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Tenecteplase injection after clot removal improves stroke recovery

Removing a blood clot from a large brain artery, then injecting the clot-dissolving drug tenecteplase into the artery resulted in stroke survivors being more likely to have better function 90 days after their stroke than those receiving standard clot removal, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

8 Feb 2025

Clot-busting drug alteplase shows promise for stroke treatment up to 24 hours after onset

The clot-dissolving medication, alteplase, improved stroke patients' recovery by more than 50% when given up to 24 hours after the beginning of an ischemic stroke, according to preliminary late-breaking science presented today at the American Stroke Association's International Stroke Conference 2025.

8 Feb 2025

Evaluating the safety and efficacy of Tendvia mechanical thrombectomy for acute pulmonary embolism

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Mechanical thrombectomy is effective and safe for treating pulmonary embolism (PE).

8 Feb 2025

Immune gene expression changes in myocardial infarction revealed through bioinformatics

Announcing a new article publication for Cardiovascular Innovations and Applications journal. This study was aimed at exploring immune-related genes and their expression changes in myocardial infarction (MI) through comprehensive bioinformatics methods and validating these genes as potential diagnostic and therapeutic targets.

8 Feb 2025

Mitochondrial damage linked to beta-cell dysfunction in type 2 diabetes

Mitochondria are essential for generating energy that fuels cells and helps them function.

8 Feb 2025

UCLA Health launches study on ketogenic diet for bipolar disorder in youth

UCLA Health is set to begin a multi-site pilot study to explore whether a ketogenic diet, when combined with mood stabilizing medications, helps stabilize mood symptoms in teenagers and young adults who have bipolar disorder.

8 Feb 2025

Understanding the role of alternative splicing in cardiovascular diseases

Announcing a new article publication for Cardiovascular Innovations and Applications journal. Alternative splicing (AS), a critical process for gene expression regulation, allows a single precursor RNA to produce multiple transcript variants.

8 Feb 2025

Gene therapy developments and obstacles for neurologic disorders

Announcing a new article publication for BIO Integration journal. Neurologic disorders currently affect approximately 100 million people worldwide.

8 Feb 2025

$New clinical trial aims to improve outcomes for older adults with hip fractures$

New clinical trial aims to improve outcomes for older adults with hip fractures

Hip fractures in older adults can lead to serious complications, disability and even death. Traditionally, orthopaedic surgeons have repaired a common fracture of the upper part of the thigh bone, or femur, near the hip using screws and plates to piece together slightly separated pieces of bone.

8 Feb 2025

Living in disadvantaged areas reduces ALS survival time by over 30%

Living in a disadvantaged community may decrease the length of time a person can survive with amyotrophic lateral sclerosis, or ALS, by over 30%, a Michigan Medicine-led study suggests.

7 Feb 2025

Electronic monitoring boosts well-being and delays symptom deterioration in cancer patients

People with metastatic cancer who regularly report their symptoms via a home-based electronic monitoring system experienced improved quality of life, clinical outcomes and well-being, as well as fewer emergency department visits than those who didn't file reports.

7 Feb 2025

Modifying biomaterials may lead to more effective cancer therapies

Modifying the physical characteristics of microscopic biomaterials to interact seamlessly with the body's tissues could unlock safer and more effective cancer treatments, according to Virginia Tech researchers at the Fralin Biomedical Research Institute at VTC.

7 Feb 2025

Vision loss risks in patients using popular GLP-1 medications raise concerns

A small percentage of patients taking the extraordinarily popular GLP-1 medications have experienced vision problems, but a direct causal link with the drugs has not been established. That is the conclusion of a retrospective study published online on Jan. 30 in JAMA Ophthalmology.

7 Feb 2025

Low income linked to higher mortality risk in young adults with diabetes

The research team of Professor Sin Gon Kim and Professor Nam Hoon Kim of department of internal medicine (Endocrinology and Metabolism) of Korea University Anam Hospital, and Professor Ji Yoon Kim of Samsung Medical Center confirmed that young adults with T2D with low income have 3 times higher mortality risk than those with high income.

7 Feb 2025

American Heart Association highlights cardiovascular health disparities in Black communities

The American Heart Association's 2025 Heart Disease and Stroke Statistical Update reports that while progress has been made in reducing cardiovascular and cerebral health disparities, Black communities in the United States still face disproportionately higher risk of heart disease, stroke and hypertension.

7 Feb 2025

Liver graft preservation methods alter microbiota composition after transplantation

End-stage liver disease is associated with disruptions in gut microbiota composition and function, which may facilitate gut-to-liver bacterial translocation, impacting liver graft integrity and clinical outcomes following liver transplantation.

7 Feb 2025

Insilico Medicine develops highly selective FGFR2/3 dual inhibitor for cancer treatment

Fibroblast growth factor receptors (FGFRs) are critical drivers of oncogenesis in various solid tumors, including urothelial carcinoma, hepatocellular carcinoma, ovarian cancer and lung adenocarcinoma.

7 Feb 2025

Targeting ELK3 could offer new therapy for rheumatoid arthritis

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.

7 Feb 2025

New 3D bioprinted gastric cancer model predicts drug responses

A collaborative research team led by Professor Jinah Jang from the Department of Mechanical Engineering and the Department of Creative IT Engineering at POSTECH (Pohang University of Science and Technology) and Professor Charles Lee from The Jackson Laboratory for Genomic Medicine in the United States has successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments.

7 Feb 2025

New gene modification enhances CAR-T cell effectiveness against cancer

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying a specific gene improves the ability of immune cells to combat cancer for an extended period, potentially reducing the chance of cancer recurring.

7 Feb 2025