation accelerates learning in laboratory tests.

15 Apr 2011

Serotonin can help promote human intimacy and romantic feelings

The judgments we make about the intimacy of other couples' relationships appear to be influenced by the brain chemical serotonin, reports a new study published in Biological Psychiatry.

15 Apr 2011

Mortality rates increase 800% when epilepsy and autism occur together

A comprehensive investigation of brain tissue donated to the Autism Speaks Autism Tissue Program (ATP), a postmortem brain tissue donation program, determined that one-third of the brain donors with autism also had epilepsy, and co-morbidity data from the California State Department of Developmental Services revealed a higher than expected rate of mortality in individuals with both autism and epilepsy than for individuals with autism alone.

15 Apr 2011

Researchers report injectable gel can help treat arthritis

Some 25 million people in the United States alone suffer from rheumatoid arthritis or its cousin osteoarthritis, diseases characterized by often debilitating pain in the joints. Now researchers at Brigham and Women's Hospital report an injectable gel that could spell the future for treating these diseases and others.

15 Apr 2011

AHRQ finds 52% increase in medication side effects, injuries between 2004 and 2008

The number of people treated in U.S. hospitals for illnesses and injuries from taking medicines jumped 52 percent between 2004 and 2008 - from 1.2 million to 1.9 million - according to the latest News and Numbers from the Agency for Healthcare Research and Quality.

15 Apr 2011

Researchers classify chronic ulcerative stomatitis as a new autoimmune disease

In the first study investigating the origins of a little-known condition called chronic ulcerative stomatitis, researchers at Tufts University School of Dental Medicine provide evidence that an autoimmune response contributes to the painful oral sores that characterize the disease. The study findings support the classification of CUS as a new autoimmune disease.

15 Apr 2011

LCA announces additional funds for lung cancer research

Today, Lung Cancer Alliance announced that its efforts to secure increased federal research funding for lung cancer achieved another victory as an additional $12.8 million was included in the Department of Defense Congressionally Directed Medical Research Program which was part of the FY2011 budget compromise approved by Congress.

15 Apr 2011

Takeda announces EDARBI availability in U.S. pharmacies for hypertension treatment

Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, Takeda Pharmaceuticals North America, Inc., today announced that EDARBI, an angiotensin II receptor blocker approved for the treatment of hypertension, or high blood pressure, is now available by prescription for adults in U.S. pharmacies.

15 Apr 2011

Walking slows progression of nonalcoholic fatty liver disease in obese people

Walking on a treadmill for one hour a day may slow the progression of nonalcoholic fatty liver disease in obese people with prediabetes by jump-starting their metabolism and slowing the oxidative damage wrought by the condition, say researchers at the Cleveland Clinic.

15 Apr 2011

Researchers show how TET1 enzyme controls fetal development and fights cancer

To ensure normal fetal development and prevent disease, it is crucial that certain genes are on or off in the right time intervals. Researchers in Professor Kristian Helin's group at BRIC, University of Copenhagen, have now shown how the TET1 enzyme controls the activity of our genes. The results are just published in the journal Nature.

15 Apr 2011

AAN, PDF honor Boston researcher with Clinician Scientist Development Award

A clinician scientist at Massachusetts General Hospital in Boston is receiving $240,000 to further his research into how stem cells may be used to treat Parkinson's disease through the American Academy of Neurology Foundation and the Parkinson's Disease Foundation Clinician Scientist Development Award in Parkinson's Disease Research.

15 Apr 2011

Study identifies why salt-sensitive hypertension develops

New research from Case Western Reserve University School of Medicine and Kent State University shows that salt intake raises blood pressure because it makes it harder for the cardiovascular system to simultaneously juggle the regulation of blood pressure and body temperature.

15 Apr 2011

New MRI device can make deep brain stimulation effective for patients

A new MRI device that guides surgeons as they implant electrodes into the brains of people with Parkinson's disease and other neurological disorders could change the way this surgery, called deep brain stimulation, is performed at medical centers across the country, according to a group of doctors at University of California, San Francisco.

15 Apr 2011

NIST's new reference can aid in Huntington's disease diagnosis

A new Standard Reference Material from the National Institute of Standards and Technology will help clinical genetics labs accurately diagnose Huntington's disease, an inherited degenerative brain disorder that usually begins between ages 35 and 50 and progressively leads to physical impairment, dementia and death.

15 Apr 2011

Scientists link increase of calcium influx in brain neurons to long-term memory

Using advanced imaging technology, scientists from the Florida campus of The Scripps Research Institute have identified a change in chemical influx into a specific set of neurons in the common fruit fly that is fundamental to long-term memory.

15 Apr 2011