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Brain mechanisms behind compulsive behaviors in Parkinson's disease patients

New research unravels the brain mechanisms that underlie the ability of a standard drug treatment for Parkinson's to elicit compulsive behaviors in some patients with the disease. The study, published by Cell Press in the January 14th issue of the journal Neuron, provides fascinating new insight into the brain mechanisms that underlie a predisposition to behavioral addictions, such as pathological gambling and shopping.

18 Jan 2010

Dopamine replacement therapy causes brain dysfunction in patients with Parkinson disease, study says

People with Parkinson's Disease are more likely to display abnormal social behaviour and make poor decisions in ambiguous circumstances if they are pathological gamblers, according to research in the January issue of the European Journal of Neurology.

18 Jan 2010

Prescription drugs prove effective in managing moderate to severe psoriasis

Clinical trials to test the effectiveness of two prescription drugs for the debilitating skin condition psoriasis have revealed significant differences that should help inform physicians treating patients with the condition.

18 Jan 2010

New insights into molecular interaction between probiotics and altered host intestinal ecosystem in IPAA

Total proctocolectomy with ileal J-pouch-anal anastomosis (IPAA) is the surgical treatment of choice for patients with refractory ulcerative colitis (UC). Although the surgery generally cures UC allowing a significant improvement of health-related quality of life, complications can occur after IPAA.

18 Jan 2010

Medical professionals and breast cancer survivors to attend 10th international conference in Georgia

2010 marks the 10th anniversary of the only international conference dedicated to the critical issues of young breast cancer survivors and those who care about them.

18 Jan 2010

Surveillance colonoscopy need to be better aligned with patients' risks for colorectal cancer

How often patients receive surveillance colonoscopy may need to be better aligned with their risks for colorectal cancer, according to two papers published this month by University of Pittsburgh School of Medicine researchers.

18 Jan 2010

New genetic risk factor for Parkinson's disease identified

An international team of doctors and human geneticists has identified a new genetic risk factor for Parkinson's disease. The institutions involved in the study were the Institute of Human Genetics of Helmholtz Zentrum München and Technische Universität München, the Neurological Clinic of Ludwig-Maximilians-Universität Munich (LMU) and the Mitochondrial Research Group of Newcastle University, Newcastle upon Tyne, UK.

18 Jan 2010

High BMI among children and adolescents continues to be a public health concern in the U.S.

The prevalence of high weight for length or high body mass index (BMI) among children and teens in the U.S. (i.e., at or above the 95th percentile), ranges from approximately 10 percent for infants and toddlers, to approximately 18 percent for adolescents and teenagers, although these rates appear to have remained relatively stable over the past 10 years, except for an increase for 6- to 19-year-old boys who are at the very heaviest weight levels, according to a study appearing in the January 20 issue of JAMA. The study is being published early online because of its public health importance.

18 Jan 2010

Molecules capable of reversing brain abnormalities in PD identified

Scientists identified several molecules capable of reversing the brain abnormalities of Parkinson's disease (PD), while also uncovering new clues for its origin in a study just published in the journal Disease Models and Mechanisms. PD is characterised by abnormal deposits of a brain protein called alpha-synuclein throughout the damaged brain regions, but exactly what they do there is not clear. The fact that their numbers and spreading are associated disease progression has made them, however, a major point of interest in PD research.

18 Jan 2010

Table saw-related injuries remain high; new technology to prevent injuries needs to be affordable

Woodworking is a popular hobby, with table saws being owned and used by an estimated 6 million to 10 million people in the United States. Although table saws are associated with more injuries than any other woodworking tool, there have been no previously published national studies of table saw-related injuries.

18 Jan 2010

New report providing insight for companies developing therapies to treat hematologic malignancies published

MedPredict Market Research, a global provider of pharmaceutical competitive intelligence and market research, has published a new report providing critical strategic insight for companies developing therapies to treat hematologic malignancies.

18 Jan 2010

Study indicates young Swedish men consume excess amount of salt

Young Swedish men are consuming at least double the recommended amount of salt according to a study carried out by the Sahlgrenska Academy at the University of Gothenburg and Sahlgrenska University Hospital.

18 Jan 2010

Study shows key differences among Hispanic populations on the risk of cardiovascular disease

Latinos are not all the same when it comes to risk of heart disease, and a new study by a Columbia University researcher shows key differences among Hispanic populations that doctors should take into account in trying to stem the risk of cardiovascular disease in this large and growing subset of the U.S. population.

18 Jan 2010

Cancer Research UK welcomes government's decision to ban sunbeds

Cancer Research UK welcomes the government's intention to ban the use of sunbeds by under-18s following the launch of a Private Member's Bill in Parliament by Julie Morgan, MP for Cardiff North.

18 Jan 2010

New neuroprotective drug trial for people with traumatic brain injuries

A clinical trial of a new neuroprotective drug for people with traumatic brain injuries will be offered to patients seen in UC Davis Medical Center's level-1 trauma center, through an $8 million grant funded by the Congressionally Directed Medical Research Program of the U.S. Department of Defense.

18 Jan 2010

Down syndrome and Alzheimer's disease are the same

Nearly 20 years ago Huntington Potter kicked up a storm of controversy with the idea that Down syndrome and Alzheimer's were the same disease. Now the evidence is in: He was right.

18 Jan 2010

New discovery likely to have significant influence on cell replacement therapies

MIT neuroscientists have discovered that when it comes to new neurons in the adult brain, the squeakiest wheels get the grease.

18 Jan 2010

Treatment for metastatic tumor based on its unique protein makeup

Imagine if treatments for disease could be based not on a patient's diagnosis but instead on the characteristics of their tissue. By identifying and decoding the cryptic messages hidden deep inside the human proteome, scientists and physicians who study personalized medicine are seeking more effective treatments and disease management for patients.

18 Jan 2010

Stress induces signals that cause cells to develop into tumors

Stress induces signals that cause cells to develop into tumors, Yale researchers have discovered. The research, published online Jan. 13 in the journal Nature, describes a novel way cancer takes hold in the body and suggests new ways to attack the deadly disease.

18 Jan 2010

Novel technique eliminates radiation exposure to patients and medical providers

A growing body of research continues to warn of the potential long-term effects of radiation exposure for patients and medical providers during such imaging procedures as x-rays and computed tomography (CT) scans, both of which are traditionally used with certain heart procedures.

18 Jan 2010

Medical Condition News

Brain mechanisms behind compulsive behaviors in Parkinson's disease patients

Dopamine replacement therapy causes brain dysfunction in patients with Parkinson disease, study says

Prescription drugs prove effective in managing moderate to severe psoriasis

New insights into molecular interaction between probiotics and altered host intestinal ecosystem in IPAA

Medical professionals and breast cancer survivors to attend 10th international conference in Georgia

Surveillance colonoscopy need to be better aligned with patients' risks for colorectal cancer

New genetic risk factor for Parkinson's disease identified

High BMI among children and adolescents continues to be a public health concern in the U.S.

Molecules capable of reversing brain abnormalities in PD identified

Table saw-related injuries remain high; new technology to prevent injuries needs to be affordable

New report providing insight for companies developing therapies to treat hematologic malignancies published

Study indicates young Swedish men consume excess amount of salt

Study shows key differences among Hispanic populations on the risk of cardiovascular disease

Cancer Research UK welcomes government's decision to ban sunbeds

New neuroprotective drug trial for people with traumatic brain injuries

Down syndrome and Alzheimer's disease are the same

New discovery likely to have significant influence on cell replacement therapies

Treatment for metastatic tumor based on its unique protein makeup

Stress induces signals that cause cells to develop into tumors

Novel technique eliminates radiation exposure to patients and medical providers

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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