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Proteins could lead to new therapeutic target for NF2: Wistar Institute researchers

The proteins that provide cells with a sense of personal space could lead to a therapeutic target for Neurofibromatosis Type 2, an inherited cancer disorder, according to researchers at The Wistar Institute. Their findings, which appear in the April 12 issue of the journal Cancer Cell, could have profound implications for NF2 and related cancers, such as mesothelioma.

16 Apr 2011

Children who have eczema with hay fever more likely to develop allergic asthma

Children who have eczema, particularly when occurring with hay fever, are nine times more likely to develop allergic asthma in their 40s, a new study reveals.

16 Apr 2011

Opexa's Tovaxin Phase IIb study data in MS presented at AAN meeting

Opexa Therapeutics, Inc., a company developing Tovaxin, a novel T-cell therapy for multiple sclerosis, today presented important efficacy data at the American Academy of Neurology 63rd Annual Meeting.

16 Apr 2011

Boehringer Ingelheim's dabigatran etexilate receives positive opinion from EMA committee

Boehringer Ingelheim's novel oral anticoagulant dabigatran etexilate, received a positive opinion from the European Medicines Agency's medicinal committee today.

16 Apr 2011

Top-line results from Pfizer's tofacitinib Phase 3 study in rheumatoid arthritis

Pfizer Inc. announced today top-line results from the ORAL Scan Phase 3 study of tofacitinib, formerly known as tasocitinib, an investigational, novel, oral JAK inhibitor.

15 Apr 2011

Novocure receives FDA approval for NovoTTF-100A System to treat GBM

The U.S. Food and Drug Administration recently approved the NovoTTF-100A System, a new device to treat adults with glioblastoma multiforme that recurs or progresses after receiving chemotherapy and radiation therapy.

15 Apr 2011

Patients with heart failure can benefit from left ventricular assist device

Non-cardiac surgery can be performed safely in patients with a heart device typically implanted into patients waiting for a transplant, according to a study at Henry Ford Hospital in Detroit.

15 Apr 2011

New approach links cancer cell metabolism with poor clinical outcome

Identifying gene mutations in cancer patients to predict clinical outcome has been the cornerstone of cancer research for nearly three decades, but now researchers at the Kimmel Cancer Center at Jefferson have invented a new approach that instead links cancer cell metabolism with poor clinical outcome. This approach can now be applied to virtually any type of human cancer cell.

15 Apr 2011

JNJ, Merck sign distribution agreement for REMICADE and SIMPONI

Merck (NYSE: MRK), known as MSD outside the United States and Canada, and Johnson & Johnson (NYSE: JNJ) and its subsidiary Centocor Ortho Biotech Inc., today announced that the companies have reached agreement to amend the distribution rights to REMICADE and SIMPONI, which treat chronic inflammatory diseases such as rheumatoid arthritis.

15 Apr 2011

Study: Low-carb diet greatly reduces liver fat

Curbing carbohydrates is more effective than cutting calories for individuals who want to quickly reduce the amount of fat in their liver, report UT Southwestern Medical Center researchers.

15 Apr 2011

Saint Louis professor develops new high-flow brain bypass procedure

On the cover of a recent edition of the journal Neurosurgery, the highest circulation medical journal in the field, readers saw an artist's intricate depiction of the high-flow brain bypass technique developed by Saint Louis University professor of neurosurgery, Saleem Abdulrauf, M.D.

15 Apr 2011

Patients with COPD can benefit from ICS use

Patients with chronic obstructive pulmonary disease who are hospitalized for pneumonia and treated with inhaled corticosteroids have decreased mortality when compared to those who are not treated with ICS, according to a retrospective analysis of almost 16,000 COPD patients admitted to VA hospitals.

15 Apr 2011

Genentech receives FDA approval for Actemra to treat juvenile idiopathic arthritis

The U.S. Food and Drug Administration today approved Actemra, given alone or in combination with methotrexate, for the treatment of active systemic juvenile idiopathic arthritis in children ages 2 years and older.

15 Apr 2011

Patients with RLS more likely to develop cardiovascular conditions

Results from a two-year retrospective cohort study presented at the 63rd Annual Meeting of the American Academy of Neurology, Hawaii, U.S., showed that patients were significantly more likely to develop cardiovascular conditions, including hypertension, cardiac dysrhythmias and chronic ischemic heart diseases after an initial diagnosis of RLS, as compared to controls without RLS.

15 Apr 2011

Study: CCSVI may result from multiple sclerosis progression

A just released study on the relationship between multiple sclerosis and chronic cerebral venous insufficiency, a narrowing of the extracranial veins that restricts the normal outflow of blood from the brain, found that CCSVI may be a result of MS, not a cause.

15 Apr 2011

New insights into dynamics of amyloid fibrils

A research study, published yesterday in the Journal of the American Chemical Society, demonstrates that the aggregation of amyloid-beta proteins into amyloid fibrils characteristic of Alzheimer's disease is not irreversible, as previously thought.

15 Apr 2011

ANNA releases new textbook on nephrology nurse's role

With the rate of chronic kidney disease in America spiking over the past two decades, the role of the nephrology nurse has become increasingly important as more lives are affected.

15 Apr 2011

Merz launches 'Make Your Mark' campaign to raise awareness on cervical dystonia

Merz Pharmaceuticals, LLC, maker of XEOMIN, a botulinum toxin type A free from accessory proteins, today announced the launch of the "Make Your Mark" campaign.

15 Apr 2011

Chicago doctor develops new non-surgical procedure to alleviate back pain

Dr. Jeff Winternheimer of the Illinois Back Institute has developed a revolutionary non-surgical procedure to alleviate back pain. Both professional athletes and everyday back and neck pain sufferers have been flocking to his four Chicago area clinics to see for themselves.

15 Apr 2011

Adhering to cancer prevention guidelines reduces risk of cancer, cardiovascular disease

A study of more than 100,000 men and women over 14 years finds nonsmokers who followed recommendations for cancer prevention had a lower risk of death from cancer, cardiovascular disease, and all-causes. The study appears early online in Cancer Biomarkers, Epidemiology, and Prevention, and was led by American Cancer Society epidemiologists.

15 Apr 2011