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Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

A blood test used to determine the level of inflammation in the body may offer some help in assessing colon cancer risk, according to results of a study to be presented by Vanderbilt-Ingram Cancer Center's Gong Yang, M.D., MPH, at the 101st Annual Meeting of the American Association for Cancer Research.

20 Apr 2010

RANKL inhibition may prove effective in treatment of human malignancy, suggests study

Amgen today announced results of a preclinical study demonstrating a positive response to administration of RANK-Fc against mammary tumor formation in mouse models. OPG-Fc and RANK-Fc bind to and block the action of RANKL. These molecules have a comparable mechanism of action to denosumab. The study was presented today in a late-breaking abstract at the American Association for Cancer Research (AACR) 101st Annual Meeting 2010 in Washington, D.C.

20 Apr 2010

Researchers find no correlation between AED drug load and number of adverse effects in epileptic patients

Researchers have found that polytherapy with multiple anti-epileptic drugs did not result in greater adverse effects than monotherapy for patients with refractory epilepsy. This observational study also found AED load was not a factor in causing adverse effects, but suggests that individual susceptibility, type of AEDs used, and physicians' skills determine which patients suffer adverse effects.

20 Apr 2010

Researchers evaluate probiotics' curative effects for treating ulcerative colitis

Inflammatory bowel disease is a chronic recurrent disease, which mainly consists of ulcerative colitis and Crohn's disease, and whose causes are as yet unclear. Many clinical and research studies have indicated that intestinal flora dysbacteriosis contributes to the pathogenesis of ulcerative colitis. Probiotics are non-pathogenic beneficial flora, which have important effects on maintaining the balance of intestinal flora.

20 Apr 2010

Severe and necrotizing AP characterized by depletion of circulating lymphocytes

Mortality of patients with severe acute pancreatitis (SAP) approaches 30%-40%. An imbalance between the early systemic inflammatory response syndrome (SIRS), and the later compensatory counter-inflammatory response, and development of multiple organ failure (MOF) are considered to be the primary causes of morbidity and mortality in SAP. Excessive leukocyte activation (including neutrophils and monocyte-macrophage lineage) with cytokinemia play a critical role in the pathogenesis of pancreatitis and even more so, of the subsequent inflammatory response.

20 Apr 2010

Certain genetic mutations lead to Type 1 diabetes: The Scripps Research Institute

Scientists from The Scripps Research Institute have provided an answer to the 40-year-old mystery of how certain genetic mutations lead to Type 1 diabetes. This new molecular understanding could lead to novel therapies for Type 1 diabetes and other autoimmune diseases.

20 Apr 2010

Gamma-prime fibrinogen test can help better predict people at risk for heart attack

A simple blood test can identify people who are at risk for a heart attack, including thousands who don't have high cholesterol, according to researchers at Oregon Health & Science University.

20 Apr 2010

Basal ganglia and cerebellum linked together to form integrated functional network: Researchers

Researchers at the University of Pittsburgh have found new evidence that the basal ganglia and the cerebellum, two important areas in the central nervous system, are linked together to form an integrated functional network. The findings are available online this week in the Proceedings of the National Academy of Sciences.

20 Apr 2010

AstraZeneca/Targacept's TC-5214 for treatment resistant depression to earn Decision Resources' gold standard status

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, for treatment resistant depression therapy, AstraZeneca/Targacept's TC-5214 will earn Decision Resources' proprietary clinical gold standard status in 2013 (following its approval that year) and through 2018.

20 Apr 2010

Screening rates for skin cancer low among middle-aged and older Caucasian adults: CINJ study

Among people over 50, those who did not finish high school or have not recently had common cancer screenings such as a mammogram, prostate-specific antigen test or colorectal cancer screening, are also less likely to be screened for skin cancer.

20 Apr 2010

EHSI incorporates outpatient treatment options into MedAnywhere HHC Module

Emerging Healthcare Solutions, Inc. revealed today that they are working to incorporate outpatient treatment options into the new MedAnywhere medical iPhone app and that the first module to be added to development will be for cost saving Hemochromatosis management.

20 Apr 2010

Study underscores potential for VBL Therapeutics VB-111 as broad-spectrum cancer therapy

VBL Therapeutics today announced positive results from preclinical and Phase 1 studies evaluating the company's lead anti-cancer agent, VB-111 - a first-in-class, targeted biological agent shown to work via dual-action, anti-angiogenic and vascular disruptive mechanism of action - in metastatic cancer. Preclinical data evaluating VB-111 in a comprehensive set of in vivo studies employing the Lewis Lung metastasis mouse model showed the compound to be safe and specific, with a 90% reduction in tumor burden of lung metastases after only one injection.

20 Apr 2010

S1P5 may serve as future strategy in biotherapy for esophageal cancer: Study

Esophageal cancer is one of the most common malignancies worldwide. Its mortality is very high due to relatively late diagnosis and inefficient treatment. The ability to reverse the outcome of esophageal cancer is limited due to a poor understanding of its biology. Progression of esophageal cancer may be associated with sphingosine 1-phosphate and its receptors S1P1-5, which play an important role in other cancers.

20 Apr 2010

Meat cooked at high temperatures increases risk of developing bladder cancer

People who eat meat frequently, especially meat that is well done or cooked at high temperatures, may have a higher chance of developing bladder cancer, according to a large study at The University of Texas M. D. Anderson Cancer Center presented at the American Association for Cancer Research 101st Annual Meeting 2010. This risk appears to increase in people with certain genetic variants.

20 Apr 2010

Block by Block campaign to educate community, reduce impact of diabetes

It started with a simple medical survey in the Humboldt Park neighborhood on Chicago's near Northwest side whose results were reported in the Journal of Epidemiology in 2006.

20 Apr 2010

$Innovative new contact lens to correct hyperopia without refractive surgery$

Innovative new contact lens to correct hyperopia without refractive surgery

Jaume Pauné, a graduate of the Master's Degree in Optometry and Vision Sciences at the UPC-Barcelona Tech's College of Optics and Optometry, has designed an innovative new contact lens that will improve the vision quality of thousands of people without surgery. The Spanish Association of Opticians and Optometrists has granted its National Award to Mr. Pauné for his innovative work in this field.

20 Apr 2010

CryoSTAT cold therapy for hemorrhoids

Revolutionary new CryoSTAT is here to put the fire out when it comes to hemorrhoids by treating them on contact with cold therapy which has a proven track record of providing instant relief with no mess.

20 Apr 2010

New technique that involves voice analysis to diagnose Parkinson's disease developed

A new technique assisting in early diagnosis of Parkinson's disease has been developed by Prof. Shimon Sapir of the Department of Communication Sciences and Disorders at the University of Haifa. This technique involves analysis of voice and articulation. The research was carried out alongside U.S. scientists and with funding from the National Institutes of Health, and results have been published in the Journal of Speech, Language, and Hearing Research.

20 Apr 2010

Low-dose aspirin associated with increased risk of gastrointestinal bleeding

Low-dose aspirin (LDA) is one of the main agents used for the prevention of thromboembolic vascular events, and has the advantages of both low cost and a prolonged duration of antiplatelet action; however, it is associated with a doubling of the risk of gastrointestinal bleeding, even at doses as low as 75 mg daily. The gender differences in the clinical manifestations of LDA-associated gastroduodenal mucosal injury have not been well studied.

20 Apr 2010

Hematological malignancies conference to provide update on blood-borne cancer

John Theurer Cancer Center at Hackensack University Medical Center will host a hematological malignancies conference for physicians and patients on Friday, April 23 and Saturday, April 24. The event, entitled "Current and Innovative Modalities in the Management of Hematological Malignancies", is part of John Theurer Cancer Center's commitment to provide both healthcare professionals as well as patients with an update on the newest advances in the field of blood-borne cancers.

20 Apr 2010

Medical Condition News

Blood test to determine inflammation levels in body may help assess colon cancer risk: Study

RANKL inhibition may prove effective in treatment of human malignancy, suggests study

Researchers find no correlation between AED drug load and number of adverse effects in epileptic patients

Researchers evaluate probiotics' curative effects for treating ulcerative colitis

Severe and necrotizing AP characterized by depletion of circulating lymphocytes

Certain genetic mutations lead to Type 1 diabetes: The Scripps Research Institute

Gamma-prime fibrinogen test can help better predict people at risk for heart attack

Basal ganglia and cerebellum linked together to form integrated functional network: Researchers

AstraZeneca/Targacept's TC-5214 for treatment resistant depression to earn Decision Resources' gold standard status

Screening rates for skin cancer low among middle-aged and older Caucasian adults: CINJ study

EHSI incorporates outpatient treatment options into MedAnywhere HHC Module

Study underscores potential for VBL Therapeutics VB-111 as broad-spectrum cancer therapy

S1P5 may serve as future strategy in biotherapy for esophageal cancer: Study

Meat cooked at high temperatures increases risk of developing bladder cancer

Block by Block campaign to educate community, reduce impact of diabetes

Innovative new contact lens to correct hyperopia without refractive surgery

CryoSTAT cold therapy for hemorrhoids

New technique that involves voice analysis to diagnose Parkinson's disease developed

Low-dose aspirin associated with increased risk of gastrointestinal bleeding

Hematological malignancies conference to provide update on blood-borne cancer

Freezing Point Osmometry in Life Science Applications

Precision in every drop: Inside Hamilton’s syringe technology

Exploring the Future of Neuroscience Drug Discovery

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