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Teva, Active Biotech report positive initial results from laquinimod Phase III study in multiple sclerosis

Teva Pharmaceutical Industries Ltd. and Active Biotech announced today initial results from the two-year Phase III ALLEGRO study, which demonstrated that relapsing-remitting multiple sclerosis (MS) patients treated with 0.6 mg daily oral laquinimod experienced a statistically significant reduction in annualized relapse rate compared to placebo. Additional clinical endpoints, including significant reduction in disability progression, as measured by Expanded Disability Severity Scale (EDSS), were also achieved.

9 Dec 2010

Research findings could lead to new therapies to correct neurological disorders

Yale University researchers have found that a single molecule not only connects brain cells but also changes how we learn. The findings, reported in the December 9 issue of the journal Neuron, may help researchers discover ways to improve memory and could lead to new therapies to correct neurological disorders.

9 Dec 2010

Nottingham researchers develop new 'score' to detect heart disease in younger people

Experts at The University of Nottingham have developed a new 'score' to help GPs detect heart disease in younger people - before it damages their health.

9 Dec 2010

Researchers find weak association between parent-child dietary intake

As primary caregivers, parents are often believed to have a strong influence on children's eating behaviors. However, previous findings on parent-child resemblance in dietary intakes are mixed. Researchers from the Johns Hopkins Bloomberg School of Public Health reviewed and assessed the degree of association and similarity between children's and their parents' dietary intake based on worldwide studies published since 1980. The meta-analysis is featured in the December issue of the Journal of Epidemiology and Community Health.

9 Dec 2010

p53 activation offers a novel strategy for cancer therapy

A pioneering clinical trial is testing the effectiveness in leukemia of a small molecule that shuts down MDM2, a protein that can disable the well-known tumor suppressor p53.

9 Dec 2010

Exergen's TemporalScanner demonstrates accuracy in temperature assessment for surgical patients

Temperatures taken orally or by temporal artery thermometry "are an accurate means of temperature assessment for adult patients undergoing colorectal or gynecology surgery," according to analysis published by the Journal of PeriAnesthesia Nursing. Accurate temperature readings are necessary to determine when to intervene for patients at all stages of their hospitalizations but especially during and immediately after surgical procedures to avoid post-operative complications.

9 Dec 2010

New objective criteria for evaluating hemostatic efficacy in treatment of VWD

Octapharma USA researchers presented new stringent, objective criteria used in the evaluation of hemostatic efficacy in the treatment of von Willebrand disease and reported on their application of these criteria in clinical trials during the recently completed National Hemophilia Foundation Annual Meeting.

9 Dec 2010

Bioheart group to advance BRIDGE TO RECOVERY clinical trial

Bioheart, Inc. announced today that at the American Heart Association Annual Meeting, it finalized the formation of a working group. The group's focus is to advance a BRIDGE TO RECOVERY clinical trial, combining a left ventricle assist device (LVAD) and Bioheart's MyoCell adult muscle stem cell composition and Bioheart's MyoCath needle tipped catheter delivery system.

9 Dec 2010

Poorly educated people more likely to be admitted in hospital with chronic heart failure

Results from a large European study suggest that poorly educated people are more likely to be admitted to hospital with chronic heart failure than the better educated, even after differences in lifestyle have been taken into account. The study is published online today (Thursday 9 December) in the European Heart Journal.

9 Dec 2010

New types of dietary fiber now under development

High-fiber foods are on the way to becoming tastier and more appealing to consumers thanks to new types of dietary fiber now under development. These consumer friendlier forms of fiber, which could be a boon to health, are the topic of an article in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine.

9 Dec 2010

New technique jumpstarts growth of nerve fibers to reverse stroke damage

A new technique that jumpstarts the growth of nerve fibers could reverse much of the damage caused by strokes, researchers report in the Jan. 7, 2011 issue of the journal Stroke.

9 Dec 2010

Euthymics announces EB-1010 Phase II data for major depressive disorder at ACNP meeting

9 Dec 2010

Expert panel explores how to engage pediatricians, primary care physicians in preventing childhood obesity

As the prevalence of childhood obesity approaches epidemic levels, physicians on the "front line" need to become more involved in obesity prevention and weight management to reverse this dangerous trend among their young patients. But several obstacles discourage pediatricians and other primary care physicians from taking a more active role in managing childhood obesity.

9 Dec 2010

Clinical data of pomalidomide for treating patients with multiple myeloma presented at ASH 2010

Celgene International Sàrl today announced that its next IMiD compound, pomalidomide, was evaluated in three separate investigational trials of patients with multiple myeloma who were relapsed or refractory after prior treatments including lenalidomide, thalidomide and bortezomib. The clinical data were presented at the 52nd Annual Meeting of the American Society of Hematology in Orlando, Florida.

9 Dec 2010

DPT granted FDA approval to manufacture Collagenase SANTYL Ointment for wound care

DPT Laboratories, Ltd., a pharmaceutical contract development and manufacturing organization, announced today that it received FDA approval to manufacture commercial supplies of a leading sterile ointment for wound care at its Center of Excellence for Sterile & Specialty Products in Lakewood, N.J. Beginning this month, Healthpoint will ship commercial lots of Collagenase SANTYL® Ointment produced at DPT's Lakewood facility to its North American customers.

9 Dec 2010

ADHD, developmental RD have common genetic influences: Study

Attention Deficit Hyperactivity Disorder and developmental reading disability are complex childhood disorders that frequently occur together; if a child is experiencing trouble with reading, symptoms of ADHD are often also present.

9 Dec 2010

Euthymics's EB-1010 effective in treatment of major depressive disorder: Study

Euthymics Bioscience, Inc. today will present Phase II clinical data demonstrating that its lead product candidate EB-1010, a next-generation antidepressant, is effective for treating major depressive disorder (MDD) based on multiple standard measures of outcome for depression. EB-1010 also improved measures of anhedonia, a hallmark symptom of MDD, which is characterized by the inability to experience pleasure.

9 Dec 2010

Alkermes announces preliminary results from ALKS 33 Phase 2 study in alcohol dependence

Alkermes, Inc. today announced preliminary results from a phase 2 clinical study of ALKS 33, one of Alkermes' proprietary candidates for the treatment of reward disorders and other central nervous system (CNS) disorders. The 12-week study was designed to assess the safety and efficacy of daily oral administration of three different dose levels of ALKS 33 compared to placebo in 400 alcohol dependent patients.

9 Dec 2010

Estrogen receptor beta inactivates critical genes, arrests cancer cell growth

Bionovo, today announced the publication of a study demonstrating that ERb causes cancer cell growth arrest by inactivating critical genes and enzymes responsible for cell growth. These results provide evidence that drugs that stimulate the production of or activate ERb are potential new therapies to prevent breast cancer.

9 Dec 2010

Genetics in Medicine: Women who carry high-risk BRCA mutations opt for surgery

In women who test positive for BRCA 1/2 mutations associated with a high risk of breast or ovarian cancer, some key psychological factors influence the decision to undergo risk-reducing surgery, reports the December Genetics in Medicine, the official peer-reviewed journal of The American College of Medical Genetics.

8 Dec 2010

Medical Condition News

Teva, Active Biotech report positive initial results from laquinimod Phase III study in multiple sclerosis

Research findings could lead to new therapies to correct neurological disorders

Nottingham researchers develop new 'score' to detect heart disease in younger people

Researchers find weak association between parent-child dietary intake

p53 activation offers a novel strategy for cancer therapy

Exergen's TemporalScanner demonstrates accuracy in temperature assessment for surgical patients

New objective criteria for evaluating hemostatic efficacy in treatment of VWD

Bioheart group to advance BRIDGE TO RECOVERY clinical trial

Poorly educated people more likely to be admitted in hospital with chronic heart failure

New types of dietary fiber now under development

New technique jumpstarts growth of nerve fibers to reverse stroke damage

Euthymics announces EB-1010 Phase II data for major depressive disorder at ACNP meeting

Expert panel explores how to engage pediatricians, primary care physicians in preventing childhood obesity

Clinical data of pomalidomide for treating patients with multiple myeloma presented at ASH 2010

DPT granted FDA approval to manufacture Collagenase SANTYL Ointment for wound care

ADHD, developmental RD have common genetic influences: Study

Euthymics's EB-1010 effective in treatment of major depressive disorder: Study

Alkermes announces preliminary results from ALKS 33 Phase 2 study in alcohol dependence

Estrogen receptor beta inactivates critical genes, arrests cancer cell growth

Genetics in Medicine: Women who carry high-risk BRCA mutations opt for surgery

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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