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Notch pathway may be a good target for drug development, study says

Working with mice, Johns Hopkins scientists who tested drugs intended to halt growth of brain cancer stem cells -- a small population of cells within tumors that perpetuate cancer growth -- conclude that blocking these cells may be somewhat effective, but more than one targeted drug attack may be needed to get the job done.

3 Apr 2010

Study could aid in developing new, effective treatments for prostate cancer

Van Andel Research Institute (VARI) scientists have determined how two proteins required for the initiation and development of prostate cancer interact at the molecular level, which could lead to improved treatments for the disease.

3 Apr 2010

RPCI researcher receives grant to explore link between race and breast cancer

Christine Ambrosone, MD, Chair of Cancer Prevention and Control at Roswell Park Cancer Institute (RPCI), has received a grant for $165,000 from the Breast Cancer Research Foundation to study the possible link between race and the possibility of being diagnosed with aggressive breast cancers.

3 Apr 2010

Study uses hESC to derive floor plate tissue

New York Stem Cell Foundation (NYSCF) Fellow, Christopher Fasano, PhD, of the New York Neural Stem Cell Institute, is lead author on a study that investigating human neural development. Dr. Fasano conducted this work while working as a post-doctoral fellow at Memorial Sloan Kettering Cancer Center in the lab of Dr. Lorenz Studer.

3 Apr 2010

A detailed review for managing solid pseudopapillary tumors

Solid pseudopapillary tumor (SPT) of the pancreas is a rare neoplasm with a low malignant potential, usually affecting young women in the second or third decade of life.

3 Apr 2010

Kinetics of T cell receptors: New findings could lead to reevaluation of earlier conclusions

T cell receptors are among the most important molecules in the immune system because of their role in recognizing the antigens that signal such threats as viruses and cancer. The receptors must also distinguish these threats from the body's own cells to avoid triggering an unwanted immune system response.

3 Apr 2010

Ultrasound and light for determining tumor's response to therapy in early stages

A biomedical scientist at Ryerson University in Toronto, Canada is exploring how ultrasound and light can be used to measure the effectiveness of cancer treatment in the early stages of therapy. By comparing high-frequency ultrasound patterns before and after treatment, doctors can potentially know within days if a tumor is responding to a prescribed therapy.

3 Apr 2010

APHON calls for improved treatment and care for young cancer patients

"Pediatric oncology teams across the county are working every day to improve the care for adolescents and young adults (AYAs) with cancer," said Deborah Echtenkamp MSN RN CPON®, president of the Association of Pediatric Hematology/Oncology Nurses (APHON). "But there is more to be done, both for AYA care and to support survivorship programs that monitor patients following treatment for childhood cancer."

3 Apr 2010

NEDA and Alliance panel explore ways to reduce negative effects of obesity and eating disorders

The television news and entertainment media are missing the mark when it comes to communicating realistic and helpful information about health and weight to Americans, according to an expert media panel assembled today at Pace University in New York City.

3 Apr 2010

New production method yields hundredsfold more ubiquitylated proteins critical for cancer research

Scientists at the University of Delaware have developed a new method for producing proteins critical to research on cancer, Alzheimer's, and other diseases.

3 Apr 2010

Lyric invisible extended wear hearing device helps judo olympian hear opponent's breathing

When Grace Jividen competed in the 1992 Olympics in Barcelona, Spain, she couldn't hear her opponent's breathing, which she believes could have given her the edge in her judo competitions. Now, the former member of the 1992 U.S. women's judo team and holder of more than 41 medals from international competitions and a sixth degree black belt has the edge she was looking for thanks to Lyric, the world's first 100 percent invisible extended wear hearing device.

3 Apr 2010

CTRC commences enrollment in Phase 2 trial of REOLYSIN combination for SCC lung cancer

A virus that destroys cancer cells but leaves normal cells unharmed may offer hope to those affected by squamous cell carcinoma of the lungs (SCC lung cancer), according to investigators from the Cancer Therapy & Research Center (CTRC) at the University of Texas Health Science Center at San Antonio. The CTRC has started patient enrollment in a US Phase 2 clinical trial using intravenous administration of REOLYSIN® in combination with carboplatin and paclitaxel in patients with SCC lung cancer.

3 Apr 2010

Young adults with hyperthyroidism face increase risk of stroke

Young adults with overactive thyroid face a 44 percent increased risk of stroke compared to those with normal thyroid function, according to a study reported in Stroke: Journal of the American Heart Association.

3 Apr 2010

Scientific American features Echo Therapeutics' non-invasive, wireless Symphony tCGM System

Echo Therapeutics, Inc., a company developing its needle-free Symphony™ tCGM System as a non-invasive, wireless, transdermal continuous glucose monitoring (tCGM) system and its Prelude™ SkinPrep System for transdermal drug delivery, announced today that its Symphony™ tCGM System has been featured in a March 31, 2010 online magazine article in Scientific American entitled "This Really Won't Hurt a Bit: Wireless Sensor Promises Diabetics Noninvasive Blood Sugar Readings," by Larry Greenemeier.

3 Apr 2010

"Mouse model" study finds LRRK2 gene mutation may cause inherited Parkinson's disease

Using new one-of-a-kind "mouse models" that promise to have a significant impact on future Parkinson's disease research, Mount Sinai School of Medicine researchers are among the first to discover how mutations in a gene called LRRK2 may cause inherited (or "familial") Parkinson's disease, the most common form of the disease.

2 Apr 2010

Variant of ATG16L1 gene associated with higher risk for Crohn's disease

The ATG16L1 gene is located on chromosome 2 and encodes a protein involved in the formation of autophagosomes during autophagy. Autophagy is a cytoplasmic process that keeps a cell stable. Hampe et al first identified ATG16L1 as a Crohn's disease (CD) susceptibility gene in 2007, and many other studies have arisen since then. However, the definite relationship of variants of ATG16L1 with IBD remains unclear.

2 Apr 2010

Multnomah Court Judge denies I-Flow's request for new trial

Judge Youlee You today denied a request by defendant I-Flow for a new trial in Multnomah County Circuit Court. The ruling follows the January 22 jury verdict against the pain pump manufacturer. Jurors awarded $5.475 million for the destruction of Portland-area resident Matthew Beale's right shoulder. They found the damage was caused by the On-Q Painbuster infusion pain pump, manufactured and marketed by I-Flow.

2 Apr 2010

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Renuka Iyer, MD, of the Department of Medicine, and Dan Iancu, MD, of the Department of Pathology and Laboratory Medicine at Roswell Park Cancer Institute (RPCI) are studying how a new test called CellSearch could be used with standard radiographic methods to monitor treatment results in patients with locally advanced or metastatic gallbladder or biliary duct cancers. The goal of the study is to see if CellSearch could predict patient response to therapy earlier than traditional measures.

2 Apr 2010

Easter Seals Bay Area urges people to support families living with autism

Ever feel compelled to help a cause you believe in, but just don't know how? By working with Easter Seals Bay Area (bayarea.easterseals.com), you can join the fight for families with autism so they can get the care, guidance and support they need, and help children with autism have the bright future that every child deserves.

2 Apr 2010

Scientists identify potential new method for treating sleeping sickness

Scientists have identified a potential new approach to treat human African trypanosomiasis (HAT), commonly known as sleeping sickness, which afflicts "tens of thousands of people in sub-Saharan Africa" annually, IRIN reports. By targeting an enzyme the sleeping sickness parasite needs in order to survive, researchers say they can kill it without causing harm to the patient (4/1).

2 Apr 2010

Medical Condition News

Notch pathway may be a good target for drug development, study says

Study could aid in developing new, effective treatments for prostate cancer

RPCI researcher receives grant to explore link between race and breast cancer

Study uses hESC to derive floor plate tissue

A detailed review for managing solid pseudopapillary tumors

Kinetics of T cell receptors: New findings could lead to reevaluation of earlier conclusions

Ultrasound and light for determining tumor's response to therapy in early stages

APHON calls for improved treatment and care for young cancer patients

NEDA and Alliance panel explore ways to reduce negative effects of obesity and eating disorders

New production method yields hundredsfold more ubiquitylated proteins critical for cancer research

Lyric invisible extended wear hearing device helps judo olympian hear opponent's breathing

CTRC commences enrollment in Phase 2 trial of REOLYSIN combination for SCC lung cancer

Young adults with hyperthyroidism face increase risk of stroke

Scientific American features Echo Therapeutics' non-invasive, wireless Symphony tCGM System

"Mouse model" study finds LRRK2 gene mutation may cause inherited Parkinson's disease

Variant of ATG16L1 gene associated with higher risk for Crohn's disease

Multnomah Court Judge denies I-Flow's request for new trial

RPCI studies potential of CellSearch test for monitoring treatment results in metastatic gallbladder patients

Easter Seals Bay Area urges people to support families living with autism

Scientists identify potential new method for treating sleeping sickness

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