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Sildenafil improves heart function in youngsters with single ventricle congenital heart disease

Heart function significantly improved in children and young adults with single ventricle congenital heart disease who have had the Fontan operation following treatment with sildenafil, a drug used to treat erectile dysfunction and pulmonary hypertension, say researchers from The Children's Hospital of Philadelphia.

18 Nov 2009

Review of the results of Phase 2b clinical trial on PASCAL announced

ARYx Therapeutics, Inc., a biopharmaceutical company, announced that a review of the results of the Phase 2b clinical trial, PASCAL, testing the efficacy and safety of ARYx’s compound for the treatment of atrial fibrillation, budiodarone, was presented today at the American Heart Association meeting in Orlando, Florida.

18 Nov 2009

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

A new study published in the current issue of Archives of Environmental & Occupational Health (vol. 64, No. 3) shows that this combination of night work, overtime and shortened sleep can contribute to the development among police officers of the metabolic syndrome, a combination of unhealthful factors that increase the risk of cardiovascular disease (CVD), primarily heart disease and stroke.

18 Nov 2009

First gene expression test for coronary artery disease

The Heart & Vascular Center of Arizona today announced the availability of Corus(TM) CAD, the first and only gene expression test to quantify the likelihood of obstructive(i) coronary artery disease (CAD) in patients with stable chest pain.

18 Nov 2009

Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease

Mount Sinai School of Medicine is one of 12 sites nationwide participating in the first Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease. The study is the first multicenter neurosurgical intervention in Alzheimer's research in the U.S.

18 Nov 2009

Family caregivers can reduce suffering in cancer patients through simple touch and massage techniques

Family caregivers can significantly reduce suffering in cancer patients at home through use of simple touch and massage techniques. These findings were recently reported at the 6th International Conference of the Society for Integrative Oncology.

18 Nov 2009

AMD: A leading cause of blindness among smokers

MD Alliance International strongly urges all smokers to participate in the Great American Smokeout on November 19 to save their eyes and protect their vision from the debilitating effects of macular degeneration.

18 Nov 2009

Maternal blood biomarkers may help predict pregnancy-induced hypertension

A new study that examines the value of maternal blood biomarkers will help identify and monitor patients at risk of developing preeclampsia and is set to change the way expectant mothers are cared for in prenatal clinics around the world.

18 Nov 2009

New encapsulated system may enable doctors to deliver anti-cancer drugs directly to tumors

An encapsulation breakthrough by researchers at the Technion-Israel Institute of Technology may enable doctors to deliver anti-cancer drugs directly to tumors over extended periods of time, while preventing the systemic side effects of chemotherapy and other current cancer treatments.

18 Nov 2009

Transplanting people's own stem cells into heart muscle lessens pain and improves ability to walk

The largest national stem cell study for heart disease showed the first evidence that transplanting a potent form of adult stem cells into the heart muscle of subjects with severe angina results in less pain and an improved ability to walk. The transplant subjects also experienced fewer deaths than those who didn't receive stem cells.

18 Nov 2009

Novel device may reduce ischemic stroke damage

Stroke researchers at the Methodist Neurological Institute in Houston are the only ones in Texas to offer a novel device that might extend the acute stroke treatment window from three hours to 24.

18 Nov 2009

Drug therapy offers substantial cost savings than angioplasty

Many patients with diabetes should forego angioplasties for heart disease and just take medicine instead, according to a new National Institutes of Health study led by Stanford University School of Medicine researcher Mark Hlatky, MD.

18 Nov 2009

American Cancer Society partners with ENTA to spread anti-smoking message among teens

The American Cancer Society and ENT and Allergy Associates, LLP (ENTA) are once again teaming up to bring a strong and relevant anti-smoking message to teens and ENTA patients through a strategic partnership that includes outreach to local high schools and patient education.

18 Nov 2009

Medtronic introduces new TSRH 3Dx Spinal System to address multiple pathologies

Medtronic, Inc., today announced the launch of the TSRH® 3Dx™ Spinal System. Designed with procedural efficiency in mind, the TSRH 3Dx Spinal System offers two screws designed to address multiple pathologies.

17 Nov 2009

Depression is as much of a risk factor for mortality as smoking, says new study

A study by researchers at the University of Bergen, Norway, and the Institute of Psychiatry (IoP) at King's College London has found that depression is as much of a risk factor for mortality as smoking.

17 Nov 2009

American Heart Association supports ‘Healthy Choices for Healthy Children legislation'

The American Heart Association is joining efforts to decrease and prevent childhood obesity through legislation that is being introduced today in the Ohio Senate and Ohio House of Representatives. The

17 Nov 2009

GlaxoSmithKline and bioMerieux to develop predictive test for breast cancer treatments

bioMerieux has signed an agreement with GlaxoSmithKline to develop a predictive test to help clinicians select the most appropriate treatment for different segments of breast cancer patients.

17 Nov 2009

Advanced BioHealing commences efficacy trial of Dermagraft in the treatment of VLUs

Advanced BioHealing, Inc. (ABH), a leader in commercializing the promise of regenerative medicine, announced that it has initiated a pivotal trial of Dermagraft® in subjects with venous leg ulcers (DEVO-Trial) to assess the product’s safety and efficacy in the promotion of healing venous leg ulcers (VLUs). Dermagraft is a bio-engineered skin substitute that assists in restoring damaged tissue and supports the body’s natural healing process.

17 Nov 2009

Genzyme and Isis Pharmaceuticals announce phase 3 study data of mipomersen

Genzyme Corp. and Isis Pharmaceuticals Inc. announced that data from the phase 3 study of mipomersen in patients with homozygous familial hypercholesterolemia (hoFH) were presented today at the American Heart Association’s Scientific Sessions.

17 Nov 2009

Alkermes commences phase 2 study of ALKS 33 in patients with alcohol dependence

Alkermes, Inc. today announced the initiation of a phase 2 clinical study of ALKS 33, an investigational oral opioid modulator for the potential treatment of alcohol dependence and other central nervous system disorders. The study will assess the safety and efficacy of multiple doses of ALKS 33 in patients with alcohol dependence and is designed to further define the clinical profile of ALKS 33.

17 Nov 2009

Medical Condition News

Sildenafil improves heart function in youngsters with single ventricle congenital heart disease

Review of the results of Phase 2b clinical trial on PASCAL announced

Combination of night work, overtime and shortened sleep can increase risk of stroke and heart disease

First gene expression test for coronary artery disease

Phase 2 clinical trial to test gene therapy treatment for Alzheimer's disease

Family caregivers can reduce suffering in cancer patients through simple touch and massage techniques

AMD: A leading cause of blindness among smokers

Maternal blood biomarkers may help predict pregnancy-induced hypertension

New encapsulated system may enable doctors to deliver anti-cancer drugs directly to tumors

Transplanting people's own stem cells into heart muscle lessens pain and improves ability to walk

Novel device may reduce ischemic stroke damage

Drug therapy offers substantial cost savings than angioplasty

American Cancer Society partners with ENTA to spread anti-smoking message among teens

Medtronic introduces new TSRH 3Dx Spinal System to address multiple pathologies

Depression is as much of a risk factor for mortality as smoking, says new study

American Heart Association supports ‘Healthy Choices for Healthy Children legislation'

GlaxoSmithKline and bioMerieux to develop predictive test for breast cancer treatments

Advanced BioHealing commences efficacy trial of Dermagraft in the treatment of VLUs

Genzyme and Isis Pharmaceuticals announce phase 3 study data of mipomersen

Alkermes commences phase 2 study of ALKS 33 in patients with alcohol dependence

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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