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New discovery can develop diagnostic test to identify gene mutation in AML

Decoding the DNA of a woman who died of acute myeloid leukemia (AML) has led researchers at Washington University School of Medicine in St. Louis to a gene that they found to be commonly altered in many patients who died quickly of the disease.

11 Nov 2010

Nplate reduces treatment failure and splenectomies in adults with chronic immune thrombocytopenia

Amgen Inc. today announced the publication of results from the first open-label study to compare Nplate® (romiplostim) treatment to standard of care therapies (SOC) in non-splenectomized adult patients with chronic immune thrombocytopenia (ITP). The study results, which were published today in the New England Journal of Medicine (NEJM), show that both the incidence of treatment failure and need for splenectomy were reduced among the Nplate-treated patients.

11 Nov 2010

Watson’s Uracyst pilot study for interstitial cystitis fails to demonstrate efficacy endpoints

Watson Pharmaceuticals, Inc. today announced that the U.S. pilot study evaluating Uracyst (sodium chondroitin sulfate solution 2.0%) for the treatment of interstitial cystitis did not meet predefined efficacy endpoints.

11 Nov 2010

Dietary intervention reduces emergence of diabetes-predictive autoantibodies by 50%

A Finnish study published in the November 11, 2010 issue of the New England Journal of Medicine confirms the hypothesis that infant feeding plays a role in the initiation of the disease process leading to type 1 diabetes in children carrying increased genetic disease risk.

11 Nov 2010

Study suggests mid-life cholesterol level may not linked to later development of Alzheimer's disease

Contrary to earlier research, a new, long-term study suggests that cholesterol level in mid-life may not be linked to later development of Alzheimer's disease, according to a study published in the November 10, 2010, online issue of Neurology, the medical journal of the American Academy of Neurology. However, the results suggest that large decreases in cholesterol levels in old age could be a better predictor of developing the memory-robbing disease.

11 Nov 2010

New 'magic bullet' can eradicate side effects of drug used to treat cystinosis

A 'magic bullet' designed by pharmaceutical scientists at an English university could eradicate the side effects of a drug used to treat a rare genetic disease. Researchers at the University of Sunderland have chemically modified a drug used to treat cystinosis a disease which occurs when the body's mechanism to remove excess cystine (an amino acid) breaks down, leading to kidney problems and eventually affecting other organs to remove unpleasant side effects such as nausea, vomiting, severe halitosis, body odour and a noxious taste.

11 Nov 2010

Depression associated with molecular-level disturbance in body's 24-hour clock

Depression appears to be associated with a molecular-level disturbance in the body's 24-hour clock, new research suggests.

11 Nov 2010

Spinal Column: New blog on spinal disorders

Clinicians seeking insight into the latest research on spinal disorders and its impact on their everyday clinical practice will find it in "The Spinal Column," a new weekly blog found on the Spine website. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.

11 Nov 2010

Nutech Mediworld founder presents clinical study results of hESC therapy in patients with spinal cord injury

Dr. Geeta Shroff, founder & medical director of Nutech Mediworld, presented today the summary results of a retrospective clinical study of human embryonic stem cell (hESC) therapy in patients with chronic spinal cord injury (SCI).

11 Nov 2010

SuperGen discontinues clinical development of SGI-1776 PIM kinase drug candidate

SuperGen, Inc. today announced that it has discontinued clinical development of its phase 1 PIM kinase drug candidate, SGI-1776, while continuing development of the PIM inhibitor program.

11 Nov 2010

tDCS electric stimulation can improve motor function in stroke patients

A noninvasive electric stimulation technique administered to both sides of the brain can help stroke patients who have lost motor skills in their hands and arms, according to a new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC).

10 Nov 2010

New stem cell gene, enzyme replacement treatment for Tay-Sachs disease

StemCellRegenMed, Inc. announces that a new stem cell gene and enzyme replacement treatment has been performed on a fourteen month old child with Tay-Sachs disease on November 2, 2010. Tay-Sachs is a devastating disease that afflicts children primarily of parents of Jewish heritage and in very rare cases families of Eastern European background and the Cajun region in the U.S.A.

10 Nov 2010

Antigen Express awarded Therapeutic Discovery Project grants for cancer vaccine development

Generex Biotechnology Corporationannounced today that its wholly-owned immunotherapeutics subsidiary, Antigen Express, Inc. has been awarded two Therapeutic Discovery Project grants, totaling $488,958.50, by the United States Internal Revenue Service (IRS) and the Department of Health and Human Services (HHS) pursuant to the Patient Protection and Affordable Care Act of 2010.

10 Nov 2010

Epimutation in BRCA1 gene may cause early-onset of breast cancer

An Australian research team from the Peter MacCallum Cancer Centre, the University of Melbourne and the University of Queensland has identified a new risk factor for developing breast cancer. This has been published online in the journal Cancer Prevention Research.

10 Nov 2010

Gentium to present three abstracts on Defibrotide at American Society of Hematology

Gentium S.p.A. today announced that three abstracts on Defibrotide will be presented at the 52nd Annual Meeting and Exposition of the American Society of Hematology to be held at the Orange County Convention Center in Orlando, Florida, December 4-7, 2010.

10 Nov 2010

Dementia deaths & incidence on the rise

A new report highlights the fact that one in six deaths are caused by dementia in England. The report looked at death certificates between 2001 and 2009 and found that conditions such as Alzheimer’s disease account for 15 per cent of deaths in England. Two-thirds of victims died in nursing or residential care homes and a third in hospital. Most campaigners claim that the actual figures may be higher and put it as one in three deaths. The report also says that the total number of deaths due to dementia are rising.

10 Nov 2010

Simple test and an MRI predicts future Alzheimer’s disease

Until now is has been believed that Alzheimer’s disease and other forms of dementia could be diagnosed only when symptoms appear which almost always means when patients are in their 70s or 80s. Now the latest research shows that some brain lesions are characteristic of Alzheimer’s disease and can be detected in the brains of healthy people in their 40s. Along with this a simple mental skills test may be able to detect the problem many years sooner than previously thought.

10 Nov 2010

Positive results from XOMA 052 study in patients with uveitis of Behcet's disease

XOMA Ltd., a leader in the discovery and development of therapeutic antibodies, announced additional positive results from an open-label pilot study of XOMA 052 in patients with uveitis of Behcet's disease who were suffering from vision-threatening exacerbations despite maximal doses of immunosuppressive medicines.

10 Nov 2010

China Medical Technologies' EGFR PCR Assay for lung cancer targeted drugs receives Chinese SFDA approval

China Medical Technologies, Inc., a leading China-based advanced in-vitro diagnostic ("IVD") company, today announced that it has received approval for its real-time PCR-based Epidermal Growth Factor Receptor Assay (the "EGFR PCR Assay") for the use of lung cancer targeted drugs from the State Food and Drug Administration of China (the "SFDA").

10 Nov 2010

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Using proton pump inhibitors and antiplatelet drugs (thienopyridines) together is an appropriate way of treating patients with cardiovascular disease who are at high risk of upper gastrointestinal bleeds, despite recent concerns about an adverse interaction between these two types of drugs, according to an Expert Consensus Document released jointly today by the American College of Cardiology Foundation, the American College of Gastroenterology, and the American Heart Association.

10 Nov 2010

Medical Condition News

New discovery can develop diagnostic test to identify gene mutation in AML

Nplate reduces treatment failure and splenectomies in adults with chronic immune thrombocytopenia

Watson’s Uracyst pilot study for interstitial cystitis fails to demonstrate efficacy endpoints

Dietary intervention reduces emergence of diabetes-predictive autoantibodies by 50%

Study suggests mid-life cholesterol level may not linked to later development of Alzheimer's disease

New 'magic bullet' can eradicate side effects of drug used to treat cystinosis

Depression associated with molecular-level disturbance in body's 24-hour clock

Spinal Column: New blog on spinal disorders

Nutech Mediworld founder presents clinical study results of hESC therapy in patients with spinal cord injury

SuperGen discontinues clinical development of SGI-1776 PIM kinase drug candidate

tDCS electric stimulation can improve motor function in stroke patients

New stem cell gene, enzyme replacement treatment for Tay-Sachs disease

Antigen Express awarded Therapeutic Discovery Project grants for cancer vaccine development

Epimutation in BRCA1 gene may cause early-onset of breast cancer

Gentium to present three abstracts on Defibrotide at American Society of Hematology

Dementia deaths & incidence on the rise

Simple test and an MRI predicts future Alzheimer’s disease

Positive results from XOMA 052 study in patients with uveitis of Behcet's disease

China Medical Technologies' EGFR PCR Assay for lung cancer targeted drugs receives Chinese SFDA approval

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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