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When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate.

16 Feb 2010

Octapharma initiates Phase III studies for new, high purity IVIG in treatment of primary immune deficiency

Octapharma AG today announced the start of the first of a series of Phase III studies for its new 10% high purity intravenous immunoglobulin (IVIG). The study will investigate the efficacy and safety of this novel immunoglobulin in the treatment of primary immune deficiency and, together with results from additional upcoming studies, will support its regulatory filing in Europe and the US.

16 Feb 2010

Case study demonstrates positive impact of diabetes management program

A case study published in the current issue of the American Journal of Health-System Pharmacists, demonstrates the positive impact of a diabetes management program designed to educate and motivate members to engage in their health care. The program was implemented by CVS Caremark and Polk County, Florida, a self-insured government employer client.

16 Feb 2010

Simple, inexpensive test to help determine concussion in athletes

A simple test of reaction time may help determine whether athletes have sustained a concussion (also known as mild traumatic brain injury) and when they are ready to play again, according to a study released today that will be presented at the American Academy of Neurology's 62nd Annual Meeting in Toronto April 10 to April 17, 2010.

16 Feb 2010

Revisional bariatric surgery linked to higher risk of complications

Revisional bariatric surgery appears to be associated with a higher risk of complications than the initial procedure, according to a report in the February issue of Archives of Surgery, one of the JAMA/Archives journals.

16 Feb 2010

Researchers find new risk factor for early-onset dementia

Examining brain tissue from over 500 individuals in 11 countries, researchers from the University of Pennsylvania School of Medicine and the Children's Hospital of Philadelphia, and colleagues found a new risk factor for the second-most-common cause of early-onset dementia after Alzheimer's disease.

16 Feb 2010

Scientists discover molecular pathway to regenerate damaged kidney tissues

Scientists have discovered a molecular pathway that works through the immune system to regenerate damaged kidney tissues and may lead to new therapies for repairing injury in a number of organs.

16 Feb 2010

AstraZeneca, Rigel Pharmaceuticals announce exclusive worldwide license agreement for R788

AstraZeneca and Rigel Pharmaceuticals today announced an exclusive worldwide license agreement for the global development and commercialization of fostamatinib disodium (R788), Rigel's late-stage investigational product for rheumatoid arthritis (RA) and additional indications.

16 Feb 2010

Use of non-steroidal anti-inflammatory drugs not associated with risk of squamous cell skin cancer

Contrary to previous hypotheses, the use of non-steroidal anti-inflammatory drugs does not appear associated with risk of squamous cell skin cancer, according to a report posted online today that will appear in the April print issue of Archives of Dermatology, one of the JAMA/Archives journals.

16 Feb 2010

Clive Svendsen to receive American Academy of Neurology Sheila Essey Award for his research on ALS

Clive Svendsen, Ph.D., director of the Cedars-Sinai Regenerative Medicine Institute, is receiving the American Academy of Neurology Sheila Essey Award for his research on ALS (amyothrophic lateral sclerosis).

16 Feb 2010

CNRS-Institut researchers identify 'virulence factor' that inhibits host immune response

Oncogenic retroviruses are a particular family of viruses that can cause some types of cancer. Thierry Heidmann and his colleagues in the CNRS-Institut Gustave Roussy-Université Paris Sud 11 "Rétrovirus endogènes et éléments rétroïdes des eucaryotes supérieurs" Laboratory have studied these viruses. They have identified a "virulence factor" that inhibits the host immune response and allows the virus to spread throughout the body.

16 Feb 2010

Children's Hospital of Philadelphia awarded two grants to research into cellular therapies for blood disorders

The new decade may herald an era of cell therapy -- treating human diseases by delivering highly specific beneficial cells. In the wake of an NIH decision late last year permitting federally funded researchers to use new lines of human embryonic stem cells, the door has opened more widely to stem cell research.

16 Feb 2010

Tinnitus not a highly inherited condition, says study

Tinnitus, or ringing in the ears, does not appear to be a highly inherited condition (i.e., does not pass frequently from parents to offspring), according to a report in the February issue of Archives of Otolaryngology-Head & Neck Surgery, one of the JAMA/Archives journals.

16 Feb 2010

Research findings highlight the vital need for better secondary stroke prevention

New research finds that one out of 12 people who have a stroke will likely soon have another stroke, and one out of four will likely die within one year. Researchers say the findings highlight the vital need for better secondary stroke prevention. The study is published in the February 16, 2010, issue of Neurology-, the medical journal of the American Academy of Neurology.

16 Feb 2010

Progressive walking reduces arthritic pain, improves physical function

"Progressive walking" combined with glucosamine sulphate supplementation has been shown to improve the symptoms of osteoarthritis. Researchers writing in BioMed Central's open-access journal Arthritis Research and Therapy found that patients who walked at least two bouts of 1500 steps each on three days of the week reported significantly less arthritis pain, and significantly improved physical function.

16 Feb 2010

Genous Bio-engineered R stent beneficial for patients not suitable for long term DAPT

OrbusNeich announced that clinical data presented at the Joint Intervention Meeting (JIM) 2010 in Rome provide further evidence that the company's Genous stent could be a treatment of choice for patients not suitable for long term dual antiplatelet therapy. The investigator initiated, 50 patient, multicenter study evaluated the safety of patients receiving only 10 days dual antiplatelet therapy undergoing stenting with the Genous Bio-engineered R stent. The primary endpoint was the absence of stent thrombosis or any occlusion within three months.

15 Feb 2010

Botulinum injection used for cosmetic purposes may reduce migraine headaches

A preliminary study suggests the same type of botulinum injection used for cosmetic purposes may be associated with reduced frequency of migraine headaches that are described as crushing, vicelike or eye-popping (ocular), but not pain that is experienced as a buildup of pressure inside the head, according to a report in the February issue of Archives of Dermatology, one of the JAMA/Archives journals.

15 Feb 2010

Stem cells intentionally cut and then repair their own DNA to develop new tissues

A new study from the Ottawa Hospital Research Institute (OHRI) and the University of Ottawa suggests that stem cells intentionally break their own DNA as a way of regulating tissue development. The study, published in Proceedings of the National Academy of Science (PNAS), could dramatically change how researchers think about tissue development, stem cells and cancer.

15 Feb 2010

CEO Roundtable on Cancer salutes Duke Blue Devils basketball team coach on 1000th game

The CEO Roundtable on Cancer salutes Mike Krzyzewski, who on Saturday, February 13th will celebrate his 1000th game leading the Duke Blue Devils men’s basketball team. Tomorrow afternoon’s game at 1 pm against the University of Maryland will mark an amazing achievement only seven other coaches in the history of the game have done at a single school. Beginning in 1980, Coach K’s career at Duke has been nothing short of incredible, including leading the school to 294 wins from 2000-09 – the most in the history of the game by any school in any decade.

15 Feb 2010

Structure of 'DNA repair engine' that reverses beneficial effects of chemotherapy deciphered

Cancer Research UK scientists have deciphered the first structure of 'a DNA repair engine' that reverses the beneficial effects of chemotherapy, according to research published in Nature Structural and Molecular Biology* today.

15 Feb 2010

Medical Condition News

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

Octapharma initiates Phase III studies for new, high purity IVIG in treatment of primary immune deficiency

Case study demonstrates positive impact of diabetes management program

Simple, inexpensive test to help determine concussion in athletes

Revisional bariatric surgery linked to higher risk of complications

Researchers find new risk factor for early-onset dementia

Scientists discover molecular pathway to regenerate damaged kidney tissues

AstraZeneca, Rigel Pharmaceuticals announce exclusive worldwide license agreement for R788

Use of non-steroidal anti-inflammatory drugs not associated with risk of squamous cell skin cancer

Clive Svendsen to receive American Academy of Neurology Sheila Essey Award for his research on ALS

CNRS-Institut researchers identify 'virulence factor' that inhibits host immune response

Children's Hospital of Philadelphia awarded two grants to research into cellular therapies for blood disorders

Tinnitus not a highly inherited condition, says study

Research findings highlight the vital need for better secondary stroke prevention

Progressive walking reduces arthritic pain, improves physical function

Genous Bio-engineered R stent beneficial for patients not suitable for long term DAPT

Botulinum injection used for cosmetic purposes may reduce migraine headaches

Stem cells intentionally cut and then repair their own DNA to develop new tissues

CEO Roundtable on Cancer salutes Duke Blue Devils basketball team coach on 1000th game

Structure of 'DNA repair engine' that reverses beneficial effects of chemotherapy deciphered

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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