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Gelatinase B expression enhanced in gastric cancer compared to normal gastric mucosa

Gastric cancer in Mexico is the most frequent gastrointestinal malignant neoplasm. Several precursor conditions, such as chronic gastritis, have been associated with the development of gastric cancer. The gelatinases MMP-2 and MMP-9, members of the metalloproteinase family, are fundamental enzymes in extracellular matrix remodelling. The extracellular matrix is composed of secreted molecules outside cells which provides structural support and regulates cell behaviour.

9 Apr 2010

Mayo Clinic researchers to present XOMA 052 data at 101st AACR Annual Meeting

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced that researchers from the Mayo Clinic will be presenting data on the use of XOMA's high-affinity antibody to interleukin-1 beta (IL-1 beta), XOMA 052, in myeloma at the 101st Annual Meeting of the American Association of Cancer Research (AACR).

9 Apr 2010

Drugs that affect methylation state of genes could reverse autism's effects: The FASEB Journal

A new discovery raises hope that autism may be more easily diagnosed and that its effects may be more reversible than previously thought. In a new study appearing online in The FASEB Journal, scientists have identified a way to detect the disorder using blood and have discovered that drugs which affect the methylation state of genes could reverse autism's effects.

9 Apr 2010

Non-psychoactive cannabis to be unveiled at Annual National Clinical Conference on Cannabis Therapeutics

The availability of a new type of medical cannabis strain will be presented for the first time by Steve DeAngelo, who has been featured on CNN, The Wall Street Journal, Fortune Magazine, and The New York Times as Executive Director of one of the nation's top model and non-profit medical cannabis dispensaries, Harborside Health Center in Oakland, California.

9 Apr 2010

Magnetic targeting may enhance effectiveness of stem cell therapies for heart injuries

Researchers at the Cedars-Sinai Heart Institute have found in animals that infusing cardiac-derived stem cells with micro-size particles of iron and then using a magnet to guide those stem cells to the area of the heart damaged in a heart attack boosts the heart's retention of those cells and could increase the therapeutic benefit of stem cell therapy for heart disease.

9 Apr 2010

Stimulating care homes can help people living with dementia

New research by Kingston University has revealed how design can improve the quality of life for people with dementia. The University hopes the new study will form a blueprint for future building, lay-out and management of care homes.

9 Apr 2010

Independent management of diabetes a huge issue for teens

It is hard enough being a teenager − or the parent of a teenager − without also having to deal with type 1 diabetes. Keeping good control can be a problem when the responsibility for administering insulin and checking blood glucose levels passes from parent to child.

9 Apr 2010

Scientist develops SAMON system to diagnose apnea-hypopnea sleep syndrome

The sleep study or test is key for diagnosing apnea-hypopnea syndrome but, given its high cost, few resources are earmarked to it. Computer scientist at the University of the Basque Country, Mr Alfredo Burgos, has presented a thesis that aims to solve this problem.

9 Apr 2010

Recql5 identified as a tumor suppressor in GI tract

Recql5 is a member of the mammalian RecQ helicase family. Genetic mutations that result in loss of RecQ helicase activity give rise to disorders that are associated with cancer predisposition and premature aging, such as Bloom, Werner, and Rothmund-Thomson syndromes. This class of enzymes is best known for their role in maintaining the integrity of the genome to prevent oncogenic mutations.

9 Apr 2010

World's largest autism science and advocacy organization awards 16 new research grants

Autism Speaks, the world's largest autism science and advocacy organization, today announced the awarding of 16 new research grants totaling $5,223,743 over the next three years.

9 Apr 2010

Five-year, $3.7M trial evaluates customized warfarin dosage based on patient genetics

A five-year, $3.7 million clinical trial will investigate how to balance the benefits and risks of warfarin, a drug that helps prevent potentially deadly blood clots.

9 Apr 2010

Omega-3 fatty acids improve nerve regeneration, prevent psychotic disorders and reduce cellular aging

Improving nerve regeneration after corneal surgery, preventing psychotic disorders in those at high risk for them and reducing cellular aging are three emerging benefits of the omega-3 fatty acids found in seafood, according to milestone research described in the April 2010 PUFA Newsletter and Fats of Life online publications for health professionals and consumers, respectively.

9 Apr 2010

Obese adolescents sleep less

Obese adolescents go to bed later and sleep less than their lighter contemporaries. This is the finding of a study published in the April issue of Australian and New Zealand Journal of Public Health.

9 Apr 2010

Mayo Clinic Health Letter: UV light slows skin cell overgrowth, alters immune system

Ultraviolet light -- a culprit behind sunburns, wrinkles and skin cancer -- offers benefits for some skin conditions, according to the April issue of Mayo Clinic Health Letter.

9 Apr 2010

No link between dyslexia and lack of musical ability

There is no link between a lack of musical ability and dyslexia. Moreover, attempts to treat dyslexia with music therapy are unwarranted, according to scientists in Belgium writing in the current issue of the International Journal of Arts and Technology.

9 Apr 2010

Biosense Webster obtains first Ethics Committee approval for CLARITY study

Biosense Webster announces that this week it has obtained its first Ethics Committee approval for the CLARITY study, comparing the 1-year efficacy, safety and efficiency of CARTO(R) 3 System-guided radiofrequency ablation using the NAVISTAR(R) THERMOCOOL(R) Catheter versus fluoroscopy-guided radiofrequency ablation using the Pulmonary Vein Ablation Catheter(R) (PVAC(R), Ablation Frontiers, Medtronic) in patients with paroxysmal atrial fibrillation.

9 Apr 2010

Researchers show iRGD peptide increases treatment efficacy against cancer

Researchers have shown that a peptide (a chain of amino acids) called iRGD helps co-administered drugs penetrate deeply into tumor tissue. The peptide has been shown to substantially increase treatment efficacy against human breast, prostate and pancreatic cancers in mice, achieving the same therapeutic effect as a normal dose with one-third as much of the drug.

9 Apr 2010

"Nanovaccine" reverses diabetes

A new study, published online April 8 by Cell Press in the journal Immunity, describes a unique therapeutic "nanovaccine" that successfully reverses diabetes in a mouse model of the disease. In addition to providing new insight into diabetes, the research also reveals an aspect of the pathogenesis of the autoimmune response that may provide a therapeutic strategy for multiple autoimmune disorders.

9 Apr 2010

Happy marriage may help prevent fatal strokes in men: Study

"Love and marriage," sang philosopher Frank Sinatra, "is an institute you can't disparage." Especially, a new Tel Aviv University study suggests, when a happy marriage may help to prevent fatal strokes in men.

9 Apr 2010

PESA CNIC-Santander trial initiative to increase knowledge about cardiovascular diseases

Felipe P-triz, Secretary of State for Research and Emilio Bot-n, President of the Grupo Santander, signed today a milestone agreement giving birth to the PESA (Progression of Early Subclinical Atherosclerosis) CNIC-Santander trial. The project's main goal is to increase the knowledge about cardiovascular diseases.

9 Apr 2010

Medical Condition News

Gelatinase B expression enhanced in gastric cancer compared to normal gastric mucosa

Mayo Clinic researchers to present XOMA 052 data at 101st AACR Annual Meeting

Drugs that affect methylation state of genes could reverse autism's effects: The FASEB Journal

Non-psychoactive cannabis to be unveiled at Annual National Clinical Conference on Cannabis Therapeutics

Magnetic targeting may enhance effectiveness of stem cell therapies for heart injuries

Stimulating care homes can help people living with dementia

Independent management of diabetes a huge issue for teens

Scientist develops SAMON system to diagnose apnea-hypopnea sleep syndrome

Recql5 identified as a tumor suppressor in GI tract

World's largest autism science and advocacy organization awards 16 new research grants

Five-year, $3.7M trial evaluates customized warfarin dosage based on patient genetics

Omega-3 fatty acids improve nerve regeneration, prevent psychotic disorders and reduce cellular aging

Obese adolescents sleep less

Mayo Clinic Health Letter: UV light slows skin cell overgrowth, alters immune system

No link between dyslexia and lack of musical ability

Biosense Webster obtains first Ethics Committee approval for CLARITY study

Researchers show iRGD peptide increases treatment efficacy against cancer

"Nanovaccine" reverses diabetes

Happy marriage may help prevent fatal strokes in men: Study

PESA CNIC-Santander trial initiative to increase knowledge about cardiovascular diseases

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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