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Altheos to fund development of ATS907 Rho-kinase inhibitor with completed $20M Series A financing

Altheos, Inc., a privately held early-stage biopharmaceutical company, announced today that it has completed a $20 million Series A financing led by Bay City Capital. New investors Novo A/S, Canaan Partners, Life Science Angels and Atheneos Capital also joined the round. The financing will be used primarily for the development of ATS907, a selective Rho-kinase inhibitor Altheos licensed from Japanese pharmaceutical company Asahi Kasei Pharma. The license also includes a series of highly active compounds (AK138 series) specifically for topical treatment for glaucoma.

5 Apr 2010

Juventas Therapeutics commences enrollment in Phase I trial of JVS-100 for treatment of Class III heart failure

Juventas Therapeutics, a privately held, clinical-stage regenerative medicine company announced it has started enrolling patients in a Phase I clinical trial for JVS-100 to evaluate safety and efficacy in the treatment of patients with Class III heart failure. JVS-100 encodes Stromal Cell-derived Factor-1 (SDF-1) and has been shown in pre-clinical studies to significantly increase cardiac function by promoting cell survival and increasing new blood vessel formation in the damaged organ.

5 Apr 2010

FDA grants Keryx Biopharmaceuticals Fast Track designation for perifosine

Æterna Zentaris Inc., a late-stage drug development company specialized in oncology and endocrine therapy, today announced that its partner, Keryx Biopharmaceuticals, was granted Fast Track designation by the U.S. Food and Drug Administration for perifosine (KRX-0401), the Company's novel, potentially first-in-class, oral anti-cancer agent that inhibits the phosphoinositide 3-kinase (PI3K)/Akt pathway, for the treatment of refractory advanced colorectal cancer.

5 Apr 2010

Individualized therapies for treating type 2 diabetes recommended

Chevy Chase, MD-Patients with type 2 diabetes are generally treated similarly despite the fact that they may have underlying differences that could affect their therapeutic response. Seeking to address this critical health issue, an international multidisciplinary group of experts just issued recommendations for individualized treatment in a consensus statement to be published in the April 2010 issue of the Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM).

5 Apr 2010

Economic burden associated with HAE treatment: First-ever comprehensive examination

Dyax Corp. announced the publication of a first-ever comprehensive examination of the economic burden associated with the treatment of acute attacks and chronic management of hereditary angioedema (HAE). The results, published today in the Annals of Allergy, Asthma, and Immunology, bring to light the substantial direct and indirect medical costs of the disease on patients, payers and society. The economic study is one component of a larger survey-based Burden of Illness (BOI) study which assessed both the economic and humanistic burden of HAE.

5 Apr 2010

LCA-Vision reports 19,066 procedures performed during first-quarter 2010

LCA-Vision Inc., a leading provider of laser vision correction services under the LasikPlus® brand, today reported that 19,066 procedures were performed during the first quarter of 2010. This compares with 27,859 procedures (75 vision centers) and 25,232 same-store procedures (62 vision centers) performed during the first quarter of 2009.

5 Apr 2010

Disability Leadership and Policy Summit to be hosted in Philadelphia, Pennsylvania

United Spinal Association will host its inaugural Disability Leadership and Policy Summit on April 15th in Philadelphia, commemorating the 20th Anniversary of the Americans with Disabilities Act, which was signed into law on July 26, 1990 and prohibits discrimination based on disability. The law was amended in 2008 to offer more protection to disabled workers.

5 Apr 2010

Johns Hopkins Kimmel Cancer Center reviews top cancer stories

Surgeon Jeremy Richmon, M.D., at Johns Hopkins is using robotic assistance to cut away tumors of the tongue and tonsils. Conventional surgery leaves disfiguring neck and jaw scars, but the robotic procedure leaves no scar except for inside the mouth, and he says, patients retain good function of speech and swallowing.

5 Apr 2010

A1C test for diagnosing diabetes must be reevaluated: Journal of Diabetes

As a benchmark for diagnosing diabetes, the importance of the A1C test must be reevaluated to improve glycemic numeracy of policy makers, patients and providers - who must make real-world decisions. This is based on a commentary published by Wiley-Blackwell in the Journal of Diabetes.

5 Apr 2010

Opexa Therapeutics to discuss on personalized medicine for treatment of MS

Opexa Therapeutics, Inc., a company developing a novel T-cell therapy for multiple sclerosis, announced today that the company will participate in a panel discussion on Personalized Medicine for the Treatment of Multiple Sclerosis on April 7, 2010.

5 Apr 2010

Is relief round the corner for multiple sclerosis patients in the form of bee stings?

A recent development can raise the hopes of many sufferers of Multiple Sclerosis (MS) – a dreaded, debilitating, fatal nerve disorder. Charity worker Sami Chugg, 45, claims to have overcome her condition after being stung by bees.

5 Apr 2010

Diabetic tests must be regulated

As a benchmark for diagnosing diabetes, the importance of the A1C test must be reevaluated to improve glycemic numeracy of policy makers, patients and providers – who must make real-world decisions. This is based on a commentary published by Wiley-Blackwell in the Journal of Diabetes.

5 Apr 2010

Research may help develop new ways to diagnose and treat communication disorders

An international research consortium has identified more than 800 genes that appear to play a role in the male zebra finch's ability to learn elaborate songs from his father. The researchers also found evidence that song behavior engages complex gene regulatory networks within the brain of the songbird- networks that rely on parts of the genome once considered junk.

5 Apr 2010

Study refutes widely held belief that intentional weight loss in older adults leads to increased risk of death

A new study by researchers at Wake Forest University Baptist Medical Center is the first to refute the widely held belief that intentional weight loss in older adults leads to increased risk of death.

5 Apr 2010

Researchers identify three new genetic variants that increase risk of intracranial aneurysms

In the largest genome-wide study of brain aneurysms ever conducted, an international team led by researchers at the Yale School of Medicine have identified three new genetic variants that increase a person's risk for developing this deadly disease.

5 Apr 2010

KMI receives 2-year Phase II SBIR grant to study new treatment for TBI

Kinetic Muscles Inc., a leading innovator of neurorehabilitation technology, announced it has received a 2-year Phase II SBIR grant to study a new treatment for veterans returning from active duty with traumatic brain injury.

5 Apr 2010

Some therapies being investigated for Alzheimer's disease may cause cell death: UCSD

Some current therapies being investigated for Alzheimer's disease may cause further neural degeneration and cell death, according to a breakthrough discovery by UC San Diego researchers. By combining three dimensional computer simulations with high resolution atomic force microscopy membrane protein and cell imaging, electrical recording and various cellular assays, UCSD nano-biophysicist Ratnesh Lal and his colleagues investigated the structure and function of truncated peptides, known as nonamyloidgenic peptides, formed by some Alzheimer's drug candidates.

5 Apr 2010

UEA scientists discover group of molecules that can help fight spread of cancer

A team of scientists led by the University of East Anglia has discovered a brand new group of molecules which could help fight the spread of cancer and other diseases.

5 Apr 2010

SRI director on importance of seeking treatment for sex addiction

Following rumours that Jesse James has checked into rehab for sex addiction, Robert Weiss, LCSW, CSAT-S, founding director of the Sexual Recovery Institute, today issued the following statement to explain how simple pleasure oriented behaviours can evolve into addiction and the importance of seeking treatment.

3 Apr 2010

Clinical utility and pharmacological action of MN-166 in treatment of MS

MediciNova, Inc, a biopharmaceutical company publicly traded on the Nasdaq Global Market and the Hercules Market of the Osaka Securities Exchange, today reported that this week's issue of Neurology includes two articles related to the potential clinical utility and unique pharmacological action of MN-166 in treating multiple sclerosis (MS).

3 Apr 2010

Medical Condition News

Altheos to fund development of ATS907 Rho-kinase inhibitor with completed $20M Series A financing

Juventas Therapeutics commences enrollment in Phase I trial of JVS-100 for treatment of Class III heart failure

FDA grants Keryx Biopharmaceuticals Fast Track designation for perifosine

Individualized therapies for treating type 2 diabetes recommended

Economic burden associated with HAE treatment: First-ever comprehensive examination

LCA-Vision reports 19,066 procedures performed during first-quarter 2010

Disability Leadership and Policy Summit to be hosted in Philadelphia, Pennsylvania

Johns Hopkins Kimmel Cancer Center reviews top cancer stories

A1C test for diagnosing diabetes must be reevaluated: Journal of Diabetes

Opexa Therapeutics to discuss on personalized medicine for treatment of MS

Is relief round the corner for multiple sclerosis patients in the form of bee stings?

Diabetic tests must be regulated

Research may help develop new ways to diagnose and treat communication disorders

Study refutes widely held belief that intentional weight loss in older adults leads to increased risk of death

Researchers identify three new genetic variants that increase risk of intracranial aneurysms

KMI receives 2-year Phase II SBIR grant to study new treatment for TBI

Some therapies being investigated for Alzheimer's disease may cause cell death: UCSD

UEA scientists discover group of molecules that can help fight spread of cancer

SRI director on importance of seeking treatment for sex addiction

Clinical utility and pharmacological action of MN-166 in treatment of MS

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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