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Oral cladribine to be the first oral disease-modifying multiple sclerosis therapy despite receiving RTF letter

Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that a recent "refuse to file" (RTF) letter issued by the Food and Drug Administration (FDA) regarding Merck Serono's oral cladribine has heightened the competition between oral cladribine and its primary competitor, Novartis/Mitsubishi Tanabe's FTY-720 (fingolimod), to be the first oral disease-modifying multiple sclerosis therapy to reach the market in the United States.

6 Jan 2010

Similar effectiveness in treatment options for low-risk prostate cancer; research may help improve patient outcomes

A comprehensive appraisal of the management and treatment options for low-risk prostate cancer found that the rates of survival and tumor recurrence are similar among the most common treatment approaches, although costs can vary considerably.

6 Jan 2010

Toxic chemicals make us susceptible to a wide range of diseases

From the Industrial Revolution and onward, the world has become an environment that is overflowing with dangerous toxins. Mass manufacturing has resulted in thousands of chemical pollutants being released in the atmosphere, water, and soil. As well, there has been a widespread increase of chemicals being added to almost every type of food and retail product.

6 Jan 2010

International Headache Society publishes new guidelines to stimulate more research on headache treatment

If you're one of the millions of headache sufferers around the world, more effective relief might be on the way in years to come. That's because the International Headache Society has just published new research guidelines intended to stimulate more research into headache treatment, and to provide researchers with guidelines to cut health risks associated with treatment.

6 Jan 2010

Renowned ophthalmologist performs innovative procedure on patient suffering from severe visual impairment

Ten years ago, Southern Californian resident Kenny Atkins suffered from severe visual impairment caused by coning of the cornea, otherwise known as keratoconus. Prescription glasses and contact lenses proved to be ineffective, and Atkins needed a solution fast – as an ocean lifeguard, Atkins’ ability to see could mean the difference between life and death.

6 Jan 2010

Findings open up significant possibilities for developing micro-screening devices for drug discovery

A Nobel-winning process for testing new drugs to treat diseases such as Huntington's, Parkinson's, and muscular dystrophy is getting an electrical charge.

6 Jan 2010

Montefiore Medical Center first to perform minimally invasive procedure on uterine fibroids

Montefiore Medical Center recently became the only hospital on the East Coast to conduct the Radio Frequency Ablation procedure to shrink uterine fibroids in women 30 years and older.

6 Jan 2010

Excessive gestational weight gain in obese women is associated with severe medical conditions

Recent recommendations by the Institute of Medicine (IOM) call for women who are overweight or obese to gain more weight than they should, a Saint Louis University obstetrician wrote in a January commentary for Obstetrics & Gynecology.

6 Jan 2010

Data from national surveys shows few Americans receive consistent treatment for MDD

Only about half of Americans diagnosed with major depression in a given year receive treatment for it and even fewer - about one-fifth - receive treatment consistent with current practice guidelines, according to data from national surveys supported by the National Institute of Mental Health of the National Institutes of Health.

6 Jan 2010

Study finds self-management alone may effectively treat knee osteoarthritis

Researchers participating in the Multidimensional Intervention for Early Osteoarthritis of the Knee (Knee Study) determined that physically inactive, middle-aged people with symptomatic osteoarthritis benefitted equally from strength training regimens, self-management programs, or a combination of the two. Details of this study are available in the January 2010 issue of Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology.

6 Jan 2010

Study shows prevalence of SED remains high after Hurricane Katrina

A team made up of mental health professionals, emergency response experts, and researchers from several universities, including Virginia Tech, has published the results of a study that shows serious emotional disturbances among children who were affected by Hurricane Katrina.

6 Jan 2010

Untreated hearing loss can put personal safety and overall health at risk

With hearing loss in America approaching what medical researchers say may be epidemic proportions, a top hearing care executive is calling for this to be the year that hearing care is recognized as a medical necessity.

6 Jan 2010

More research needed to assess psychological debriefing in schools

There is no evidence to support psychological debriefing in schools after traumatic events such as violence, suicides and accidental death, which runs counter to current practice in some Canadian school jurisdictions, according to a commentary http://www.cmaj.ca/embargo/cmaj091621.pdf in CMAJ (Canadian Medical Association Journal) www.cmaj.ca .

6 Jan 2010

Lockton Insurance Brokers raises funds to help people with ALS

Los Angeles Dodgers pitcher Randy Wolf and PGA tour player Jason Gore along with 84 players recently gathered for a day of golf at the Valencia Country Club, raising awareness and funds for people with ALS (amyotrophic lateral sclerosis), commonly referred to as Lou Gehrig 's disease.

6 Jan 2010

New survival prediction equation may impact clinical trials for treating PAH

Setting out to determine the survival of patients with pulmonary arterial hypertension (PAH), researchers at the University of Chicago Medical Center and their colleagues also discovered that an equation used for more than 20 years to predict survival is outdated.

6 Jan 2010

Patient enrolled in Phase I clinical study of two investigational compounds: MK-2206 and AZD6244

Dr. Anthony Tolcher, clinical director for South Texas Accelerated Research Therapeutics (START) at the START Center for Cancer Care in San Antonio, announced today that the first patient has been enrolled in a groundbreaking Phase I clinical trial of a novel combination anticancer regimen composed of two investigational compounds: MK-2206 from Merck & Co., Inc. and AZD6244 (ARRY-886*) from AstraZeneca.

6 Jan 2010

Sleep deficits in high school students may lead to depression, headache and poor performance

Only about 8 percent of high school students get enough sleep on an average school night, a large new study finds. The others are living with borderline-to-serious sleep deficits that could lead to daytime drowsiness, depression, headaches and poor performance at school.

6 Jan 2010

Innexus Biotechnology designs new psoriasis product

InNexus Biotechnology Inc. (TSX.V: IXS) (www.ixsbio.com), a drug development company commercializing the next generation of antibodies based on its groundbreaking Dynamic Cross Linking (DXL™) technology, today announced the development of a new psoriasis product based on its proprietary dermal permeating Transmab™ technology.

6 Jan 2010

Life-saving therapeutic interventions possible with early detection of hepatitis C recurrence

A recent study by doctors from the Hospital Cl-nic in Barcelona, Spain determined that repeated liver stiffness measurements (LSM) in the first year following liver transplant (LT) could discriminate between slow and rapid "fibrosers" (patients with fibrosis stage of F2-F4 one year post LT).

6 Jan 2010

Keryx Biopharmaceuticals reaches SPA agreement for Phase 3 clinical program for Zerenex

Keryx Biopharmaceuticals, Inc. announced today that it has reached agreement with the U.S. Food and Drug Administration (FDA) regarding a Special Protocol Assessment (SPA) on the design of a Phase 3 clinical program for Zerenex(TM) (ferric citrate), its iron-based phosphate binder for the treatment of elevated serum phosphorous levels, or hyperphosphatemia, in patients with end-stage renal disease (ESRD).

6 Jan 2010

Medical Condition News

Oral cladribine to be the first oral disease-modifying multiple sclerosis therapy despite receiving RTF letter

Similar effectiveness in treatment options for low-risk prostate cancer; research may help improve patient outcomes

Toxic chemicals make us susceptible to a wide range of diseases

International Headache Society publishes new guidelines to stimulate more research on headache treatment

Renowned ophthalmologist performs innovative procedure on patient suffering from severe visual impairment

Findings open up significant possibilities for developing micro-screening devices for drug discovery

Montefiore Medical Center first to perform minimally invasive procedure on uterine fibroids

Excessive gestational weight gain in obese women is associated with severe medical conditions

Data from national surveys shows few Americans receive consistent treatment for MDD

Study finds self-management alone may effectively treat knee osteoarthritis

Study shows prevalence of SED remains high after Hurricane Katrina

Untreated hearing loss can put personal safety and overall health at risk

More research needed to assess psychological debriefing in schools

Lockton Insurance Brokers raises funds to help people with ALS

New survival prediction equation may impact clinical trials for treating PAH

Patient enrolled in Phase I clinical study of two investigational compounds: MK-2206 and AZD6244

Sleep deficits in high school students may lead to depression, headache and poor performance

Innexus Biotechnology designs new psoriasis product

Life-saving therapeutic interventions possible with early detection of hepatitis C recurrence

Keryx Biopharmaceuticals reaches SPA agreement for Phase 3 clinical program for Zerenex

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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