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AstraZeneca receives FDA approval for vandetanib to treat medullary thyroid cancer

The U.S. Food and Drug Administration today approved vandetanib to treat adult patients with late-stage (metastatic) medullary thyroid cancer who are ineligible for surgery and who have disease that is growing or causing symptoms.

7 Apr 2011

Avila announces successful completion of AVL-292 Phase 1a clinical studies for B-cell cancers

Avila Therapeutics, Inc., a biotechnology company developing novel targeted covalent drugs, today announced that it has successfully completed two Phase 1a clinical studies for AVL-292, its orally-available, selective inhibitor of Bruton's tyrosine kinase (Btk).

6 Apr 2011

Strawberries may slow progression of precancerous lesions in the esophagus

Freeze-dried strawberries may be an alternative to drugs for the prevention of esophageal cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.

6 Apr 2011

Asuragen launches InformThyroid, a panel of molecular markers

Asuragen, Inc. announced today the launch of Inform™Thyroid, a panel of molecular markers used on Fine Needle Aspirates (FNA) of thyroid nodules to aid physicians in the management of thyroid cancer.

6 Apr 2011

ImClone Systems initiates IMC-3C5 Phase 1 trial in patients with advanced solid tumours

Circadian Technologies announced today that its licensee ImClone Systems, a wholly-owned subsidiary of Eli Lilly and Company, has advised that it has commenced the first Phase 1 clinical trial of its fully-human monoclonal antibody IMC-3C5.

6 Apr 2011

Americans concerned about thyroid cancer development from mammography

Some Americans have expressed concern, due to an erroneous media report, that the small amount of radiation a patient receives from a mammogram may significantly increase the likelihood of developing thyroid cancer. This concern simply is not supported in scientific literature.

6 Apr 2011

BioWa, OBT enter license agreement to advance ADCC programs

BioWa, Inc. and Oxford BioTherapeutics Ltd today announced that they have entered into a license agreement to provide OBT with access to BioWa's patented POTELLIGENT Technology platform for the development of antibody-dependent cellular cytotoxicity enhanced antibodies.

6 Apr 2011

Only half of post-combat military service members having mental health issues seek treatment

Approximately 50 percent of military servicemembers returning from combat duty report experiencing a mental health issue, but only half of them have sought treatment. That is according to a recently released study titled Joining Forces America, a comprehensive survey of more than 1,000 military servicemembers, family members of servicemembers, and mental health professionals.

6 Apr 2011

Results of study evaluating potential inhibitory effects of PPIs on Plavix presented at ACC 2011

Takeda Pharmaceuticals North America, Inc. announced the presentation of new study results, which evaluated the potential inhibitory effects of certain proton pump inhibitors (PPIs) on Plavix (clopidogrel bisulfate). The results showed that in healthy subjects, clopidogrel's active metabolite and inhibition of platelet function were reduced less by the co-administration of clopidogrel with dexlansoprazole or lansoprazole, rather than esomeprazole.

6 Apr 2011

ICD therapy can improve ischemic cardiomyopathy survival rates

Most patients with ischemic cardiomyopathy and dilated cardiomyopathy who have an implantable cardioverter-defibrillator now live more than seven years and those ICD patients with hereditary heart disease can live for decades, based on a scientific paper that will be presented at the American College of Cardiology Scientific Sessions in New Orleans, April 1-3.

6 Apr 2011

Roswell Park Cancer Institute selected to be part of Cancer Immunotherapy Trials Network

Roswell Park Cancer Institute (RPCI) is one of 27 North American research institutions that have been selected to be part of the Cancer Immunotherapy Trials Network (CITN), a new immunotherapy initiative funded by the National Cancer Institute (NCI). Kunle Odunsi, MD, PhD, FRCOG, FACOG, Director of the Center for Immunotherapy and Chair of Gynecologic Oncology at RPCI, will serve as Principal Investigator of the Institute's role in this collaborative investigative effort.

6 Apr 2011

Researchers develop new stroke rehabilitation devices

Devices which could be used to rehabilitate the arms and hands of people who have experienced a stroke have been developed by researchers at the University of Southampton.

6 Apr 2011

Pancreatic Cancer Action Network, AACR honor NYU School of Medicine's scientist with Fellowship

NYU School of Medicine's Cosimo Commisso, PhD, a postdoctoral fellow in the Department of Biochemistry, is the 2011 recipient of The Pancreatic Cancer Action Network-American Association for Cancer Research Fellowship, a one-year grant designed to support pancreatic cancer research.

6 Apr 2011

SWHR roundtable to examine sex differences in Alzheimer's disease

At the Women's Health 2011: 19th Annual Conference plenary session, A Wake Up Call to Clinicians: Alzheimer's and Early Diagnosis, Geoffrey Beene Foundation President, Meryl Comer announced the Society for Women's Health Research's upcoming one-day Alzheimer's roundtable, exploring sex differences in this increasingly prevalent disease.

6 Apr 2011

Record number of medicines for various cancers in clinical trials

A record 887 medicines for various of cancers are in clinical trials or awaiting Food and Drug Administration (FDA) review—well over double the number in the pipeline just six years ago, according to a report unveiled today by the Pharmaceutical Research and Manufacturers of America (PhRMA).

6 Apr 2011

Celldex presents CDX-1127 preclinical data against cancer at AACR meeting

Celldex Therapeutics, Inc. today announced that new data on its preclinical therapeutic antibody program, CDX-1127, is being presented in a poster presentation at the 2011 American Association for Cancer Research 102nd Annual Meeting in Orlando, FL.

6 Apr 2011

Specific lipids in tumours linked to cancer progression and patient survival

Activation of lipid metabolism is an early event in carcinogenesis and a central hallmark of many cancers. However, the precise molecular composition of lipids in tumours remains generally poorly characterised. Scientists from VTT Technical Research Centre of Finland and the Charité Hospital have found lipids in tumours which are associated with cancer progression.

6 Apr 2011

Work, social and family disability affect 50% of patients with bipolar disorder

Such was the conclusion obtained in a study conducted at the University of Granada that was recently awarded a prize in the IV Spain-Portugal Meeting on Therapeutical Adherence held in Oporto.

6 Apr 2011

Aeterna Zentaris presents AEZS-131 data against cancer at AACR meeting

Aeterna Zentaris Inc. today announced that a poster on its highly selective Erk 1/2 inhibitor anticancer compound, AEZS-131, was presented at the 102nd annual meeting of the American Association for Cancer Research currently held at the Orange County Convention Center in Orlando, Florida.

6 Apr 2011

Heart patients share perspectives on deactivation, donation and reuse of ICD devices

Each year, more than 100,000 patients in the U.S. undergo implantation of a new implantable cardioverter defibrillator (ICD) for heart rhythm abnormalities. This number constitutes a 20-fold increase over the last 15 years. Current medical guidelines advocate discussion of end of life care of these medical devices, including deactivation, but many patients may not understand their options.

6 Apr 2011

Medical Condition News

AstraZeneca receives FDA approval for vandetanib to treat medullary thyroid cancer

Avila announces successful completion of AVL-292 Phase 1a clinical studies for B-cell cancers

Strawberries may slow progression of precancerous lesions in the esophagus

Asuragen launches InformThyroid, a panel of molecular markers

ImClone Systems initiates IMC-3C5 Phase 1 trial in patients with advanced solid tumours

Americans concerned about thyroid cancer development from mammography

BioWa, OBT enter license agreement to advance ADCC programs

Only half of post-combat military service members having mental health issues seek treatment

Results of study evaluating potential inhibitory effects of PPIs on Plavix presented at ACC 2011

ICD therapy can improve ischemic cardiomyopathy survival rates

Roswell Park Cancer Institute selected to be part of Cancer Immunotherapy Trials Network

Researchers develop new stroke rehabilitation devices

Pancreatic Cancer Action Network, AACR honor NYU School of Medicine's scientist with Fellowship

SWHR roundtable to examine sex differences in Alzheimer's disease

Record number of medicines for various cancers in clinical trials

Celldex presents CDX-1127 preclinical data against cancer at AACR meeting

Specific lipids in tumours linked to cancer progression and patient survival

Work, social and family disability affect 50% of patients with bipolar disorder

Aeterna Zentaris presents AEZS-131 data against cancer at AACR meeting

Heart patients share perspectives on deactivation, donation and reuse of ICD devices

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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