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Trubion Pharmaceuticals to present promising data from Phase 1 studies of SBI-087, SBI-087

Trubion Pharmaceuticals, Inc. today announced the acceptance of two Phase 1 data presentations on SBI-087 (PF-05230895) at the 2010 annual congress of the European League Against Rheumatism (EULAR) in Rome, Italy. Presentations will include promising data from a Phase 1 study of SBI-087 for the treatment of rheumatoid arthritis (RA) and a Phase 1 study of SBI-087 for the treatment of systemic lupus erythematosus (SLE). Copies of both abstracts are available at http://www.eular.org. SBI-087 is Trubion's next-generation CD20-directed small modular immunopharmaceutical (SMIP™) product candidate and is being developed in collaboration with Pfizer.

13 May 2010

Cancer Research UK to unveil its eighth garden at Chelsea Flower Show 2010

Cancer Research UK will unveil its eighth garden at Chelsea Flower Show 2010 (25 - 29 May 2010), designed for the second year running by four-time gold medal winner, Robert Myers.

13 May 2010

Research investigates MDR in human HCC

Hepatocellular carcinoma responds poorly to chemotherapy owing to MDR. Recent studies have shown the tumors derived from the colon, kidney, or adrenal cortex, and HCC exhibited overexpression of MDR1/P-gp. This overexpression results in a primary MDR phenotype of these cancers.

13 May 2010

Cognitive strategies lessen depression symptoms: Study

Moderate to severely depressed clients showed greater improvement in cognitive therapy when therapists emphasized changing how they think rather than how they behave, new research has found.

13 May 2010

Researchers to discuss various implications for personalized medicine during one-day symposium

On May 27, researchers with the National Human Genome Research Institute and the National Cancer Institute, along with Group Health Cooperative in Seattle and Henry Ford Health System, will debate and discuss that question during the one-day symposium "Multiplex Initiative: Implications for Personalized Medicine."

13 May 2010

Children and young adults account for as many as 10% of all stroke cases

The news that Vice President Joe Biden's 41-year-old son has suffered a stroke is highlighting the problem of strokes in young people.

13 May 2010

27-year-old sickle cell disease patient undergoes multiple joint replacement surgery

Fortis Hospitals Mulund, Mumbai, performed a multiple joint replacement surgery on a 27 year old young Nigerian patient. Rebacca underwent a hip and a shoulder replacement surgery by Dr. Sachin Bhonsle, Consultant Orthopedic Surgeon, after years of suffering in pain and immobility.

13 May 2010

Rapid responders in novel behavior treatment for IBS maintain improvement at 3-month follow-up

Nearly one-third of patients with irritable bowel syndrome (IBS) who underwent a novel behavior treatment developed by a University at Buffalo behavioral scientist achieved significant relief within four weeks of beginning treatment.

13 May 2010

RYGB surgery increases insulin activity in diabetes mellitus patients

Diabetes mellitus is a chronic metabolic disease resulted from, either decreased production of insulin or increased resistance to it from peripheral tissues or both factors combined together. While medical treatment remains the mainstay of treatment for diabetes, some surgical procedures, such as Roux-en-Y gastric bypass, have demonstrated some potential to be a treatment option for diabetes.

13 May 2010

Childhood sexual or emotional abuse associated with greater body dissatisfaction in BED: JGH

Imagine stuffing yourself with a day's worth of food in two hours or less. Imagine feeling disgusted, depressed and guilty once you finally stop. Then imagine doing it again, repeatedly and uncontrollably, once a week or more for months on end.

13 May 2010

Researchers develop new approach to immunotherapy of cancer

Harnessing the immune system is emerging as one of the most promising new ways to fight cancer. Most cancer cells are eliminated by the immune system; however, over a lifetime, a few may escape this immune surveillance and lead to tumors and metastases. Hence a formidable opportunity has been to find ways to make the immune system recognize the tumor as a foreign body and trigger a response.

13 May 2010

e-Volution-TREAT system simplifies mental health care planning in Ontario and beyond

Mental health, the second leading cause of disability and premature death in Canada, impacts the lives of every Canadian, much like technology. Mental health and technology are now being brought together with an innovative tool developed by University of Toronto Bloomberg nursing researchers in collaboration with Toronto-based software development company HInext and the Centre for Addiction and Mental Health.

13 May 2010

Music enhances new learning of information in AD patients

Researchers from Boston University School of Medicine (BUSM) have shown that patients with Alzheimer's disease (AD) are better able to remember new verbal information when it is provided in the context of music even when compared to healthy, older adults. The findings, which currently appear on-line in Neuropsychologia, offer possible applications in treating and caring for patients with AD.

13 May 2010

Robotic surgery keeps features intact in head, neck cancer removal procedures

Surgeons who perform procedures to remove head and neck cancers often work for six to eight hours on what is typically major, invasive surgery, which many times comes with facial disfigurement and debilitating side effects for the patient.

13 May 2010

Study: When incentive payments are removed, quality of health care suffers

Los Angeles Times: Researchers in Britain teamed with Kaiser Permanente in Northern California "to see what happened in Northern California when the health giant stopped rewarding doctors who screened patients for diabetic retinopathy and cervical cancer."

13 May 2010

Four caged xanthones can inhibit growth of CCA cell lines: Research article

Cholangiocarcinoma is a malignant tumor, characterized by a poor prognosis and unresponsive to conventional chemotherapeutic agents. Therefore, searching for novel and effective therapeutic agents for CCA is necessary. In previous studies, several caged xanthones from G. hanburyi have been reported to be potent antiproliferatives as well as having anticancer and anti-tumor activities and they induce apoptosis in various cancer cell lines.

13 May 2010

Study compares outcome of popular esophageal stents in patients with dysphagia

Less than 50% of patients with esophageal carcinoma are suitable for surgery at the time of diagnosis. Most of these patients present with locally advanced or metastatic disease and/or significant comorbidities. In such circumstances, the only therapeutic option is palliative care to treat dysphagia and prevent respiratory complications secondary to aspiration. Self-expanding metal stents have been proven effective for palliation of dysphagia in patients with esophageal carcinoma, tracheo-esophageal fistulas or anastomotic leaks.

13 May 2010

Individual's lifestyle choices can affect cholesterol, triglycerides levels: Mayo Clinic Health Letter

Diet and lifestyle choices aren't only evident on the bathroom scale. The effect of these choices is also reflected with relative accuracy in cholesterol numbers.

13 May 2010

Additional benefits of LAIAs over long-acting human insulin not been proven

It has so far not been proven that the long-acting insulin analogues (LAIAs) insulin detemir (trade name: Levemir) and insulin glargine (trade name: Lantus), which are approved for the treatment of type 1 diabetes, offer patients an additional benefit versus long-acting human insulin. This applies to adults as well as to children and adolescents. This is the result of the final report published by the Institute for Quality and Efficiency in Health Care (IQWiG) on 19 April 2010.

13 May 2010

Study: Treating serious gum disease in diabetics can help lower blood sugar levels

Researchers have found that reducing inflammation of the gums in people with diabetes can help lower the risk of serious complications associated with the condition, such as eye problems and heart disease.

13 May 2010

Medical Condition News

Trubion Pharmaceuticals to present promising data from Phase 1 studies of SBI-087, SBI-087

Cancer Research UK to unveil its eighth garden at Chelsea Flower Show 2010

Research investigates MDR in human HCC

Cognitive strategies lessen depression symptoms: Study

Researchers to discuss various implications for personalized medicine during one-day symposium

Children and young adults account for as many as 10% of all stroke cases

27-year-old sickle cell disease patient undergoes multiple joint replacement surgery

Rapid responders in novel behavior treatment for IBS maintain improvement at 3-month follow-up

RYGB surgery increases insulin activity in diabetes mellitus patients

Childhood sexual or emotional abuse associated with greater body dissatisfaction in BED: JGH

Researchers develop new approach to immunotherapy of cancer

e-Volution-TREAT system simplifies mental health care planning in Ontario and beyond

Music enhances new learning of information in AD patients

Robotic surgery keeps features intact in head, neck cancer removal procedures

Study: When incentive payments are removed, quality of health care suffers

Four caged xanthones can inhibit growth of CCA cell lines: Research article

Study compares outcome of popular esophageal stents in patients with dysphagia

Individual's lifestyle choices can affect cholesterol, triglycerides levels: Mayo Clinic Health Letter

Additional benefits of LAIAs over long-acting human insulin not been proven

Study: Treating serious gum disease in diabetics can help lower blood sugar levels

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

Genomic conservation in Thailand's mangroves

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