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EC grants orphan drug designation for MP4CO for treating sickle cell disease

Sangart, Inc., a global biopharmaceutical company dedicated to developing life-saving medicines specifically designed to enhance the perfusion and oxygenation of ischemic (oxygen deprived) tissues through targeted oxygen and other gas delivery, today announced that the European Commission (EC) has granted orphan medicinal product designation for MP4CO for the treatment of sickle cell disease.

10 Dec 2009

Robarts researcher identifies protein which regulates cell suicide

When cells experience DNA damage, they'll try to repair it. But if that fails, the damaged cells are supposed to self-destruct, a process called apoptosis. A cancer researcher at Robarts Research Institute at The University of Western Ontario has identified a protein that regulates apoptosis, a new discovery which has implications for both the diagnosis and treatment of cancer. Caroline Schild-Poulter's findings are now published online in the journal Molecular Cancer Research.

10 Dec 2009

Updated NCCN Guidelines include maintenance therapy for patients with metastatic disease

The National Comprehensive Cancer Network (NCCN) recently updated the NCCN Guidelines for Non-Small Cell Lung Cancer (NSCLC) to incorporate a new section about maintenance therapy, a number of new indications for specific therapies for advanced NSCLC, and the recently revised staging system for lung cancer.

10 Dec 2009

New health study reveals Ontario women less likely to receive cardiac care than men

Gender differences persist in the quality of cardiac care across Ontario, according to a health study by researchers at St. Michael's Hospital and the Institute for Clinical Evaluative Sciences (ICES).

10 Dec 2009

Researchers dispel myths on increased incidence of autism disorder

There has been a major increase in the number of children diagnosed with autistic spectrum disorders over the last two decades - the question is why? Researchers have found a sharp difference between the beliefs of ordinary people and medical experts about the reasons for the increased incidence of autism.

10 Dec 2009

UC Davis receives NFL grant to study innovative ways for knee repair

NFL Charities, the charitable foundation of the National Football League, has awarded a grant of $125,000 to UC Davis for research on new ways to repair injured knees.

10 Dec 2009

Second pivotal Phase 3 trial to evaluate investigational Lp-PLA2 inhibitor darapladib initiated

Attached is a press release issued earlier this morning by GlaxoSmithKline, announcing that GSK has initiated its second pivotal Phase 3 trial to evaluate the efficacy of long-term treatment with the investigational Lp-PLA2 inhibitor darapladib in men and women with acute coronary syndrome (ACS).

10 Dec 2009

Scientists identify potential drug development target for epilepsy seizures

A team of scientists from The University of Alabama used worms to reel in information that they hope will lead to a greater understanding of cellular mechanisms that may be exploited to treat epilepsy.

10 Dec 2009

JMC receives NIH grant to establish center of excellence for autoimmune diseases

The Department of Neurology at Jefferson Medical College (JMC) of Thomas Jefferson University has been awarded a multi-million dollar grant from the National Institutes of Health (NIH) for the creation of a center of excellence to study autoimmune diseases from basic science research to its translation into clinical applications.

10 Dec 2009

New research suggests cancer drug may also help patients suffering from asthma

Scientists at the University of Edinburgh found that the drug - R-Roscovitine - helps to kill certain immune cells which can exacerbate symptoms associated with asthma.

10 Dec 2009

New research shows increase risk of cardiovascular disease for people on low-carbohydrate high-fat diets

New scientific research has shown that low-carbohydrate high-fat diets, made popular by the likes of the Atkins diet, do not achieve more weight loss than low-fat high-carbohydrate diets. Worryingly, the research, lead by Dr Steven Hunter from the Royal Victoria Hospital, Belfast, also shows significantly increased risks of cardiovascular disease for people following low-carbohydrate high-fat diets

9 Dec 2009

Additional data from ALS patients enrolled in confirmatory Phase III STAR trial announced

AVANIR Pharmaceuticals, Inc. today announced additional data from the subset of patients with amyotrophic lateral sclerosis (ALS) enrolled in the confirmatory Phase III STAR trial.

9 Dec 2009

More number of obese adults are turning to bariatric surgery as a last resort, says WHO

The obesity epidemic is a staggering public health problem and despite increased attention and education, the WHO still predicts the number of obese adults worldwide to increase from 400 million to 700 million between 2005 and 2015.

9 Dec 2009

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

Results of a preliminary study by scientists at the National Institutes of Health and Johns Hopkins show that "mini" stem cell transplantation may safely reverse severe sickle cell disease in adults.

9 Dec 2009

MLL team finds 454 Sequencing technology promising for leukemia genetic characterization

This week at the 51st American Society for Hematology Annual Meeting, a team of researchers from the MLL Munich Leukemia Laboratory presented results from a series of groundbreaking studies which explore alternative, high-throughput 454 Sequencing methods for distinguishing and characterizing the many forms of leukemia and myeloproliferative disorders.

9 Dec 2009

RegeneRx Biopharmaceuticals completes Phase I trial evaluating systemic administration of RGN-352

REGENERX BIOPHARMACEUTICALS, INC. announced today that it has completed and analyzed the safety data from its double-blind, placebo controlled Phase I clinical trial evaluating the systemic administration of RGN-352. The trial included testing of a single escalating intravenous dose of the drug candidate on forty healthy volunteers in Phase IA and, subsequently, over a fourteen-day treatment period on forty volunteers in Phase IB.

9 Dec 2009

Decision Resources reports increased uptake of TNF-alpha inhibitors for Crohn's disease

Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that compared to last year's analysis of U.S. patient-level claims data, TNF-alpha inhibitors are being used more often to treat newly diagnosed patients suffering from Crohn's disease.

9 Dec 2009

Varian Medical Systems receives IDG's InfoWorld 100 Award for innovative use of IT

Zenprise, Inc., a provider of mobile management software, today announced its customer, Varian Medical Systems Inc., received IDG's InfoWorld 100 Award based on its deployment of the Zenprise MobileManager platform. The InfoWorld 100 Awards recognizes the top 100 most innovative uses of IT initiatives to further business goals.

9 Dec 2009

Novartis presents 6-month results from its EVEREST study for PCV

QLT Inc. welcomed the 6-month results from the Novartis-sponsored EVEREST study which were presented during a scientific review today by Novartis in Basel, Switzerland.

9 Dec 2009

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

Sangamo BioSciences, Inc. announced today the presentation of preliminary data from the Phase 2 clinical trial of its ZFP Therapeutic(TM) program to develop SB-509 as a treatment for amyotrophic lateral sclerosis (ALS) at a Work in Progress session at the 20th International Symposium on ALS/MND held in Berlin, Germany.

9 Dec 2009

Medical Condition News

EC grants orphan drug designation for MP4CO for treating sickle cell disease

Robarts researcher identifies protein which regulates cell suicide

Updated NCCN Guidelines include maintenance therapy for patients with metastatic disease

New health study reveals Ontario women less likely to receive cardiac care than men

Researchers dispel myths on increased incidence of autism disorder

UC Davis receives NFL grant to study innovative ways for knee repair

Second pivotal Phase 3 trial to evaluate investigational Lp-PLA2 inhibitor darapladib initiated

Scientists identify potential drug development target for epilepsy seizures

JMC receives NIH grant to establish center of excellence for autoimmune diseases

New research suggests cancer drug may also help patients suffering from asthma

New research shows increase risk of cardiovascular disease for people on low-carbohydrate high-fat diets

Additional data from ALS patients enrolled in confirmatory Phase III STAR trial announced

More number of obese adults are turning to bariatric surgery as a last resort, says WHO

Preliminary study shows 'mini' stem cell transplantation may safely reverse severe sickle cell disease

MLL team finds 454 Sequencing technology promising for leukemia genetic characterization

RegeneRx Biopharmaceuticals completes Phase I trial evaluating systemic administration of RGN-352

Decision Resources reports increased uptake of TNF-alpha inhibitors for Crohn's disease

Varian Medical Systems receives IDG's InfoWorld 100 Award for innovative use of IT

Novartis presents 6-month results from its EVEREST study for PCV

Preliminary data from Phase 2 clinical trial of ZFP Therapeutic program presented

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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