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Actemra: 38% of rheumatologists have commenced treatment

BioTrends Research Group released topline findings from LaunchTrends®: ACTEMRA, Wave 1 today, highlighting the market uptake of the product at one month post launch. Actemra (tocilizumab), marketed by Roche-Genentech, is a new IL-6 inhibitor with monthly dosing by IV infusion. The study results are based on an on-line survey completed by 77 rheumatologists in late February.

3 Mar 2010

Pfizer, Medivation announce results of two dimebon Phase 3 trials in AD patients

Pfizer Inc. and Medivation, Inc. today announced results from two Phase 3 trials of the investigational drug dimebon (latrepirdine) in patients with Alzheimer’s disease (AD). In the CONNECTION trial, dimebon did not meet its co-primary or secondary efficacy endpoints compared to placebo. Co-primary endpoints were measures of cognition and global function.

3 Mar 2010

Spectral Diagnostics receives FDA IDE approval for Toraymyxin

BioMS Medical Corp. today reported that Spectral Diagnostics has received Investigational Device Exemption (IDE) approval from the U.S. Food and Drug Administration (FDA) for Toraymyxin(TM). Spectral Diagnostics and BioMS have entered into a services agreement whereby BioMS will assist Spectral, as required, in its commercialization of Toraymyxin(TM), a therapeutic hemoperfusion device for the treatment of severe sepsis. This approval permits Spectral to initiate its planned pivotal trial for Toraymyxin(TM) in the United States.

3 Mar 2010

Gene 'addiction' of leukaemia cells

An international team of scientists studying acute forms of Leukaemia have identified a new drug target to inhibit the genes which are vital for the growth of diseased cells. The research, reported in EMBO Molecular Medicine, reveals how leukaemia cells become 'addicted' to genes, which if targeted could prevent diseased cells from developing.

3 Mar 2010

Pennsylvania makes available $400,000 in federal fund to support individuals within criminal justice system

Pennsylvania is making available $400,000 in federal American Recovery and Reinvestment Act funds to provide certified forensic peer support services to individuals within the criminal justice system who are suffering from mental illness, as well as psychiatric and substance abuse disorders.

3 Mar 2010

Allergan celebrates 20th anniversary of BOTOX in Canada

Twenty years ago, the first approved use of BOTOX(R) (botulinum toxin type A), a neurotoxin widely used to treat several life altering medical conditions, was granted in Canada. As part of the 20th anniversary celebrations, healthcare professionals from coast to coast reflect upon the discovery, science and evolution of a therapy that has impacted the lives of millions of patients worldwide.

3 Mar 2010

Seattle Genetics generates $110M through ADC technology license agreements

Seattle Genetics, Inc. announced today that it has achieved a milestone under its antibody-drug conjugate (ADC) collaboration with Genentech, Inc., a wholly owned member of the Roche Group.

3 Mar 2010

Blood glucose-lowering hormone FGF21 also activates brown adipose tissue metabolism

The blood glucose-lowering hormone FGF21 is also an activator of brown adipose tissue metabolism, according to the study featured on the cover of Cell Metabolism and directed by the lecturer Francesc Villarroya of the UB's Department of Biochemistry and Molecular Biology (Faculty of Biology), the Institute of Biomedicine, and the Biomedical Research Networking Centre in Physiopathology of Obesity and Nutrition.

3 Mar 2010

VUCCC files for patent protection: New treatment regimen for Type 1 insulin-dependent diabetes

VUCCC P/L is pleased to announce that it has filed for patent protection of its ground breaking new treatment regimen for Type 1 'insulin-dependent' diabetes, through the European Patent Office.

3 Mar 2010

Major sports arenas in Europe have no adequate equipment, procedures to save spectators who suffer heart attacks

Too many major sports arenas in Europe do not have adequate equipment and procedures in place to save the lives of spectators who suffer heart attacks while watching a sporting event, according to new research published online today (Wednesday 3 March) in the European Heart Journal.

3 Mar 2010

CBT effective in treating patients suffering from lupus and high levels of daily stress

This study shows that cognitive behavioural therapy (CBT) is effective in dealing with patients suffering from lupus and high levels of daily stress as it significantly reduces the incidence of psychological disorders associated with lupus and improves and maintains patients' QOL, despite there being no significant reduction in the disease activity index.

3 Mar 2010

Positive clinical trial results of EndoBarrier Gastrointestinal Liner device announced

GI Dynamics, a leader in non-surgical, endoscopic treatments for type 2 diabetes and obesity, today announced initial, positive results from a clinical trial evaluating 12 months of treatment with the EndoBarrier™ Gastrointestinal Liner.

3 Mar 2010

Report provides comprehensive insight into how physicians classify and treat patients with gout

BioTrends Research Group, Inc. is pleased to announce the availability of its TreatmentTrends®: Gout and Hyperuricemia publication. The report is based on responses to online surveys completed by 120 Rheumatologists and 57 Primary Care Physicians in the US who are managing a high number of patients with gout.

3 Mar 2010

FDA's recommendations over LABAs: AANMA advises patients to make informed decisions

Allergy & Asthma Network Mothers of Asthmatics (AANMA) encourages patients to make informed decisions about recent U.S. Food and Drug Administration (FDA) recommendations affecting patients using asthma medications known as long-acting beta agonists (LABAs) or 12-hour bronchodilators: Advair, Foradil, Serevent and Symbicort.

3 Mar 2010

New QUANTEC guidelines for safe treatment of cancer with radiation therapy

The culmination of a two-year effort to review available studies and establish new guidelines for the safe treatment of cancer with radiation therapy was published today in the International Journal of Radiation Oncology, Biology and Physics.

3 Mar 2010

Step-up treatments may benefit children with asthma on low-dose inhaled corticosteroids

Children with asthma who continue to have symptoms while using low-dose inhaled corticosteroids could benefit from increasing the dosage or adding one of two asthma drugs, a new study by researchers at Washington University School of Medicine and other institutions finds.

3 Mar 2010

Merck’s MF/F Phase III study data presented at AAAAI annual meeting

Data from two Phase III studies of Merck’s investigational fixed-dose combinations of mometasone furoate and formoterol fumarate (MF/F) were presented by researchers today in two poster presentations at the American Academy of Allergy, Asthma & Immunology (AAAAI) annual meeting.

3 Mar 2010

Diabetics at risk: Nova Scotia limits pharmacare coverage of blood glucose test strips

The Nova Scotia government's decision to limit Pharmacare coverage of blood glucose test strips for some diabetes patients places a significant financial and health burden on these Nova Scotians and violates the fundamental principle that patients and their healthcare professionals should be able to determine how to manage treatment.

3 Mar 2010

RMR can non-invasively, quickly and accurately detect presence of sCAD

Newly published data shows using a Respiratory Modulation Response (RMR) is a novel, non-invasive measure to quickly and accurately detect the presence of significant coronary artery disease (sCAD). Patients in the study with sCAD had a lower RMR compared to patients without, regardless of their risk factors or clinical history of angina, previous myocardial infarction (MI), or angioplasty.

3 Mar 2010

Study: Offspring of two parents with schizophrenia more likely to develop same illness

Offspring of two parents with schizophrenia or bipolar disorder appear more likely to develop the same illness or another psychiatric condition than those with only one parent with psychiatric illness, according to a report in the March issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

3 Mar 2010

Medical Condition News

Actemra: 38% of rheumatologists have commenced treatment

Pfizer, Medivation announce results of two dimebon Phase 3 trials in AD patients

Spectral Diagnostics receives FDA IDE approval for Toraymyxin

Gene 'addiction' of leukaemia cells

Pennsylvania makes available $400,000 in federal fund to support individuals within criminal justice system

Allergan celebrates 20th anniversary of BOTOX in Canada

Seattle Genetics generates $110M through ADC technology license agreements

Blood glucose-lowering hormone FGF21 also activates brown adipose tissue metabolism

VUCCC files for patent protection: New treatment regimen for Type 1 insulin-dependent diabetes

Major sports arenas in Europe have no adequate equipment, procedures to save spectators who suffer heart attacks

CBT effective in treating patients suffering from lupus and high levels of daily stress

Positive clinical trial results of EndoBarrier Gastrointestinal Liner device announced

Report provides comprehensive insight into how physicians classify and treat patients with gout

FDA's recommendations over LABAs: AANMA advises patients to make informed decisions

New QUANTEC guidelines for safe treatment of cancer with radiation therapy

Step-up treatments may benefit children with asthma on low-dose inhaled corticosteroids

Merck’s MF/F Phase III study data presented at AAAAI annual meeting

Diabetics at risk: Nova Scotia limits pharmacare coverage of blood glucose test strips

RMR can non-invasively, quickly and accurately detect presence of sCAD

Study: Offspring of two parents with schizophrenia more likely to develop same illness

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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