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Plexxikon selects Clinipace to manage 4 clinical trials for RA treatment

Clinipace Worldwide, a global digital clinical research organization, announced today that Plexxikon Inc., a leader in the structure-guided discovery and development of novel small molecule pharmaceuticals to treat human disease, has selected Clinipace to manage all aspects of four clinical trials comprising a Phase 1 healthy volunteer study, a Phase 1b rheumatoid arthritis study, and two phase 2 oncology studies.

16 Mar 2011

New self-monitoring blood glucose sensor uses tear fluid as sample

People with diabetes could be helped by a new type of self-monitoring blood glucose sensor being developed by Arizona State University engineers and clinicians at Mayo Clinic in Arizona.

16 Mar 2011

Insight into Lyme disease

Researchers recently developed novel diagnostic tools able to distinguish between the various strains of bacteria responsible for causing Lyme disease. For more than a decade, only one strain of B. burgdorferi had been sequenced, and although that helped research efforts, it was not sufficient to understand the relationship between geographic variations in strains and disease characteristics.

16 Mar 2011

Anti-cancer drug loaded microcarriers successfully guided to targeted area in the liver

Soon, drug delivery that precisely targets cancerous cells without exposing the healthy surrounding tissue to the medication's toxic effects will no longer be an oncologist's dream but a medical reality, thanks to the work of Professor Sylvain Martel, Director of the Nanorobotics Laboratory at Polytechnique Montr-al.

16 Mar 2011

Manchester research offers hope for congenital hyperinsulinism treatment

University of Manchester scientists have led an international team to discover new treatments for a rare and potentially lethal childhood disease that is the clinical opposite of diabetes mellitus.

16 Mar 2011

Classifying gambling subtypes does not predict treatment outcomes

Approximately two million adults in the United States meet criteria for pathological gambling, and another four to six million are considered problem gamblers, according to the National Council on Problem Gambling. A study by researchers at Wayne State University reveals that gambling addiction treatment is not one-size-fits-all, but it is difficult to predict which style of treatment is best for the various forms of gambling addiction.

16 Mar 2011

Researchers identify genetic cause of magnesium deficiency

Researchers and scientists of the Charité - Universitätsmedizin Berlin, in cooperation with the Max Delbrück Center for Molecular Medicine, and colleagues from the Netherlands, Belgium, Switzerland and the Czech Republic have succeeded in identifying a genetic cause of magnesium deficiency.

16 Mar 2011

BRAF gene defect leads to pilocytic astrocytoma in children

Pilocytic astrocytoma, the most common brain tumor in children, is usually slow-growing and benign. However, surgeons often cannot completely remove the diffusely growing tumor.

16 Mar 2011

Mile Square earns excellence in heart care

Mile Square Health Center at 2045 W. Washington Blvd. was named an Illinois "Your Healthcare Plus" top performer for excellence in caring for patients with heart failure.

16 Mar 2011

Researchers discover molecular switch for insulin secretion

Johns Hopkins researchers believe they have uncovered the molecular switch for the secretion of insulin — the hormone that regulates blood sugar — providing for the first time an explanation of this process.

16 Mar 2011

Psychological disorders may be more prevalent in adolescent acne patients

America's prom season is on the horizon and with it comes distress for thousands of teens who will be distraught to see a pimple raise its ugly head on their nose or chin.

16 Mar 2011

March of Dimes to honor fragile X syndrome researcher with Lifetime Achievement award

A world-renowned fragile X syndrome researcher, who was the first to identify the long-sought genetic abnormality responsible for this disorder, will be honored by the March of Dimes.

16 Mar 2011

AstraZeneca commences NKTR-118 Phase III clinical programme for opioid-induced constipation

AstraZeneca today announced enrolment of the first patient in the Phase III clinical programme for NKTR-118, an oral peripherally-acting opioid antagonist being investigated for the treatment of opioid-induced constipation (OIC).

16 Mar 2011

Post-stroke depression management can lead to better physical functioning

Stroke patients who are not successfully treated for depression are at higher risk of losing some of their capability to function normally, according to a study in the March 15, 2011 issue of the journal Neurology.

16 Mar 2011

Nuclear fallout-related health fears rise in Japan

Concerns regarding health risks "rose dramatically in Japan Tuesday" after officials said more radiation was released at a nuclear power plant that was damaged in the tsunami, the Associated Press reports. In an address to the nation, Prime Minister Naoto Kan said radiation had been emitted from four reactors. "The level seems very high, and there is still a very high risk of more radiation coming out," he said.

16 Mar 2011

Hydro-stomach CT imaging is not a reliable tool for EGC detection: Study

Traditionally, both air and tap water have been used as oral contrast agents to achieve adequate gastric distension for preoperative computed tomography imaging in patients with early gastric cancer.

16 Mar 2011

Study investigates physiological changes within brain due to Prozac treatment

Selective serotonin reuptake inhibitors (SSRI) such as Prozac are regularly used to treat severe anxiety and depression. They work by immediately increasing the amount of serotonin in the brain and by causing long term changes in brain function. However it can take weeks of treatment before a patient feels any effect and both beneficial effects and side effects can persist after treatment is stopped.

16 Mar 2011

Self-sample HPV test can help increase cervical screening uptake among women

Home tests for the human papillomavirus could help increase the take-up of cervical screening among women who do not respond to screening invitations, new research shows today.

16 Mar 2011

Millennium, SGEN expand ADC collaboration

Seattle Genetics, Inc. announced today that Millennium: The Takeda Oncology Company, a wholly owned subsidiary of Takeda Pharmaceutical Company Limited, has paid an undisclosed fee to exercise an option to designate a second antigen target under the parties' existing antibody-drug conjugate (ADC) collaboration.

16 Mar 2011

Unigene initiates oral PTH Phase 2 study in postmenopausal women with osteoporosis

Unigene Laboratories, Inc. a leader in the design, delivery, manufacture and development of peptide-based therapeutics announced today the dosing of the first subject in a Phase 2 study with an experimental oral parathyroid hormone analog for the treatment of osteoporosis in postmenopausal women.

16 Mar 2011