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Polaris' ADI-PEG 20 exhibits potential against AML, GBM and bladder cancer

Polaris Group announced today that data from preclinical studies suggest ADI-PEG 20, the Company's pegylated arginine deiminase therapeutic, may be effective in treating acute myeloid leukemia (AML), glioblastoma multiforme (GBM) and bladder cancer.

8 Apr 2011

FDA grants tentative approval for Hi-Tech Pharmacal's generic Combigan ANDA

Hi-Tech Pharmacal Co., Inc., a specialty pharmaceuticals company, announced today that the US Food and Drug Administration, (FDA) granted tentative approval for the Company's Abbreviated New Drug Application, (ANDA) for brimonidine tartrate with timolol maleate ophthalmic solution, the generic for Allergan's Combigan® ophthalmic solution which had sales of $108 million for the 12 months ended December 2010 according to IMS sales data.

8 Apr 2011

Watson confirms patent challenge by Alcon for generic Vigamox

Watson Pharmaceuticals, Inc. today confirmed that its subsidiary, Watson Laboratories, Inc., filed an Abbreviated New Drug Application (ANDA) with the U.S. Food and Drug Administration (FDA) seeking approval to market Moxifloxacin Hydrochloride Ophthalmic Solution USP, 0.5%. Watson's Moxifloxacin Hydrochloride Ophthalmic Solution USP, 0.5% is a generic version of Alcon, Inc.'s Vigamox®, an antibiotic solution that is indicated for the treatment of bacterial conjunctivitis.

8 Apr 2011

FDA accepts Antares Pharma's Anturol NDA for filing, assigns PDUFA date

Antares Pharma, Inc. today announced the New Drug Application (NDA) for Anturol® Gel in patients with overactive bladder (OAB) was accepted for filing for review by the U.S. Food and Drug Administration (FDA). Anturol is an oxybutynin gel incorporating Antares' ATD Gel technology.

8 Apr 2011

Vascular Disease Foundation invites applicants for ambassador program

If you or someone you love have been affected by vascular disease and have a willingness to help others, the Vascular Disease Foundation (VDF) is calling for applications to join its ambassador program to help promote vascular disease awareness.

8 Apr 2011

Researchers identify new gene that predisposes people to both autism, epilepsy

Researchers from the CHUM Research Centre have identified a new gene that predisposes people to both autism and epilepsy.

8 Apr 2011

New report finds 13,000 cancer cases per year in the UK due to alcohol consumption

Alcohol causes at least 13,000 cases of cancer a year in the UK, according to a new report published in the British Medical Journal today.

8 Apr 2011

Adult survivors of childhood CNS tumors have persistent, unmet health care needs

Patients treated in childhood for tumours of the central nervous system have persistent and unmet health care needs even in adulthood, according to a comprehensive study from Karolinska Institutet which investigated an entire cohort of patients in Sweden.

8 Apr 2011

Biochemical battle of the bulge: New developments

Dozens of researchers in the coming days will lay out what's around the corner in the biochemical battle of the bulge as part of the Experimental Biology 2011 conference in Washington, D.C.

8 Apr 2011

Computational modeling provides more knowledge of lipoprotein properties

Computational modeling increases our knowledge of lipoprotein properties that cannot be measured using experimental methods. Lipoproteins are particles that transport cholesterol in our bloodstream. According to the doctoral dissertation of Master of Science in Technology Linda Kumpula (Aalto University School of Science), the differences in the composition, size and number of lipoprotein particles transporting cholesterol in individuals can be computationally modeled using experimental data.

8 Apr 2011

New publication on therapeutic hypothermia and temperature management

The successful use and evaluation of therapeutic hypothermia to improve survival and reduce the risk of neurological consequences following an out-of-hospital heart attack are explored in the premier issue of Therapeutic Hypothermia and Temperature Management, a new quarterly peer-reviewed journal published by Mary Ann Liebert, Inc.

8 Apr 2011

Study: Majority of hospital deaths are due to late cancer diagnosis

Late cancer diagnosis in Northern Ireland contributes to hospital deaths despite patient's preference to die at home according to a major report launched at Queen's University Belfast.

8 Apr 2011

Loyola's HARRT program enhances emergency angioplasty times

The availability of an in-house, around-the-clock interventional cardiology team dramatically decreases the time it takes to restore blood flow to heart attack patients, according to data presented this week.

8 Apr 2011

Orthopaedic surgeon: Broken bones and itching more common during spring weather

Spring weather signals the start of many outdoor activities as people of all ages eagerly embrace the change in weather. Paul Prinz, MD, orthopaedic surgeon at Gottlieb Memorial Hospital, part of Loyola University Health System says, "Broken bones and fractures occur year 'round but the change in seasons always creates an increase of patients in our offices."

8 Apr 2011

Researchers determine age of atherosclerotic plaques using carbon dating

In a new study performed in humans, researchers from Sweden's Karolinska Institutet have determined the age of atherosclerotic plaques by taking advantage of Carbon-14 residues in the atmosphere, prevailing after the extensive atomic bomb tests in the 50ties and 60ties.

8 Apr 2011

Caffeine disrupts glucose metabolism and may contribute to type 2 diabetes

A growing body of research suggests that caffeine disrupts glucose metabolism and may contribute to the development and poor control of type 2 diabetes, a major public health problem.

8 Apr 2011

Kidney transplantion more effective than previously thought

A new study from Mayo Clinic, the largest long-term study of kidney transplant recipients published to date, demonstrates that progressive damage to kidney transplants may be less common and less severe than previously reported.

8 Apr 2011

First trial to test shared decision making for weight-loss surgery

A video-based decision aid helped severely obese people to make more informed choices about bariatric surgery and reach more certainty about them, according to a trial involving 152 Group Health patients, e-published in Obesity in advance of print. This randomized controlled trial is the first to test shared decision making for weight-loss surgery.

8 Apr 2011

New Clinical Practice Guideline for evaluation and treatment of pituitary incidentalomas

Today, The Endocrine Society released a new Clinical Practice Guideline (CPG) for the evaluation and treatment of pituitary incidentalomas. The CPG is published in the April 2011 issue of the Journal of Clinical Endocrinology & Metabolism (JCEM), a publication of The Endocrine Society.

8 Apr 2011

GlaxoSmithKline, XenoPort receive FDA approval for Horizant to treat RLS

On April 6, the U.S. Food and Drug Administration approved Horizant Extended Release Tablets, a once-daily treatment for moderate-to-severe restless legs syndrome.

8 Apr 2011