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BEMA Granisetron development program: BDSI announces positive meeting with FDA

BioDelivery Sciences International, Inc. announced the positive outcome of a meeting with the FDA on the development program for BEMA Granisetron, the company’s potential treatment for the prevention of nausea and vomiting associated with cancer therapy. FDA concurred with BDSI’s plans to pursue a development program based on clinical pharmacokinetic data for a 505(b)(2) New Drug Application.

22 Mar 2010

ChemoCentryx undertakes Phase II clinical trial of CCX140

ChemoCentryx, Inc., today announced that it has undertaken a Phase II clinical trial of CCX140, a novel, orally-available small molecule compound designed to specifically target the chemokine receptor known as CCR2.

22 Mar 2010

Bakeries across the U.S. join campaign for epilepsy awareness

This week, bakeries across the United States are cooking up purple cupcakes in an effort to increase awareness about epilepsy nationwide. The Great Purple Cupcake Project is an initiative of The Anita Kaufmann Foundation -- an American epilepsy education organization and the US Sponsor of Purple Day for epilepsy awareness.

22 Mar 2010

First patient dosed in NCI-sponsored Phase 1/2 trial of belinostat

Spectrum Pharmaceuticals, Inc., a commercial-stage biotechnology company with a primary focus in oncology and hematology, and TopoTarget A/S, today announced that the first patient has been dosed in a National Cancer Institute -sponsored Phase 1/2 trial of belinostat in combination with cisplatin, doxorubicin and cyclophosphamide in the first line treatment of advanced or recurrent thymic malignancies.

22 Mar 2010

Dow Jones reports on side effects of Labopharm's once-daily version of Trazodone, stock falls by 5%

After Canadian specialty pharmaceutical company Labopharm received FDA approval for its once-daily version of antidepressant Trazodone, Dow Jones Newswires reported that it will be difficult to convince prescribers to switch from less expensive generic versions. Dow Jones found that when compared, the side effects of Labopharm's drug fare no better than the generic versions that dominate the market.

22 Mar 2010

Americans to join in Purple Day campaign to support epilepsy awareness

Members of the U.S. House and Senate, children in schools across the country, and employees of workplaces nationwide will wear purple to support epilepsy awareness on March 26. Thousands of Americans will also join the campaign by hosting Purple Day activities in their regions.

22 Mar 2010

Calando Pharmaceuticals demonstrates first targeted siRNA-containing nanoparticle delivery to tumors

Arrowhead Research Corporation today announced that the clinical trial being conducted by majority-owned subsidiary, Calando Pharmaceuticals, Inc., has demonstrated systemic delivery of siRNA and the successful “silencing” of a widely recognized cancer gene via RNA interference (RNAi) in humans.

22 Mar 2010

Simcere Pharmaceutical completes Phase IV clinical study of Endostar

Simcere Pharmaceutical Group, a leading manufacturer and supplier of branded generic pharmaceuticals and manufacturer of the patented anti-cancer biotech product Endostar (also known as Endu) in China, announced today the successful completion of Endostar Phase IV clinical study at a conference in Beijing dedicated to this study.

22 Mar 2010

FDA convenes Advisory Committee meeting to discuss safety of LABA's

On Wednesday, March 10 and Thursday, March 11, the FDA is convening an Advisory Committee meeting on the clinical trial design for long acting beta-2 adrenergic agonists.

22 Mar 2010

Gene implicated in JSRDs: UCD research team publishes new information

Researchers in University College Dublin (UCD) led by Conway Fellow, Dr Oliver Blacque have revealed new information about a gene implicated in Joubert syndrome and related cerebellar disorders (JSRDs) that are characterised by blindness, bone abnormalities, cystic kidneys, developmental delay and loss of muscle tone and control. The findings from this research, which is funded by Science Foundation Ireland, have been published today in a leading science journal, Journal of Cell Biology.

22 Mar 2010

Cancer radiotherapy can increase risk of cardiovascular disease later in life

For an as yet unknown reason, cancer radiotherapy can increase the risk of cardiovascular disease later in life, a problem that is growing as more and more people survive their cancer diagnosis. New research from Karolinska Institutet now suggests that sustained inflammation induced by post-radiotherapy changes in the gene expression in the arteries could be the cause.

22 Mar 2010

Own blood plasma injection may provide relief for tendinopathy, where traditional treatment fails

When tendon trouble -- such as tennis elbow or Achilles tendon pain -- doesn’t respond to traditional treatment, an injection of the patient’s own blood plasma into the tendon may provide relief.

22 Mar 2010

No significant racial differences in cancer patient mortality rates: Study

A new study has found that when African American and white cancer patients are treated at similar, specialized cancer care institutions, mortality rates are roughly equal. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the findings suggest that where patients receive care may partly explain observed racial disparities in cancer mortality.

22 Mar 2010

Primary care physicians agree on responsibility in addressing obesity, but lack right weight management resources

Primary care physicians agree they have a role in addressing obesity, but say they do not have the right weight management resources. Obese or heavier adults take responsibility for weight loss, but adults who need to lose weight may lack information about effective weight loss methods and strategies. These findings and others come from new research commissioned and released today by the Strategies to Overcome and Prevent (STOP) Obesity Alliance, a project operating out of the Department of Health Policy at The George Washington University School of Public Health and Health Services.

22 Mar 2010

Formatech selects Tracon Pharmaceuticals’ TRC102 inhibitor as next Fillanthropy Program candidate

Today, Formatech, Inc. announces the selection of Tracon Pharmaceuticals’ TRC102 clinical product as the next Fillanthropy™ Program candidate. Under this program, Formatech donates the services required to aseptically fill and finish one lot of the drug candidate to support Tracon’s upcoming clinical trials.

22 Mar 2010

Natural fibre in sea kelp may help tackle obesity

Seaweed could hold the key to tackling obesity after it was found it reduces fat uptake by more than 75 per cent, new research has shown.

22 Mar 2010

Asuragen appoints BMD as exclusive distributor of Signature Oncology Products in France

Asuragen, Inc., a leader in the development of molecular diagnostics, announced today the appointment of Biomedical Diagnostics SA, a leading medical diagnostic company in Europe, as its exclusive distributor of Signature® Oncology Products in France. Asuragen’s Signature Oncology Portfolio comprises multiplex assays for the detection of mutations in solid and hematologic malignancies.

22 Mar 2010

Male infertility linked to increased risk of high grade prostate cancer

Infertile men have an increased risk of developing high grade prostate cancer, which is more likely to grow and spread quickly. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The study's results suggest that because infertility may be an identifiable risk factor for prostate cancer, early screening may be warranted in infertile men.

22 Mar 2010

HAIs in southeast U.S. community hospitals: Infection rates for CDI surpass MRSA's

Researchers studying epidemiology of healthcare-associated infections in community hospitals in the southeast U.S. found that rates of Clostridium difficile infections (CDI) surpassed infection rates for methicillin-resistant Staphylococcus aureus (MRSA). Scientists also discovered that healthcare-associated CDI, which is a bacterium that causes diarrhea and more serious intestinal conditions such as colitis, occurs more often (21 percent) than healthcare-associated infections due to MRSA.

22 Mar 2010

Mayo Clinic co-led research finds first gene linked to lung cancer in "never smokers"

A five-center collaborative study that scanned the genomes of thousands of "never smokers" diagnosed with lung cancer as well as healthy never smokers has found a gene they say could be responsible for a significant number of those cancers.

22 Mar 2010

Medical Condition News

BEMA Granisetron development program: BDSI announces positive meeting with FDA

ChemoCentryx undertakes Phase II clinical trial of CCX140

Bakeries across the U.S. join campaign for epilepsy awareness

First patient dosed in NCI-sponsored Phase 1/2 trial of belinostat

Dow Jones reports on side effects of Labopharm's once-daily version of Trazodone, stock falls by 5%

Americans to join in Purple Day campaign to support epilepsy awareness

Calando Pharmaceuticals demonstrates first targeted siRNA-containing nanoparticle delivery to tumors

Simcere Pharmaceutical completes Phase IV clinical study of Endostar

FDA convenes Advisory Committee meeting to discuss safety of LABA's

Gene implicated in JSRDs: UCD research team publishes new information

Cancer radiotherapy can increase risk of cardiovascular disease later in life

Own blood plasma injection may provide relief for tendinopathy, where traditional treatment fails

No significant racial differences in cancer patient mortality rates: Study

Primary care physicians agree on responsibility in addressing obesity, but lack right weight management resources

Formatech selects Tracon Pharmaceuticals’ TRC102 inhibitor as next Fillanthropy Program candidate

Natural fibre in sea kelp may help tackle obesity

Asuragen appoints BMD as exclusive distributor of Signature Oncology Products in France

Male infertility linked to increased risk of high grade prostate cancer

HAIs in southeast U.S. community hospitals: Infection rates for CDI surpass MRSA's

Mayo Clinic co-led research finds first gene linked to lung cancer in "never smokers"

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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