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Recommended supplementation not sufficient to normalise vitamin D levels in RA patients: Study

Two separate studies have shown that vitamin D deficiency is common in patients with a range of rheumatic diseases, with over half of all patients having below the 'normal' healthy levels of vitamin D (48-145 nmol/L) in their bodies. A further study assessing response to vitamin D supplementation found that taking the recommended daily dose did not normalise vitamin D levels in rheumatic disease patients.

18 Jun 2010

InteKrin Therapeutics to present INT131 SPPARM Phase 2b data at American Diabetes Association meeting

InteKrin Therapeutics Inc. announced today it will present 6 month Phase 2b clinical data for edema in diabetic patients showing differentiation for INT131, a Selective PPAR-gamma Modulator (SPPARM), from Actos® pioglitazone, at the American Diabetes Association annual meeting in Orlando, FL, Monday, June 28, 2010 at 2:45 pm EDT during the "Update on BARI 2D --Treatment of Insulin Resistance" session.

18 Jun 2010

Risk of MI increases six-fold in young women with RA: Study

Rheumatoid Arthritis patients face a two-fold increased risk of suffering a Myocardial Infarction (MI, heart attack) versus the general population, which is comparable to the increased risk of MI seen in diabetes patients, according to results of a new study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

18 Jun 2010

USFDA approves Sun Pharma's generic Xanax ANDA

Sun Pharma announced that USFDA has granted an approval for its Abbreviated New Drug Application (ANDA) to market a generic version of Xanax®, alprazolam tablets.

18 Jun 2010

Additional results from BLISS-52 Phase 3 trial of BENLYSTA for SLE to be presented at EULAR 2010

Human Genome Sciences, Inc. and GlaxoSmithKline PLC today announced the presentation of additional results from BLISS-52, one of two pivotal Phase 3 trials of BENLYSTA (belimumab) in seropositive patients with systemic lupus erythematosus. The additional data will be presented in Rome at the 2010 Congress of the European League against Rheumatism on Saturday, June 19.

18 Jun 2010

Expression of BCRP in RA patients may indicate higher disease activity, predict resistance to DMARDs

The expression of a transporter protein called the Breast Cancer Resistance Protein in rheumatoid arthritis patients may indicate higher disease activity and could be a barrier to the effectiveness of disease-modifying antirheumatic drugs, according to the results of a study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

18 Jun 2010

Interim epidemiological information on SLE patients in China presented at EULAR 2010

The Chinese Systemic Lupus Erythematosus Treatment and Research Group (CSTAR) announced interim epidemiological information on SLE patients in China today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy. Robust data on SLE patients has been scarce to date; but now CSTAR provides the first online registry of this magnitude in China. To date the registry has collated data from 2,104 SLE patients across 30 Chinese provinces.

18 Jun 2010

Hyperthermia in combination with particle therapy highlighted at DEGRO annual meeting

BSD Medical Corporation today announced that hyperthermia in conjunction with particle therapy was highlighted at the annual meeting of the German Society of Radiation Oncology, which was recently held in Magdeburg, Germany. A total of 2,500 scientists and radiation oncologists attended the meeting.

18 Jun 2010

New data shows racial-ethnic groups living in similar environment differ in cardiovascular risk profiles

Racial-ethnic groups living in a similar environment and with access to universal healthcare differed strikingly in their cardiovascular risk profiles according to new data presented today at the World Congress of Cardiology Scientific Sessions in Beijing, China.

18 Jun 2010

Physical fitness reduces metabolic risk in college students

Staying in shape may bolster the metabolic profiles of college students, even in those with higher than desirable body fat percentages. In an epidemiological study, researchers at the Friedman School of Nutrition Science and Policy at Tufts University found an association between physical fitness, body fat percentage and certain metabolic risk factors that are precursors to cardiovascular disease and Type 2 diabetes.

18 Jun 2010

Adult stem cell infusion during bypass surgery improves heart function: Study

Stem cell scientists from around the world gathered at the International Society of Stem Cell Research (ISSCR) in San Francisco to exchange information about the latest treatments with stem cells. An American company, TCA Cellular Therapy, LLC announced its FDA clinical trial results using adult stem cells in patients with history of a heart attack during open heart surgery.

18 Jun 2010

Serotonin transporter gene appears to increase one's risk for depression, PTSD: Study

There is a great deal of interest in factors that contribute to the vulnerability to developing post-traumatic stress disorder, or PTSD. One factor that appears to contribute to the heritable vulnerability to PTSD is a variation in the gene that codes for the serotonin transporter, also known as the serotonin uptake site. Having a shorter version of the serotonin transporter gene appears to increase one's risk for depression and PTSD after exposure to extremely stressful situations.

18 Jun 2010

Smoking cigarettes may influence RA disease progression: Study

Smoking cigarettes is a significant risk factor for developing rheumatoid arthritis and may have a negative impact on the effectiveness of anti-tumour necrosis factor inhibitors in RA patients taking these treatments, according to results of two studies presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

18 Jun 2010

Completion of drug analysis by PBS-Bio enables PharmaGap advance development of novel anti-cancer drug

Predictive Biomarker Sciences Inc. (PBS-Bio) has completed its first drug analysis, enabling Canadian biotech company PharmaGap Inc. to significantly advance a potentially significant anti-cancer medication.

18 Jun 2010

Special public meeting to spotlight stem cell-based therapies for ALS

Local scientists, health advocates and leaders from the California Institute for Regenerative Medicine will gather in San Diego June 23 for a special public meeting to spotlight a new University of California, San Diego grant to pursue novel, fast-tracked stem cell-based therapies for amyotrophic lateral sclerosis, or Lou Gehrig's disease.

18 Jun 2010

Study validates NT-proBNP as strong indicator for cardiovascular risk in arthritis patients

The role of N-terminal pro-B-type natriuretic peptide (NT-proBNP, a protein thought to be a regulator of cardiovascular function) as a robust, non-invasive predictor of cardiovascular (CV) risk in patients with arthritis taking cyclooxygenase inhibitors has been reinforced by the results of a multinational study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

18 Jun 2010

Offering support to partners of newly diagnosed RA patients

Partners of patients newly diagnosed with rheumatoid arthritis are equally emotionally affected by the diagnosis and go through the same grieving process as the patients themselves, according to the results of a study presented today at EULAR 2010, the Annual Congress of the European League Against Rheumatism in Rome, Italy.

18 Jun 2010

Yearlong collaborative partnership launched to reduce hospital readmissions due to heart failure

More than 5 million individuals in the United States suffer from chronic heart failure, making it one of the most common reasons for hospitalizations and readmissions. To address this costly issue, the New Jersey Hospital Association's Institute for Quality and Patient Safety this week launched a yearlong collaborative partnership to reduce hospital readmissions due to heart failure and improve the quality of healthcare in New Jersey.

18 Jun 2010

Trial eases concerns over effects of gamma secretase inhibitors for Alzheimer's disease treatment

The first trial of a new model for testing Alzheimer's treatments has reassured researchers that a promising class of drugs does not exacerbate the disease if treatment is interrupted.

18 Jun 2010

Damage to right prefrontal cortex of brain leads to deficit in intentional anticipation

Researchers of the University of Granada have demonstrated that patients who have damage to the right prefrontal cortex of the brain -the part involved in anticipation and quick reaction to stimuli- present a deficit in intentional anticipation (for example, when we put the vehicle in gear before the light turns green). However, these patients keep unintentional anticipation functions intact, which could help develop new therapies.

18 Jun 2010

Medical Condition News

Recommended supplementation not sufficient to normalise vitamin D levels in RA patients: Study

InteKrin Therapeutics to present INT131 SPPARM Phase 2b data at American Diabetes Association meeting

Risk of MI increases six-fold in young women with RA: Study

USFDA approves Sun Pharma's generic Xanax ANDA

Additional results from BLISS-52 Phase 3 trial of BENLYSTA for SLE to be presented at EULAR 2010

Expression of BCRP in RA patients may indicate higher disease activity, predict resistance to DMARDs

Interim epidemiological information on SLE patients in China presented at EULAR 2010

Hyperthermia in combination with particle therapy highlighted at DEGRO annual meeting

New data shows racial-ethnic groups living in similar environment differ in cardiovascular risk profiles

Physical fitness reduces metabolic risk in college students

Adult stem cell infusion during bypass surgery improves heart function: Study

Serotonin transporter gene appears to increase one's risk for depression, PTSD: Study

Smoking cigarettes may influence RA disease progression: Study

Completion of drug analysis by PBS-Bio enables PharmaGap advance development of novel anti-cancer drug

Special public meeting to spotlight stem cell-based therapies for ALS

Study validates NT-proBNP as strong indicator for cardiovascular risk in arthritis patients

Offering support to partners of newly diagnosed RA patients

Yearlong collaborative partnership launched to reduce hospital readmissions due to heart failure

Trial eases concerns over effects of gamma secretase inhibitors for Alzheimer's disease treatment

Damage to right prefrontal cortex of brain leads to deficit in intentional anticipation

How real-time off-gas analysis improves fermentation process control

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AI-powered analytics and experimental validation

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