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Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Mount Sinai researchers have identified a key driver of a blood vessel disorder known as fibromuscular dysplasia (FMD) which affects up to five percent of the adult population and can lead to high blood pressure, heart attack, or stroke.

14 Sep 2024

Scientists develop selective therapy for tau tangles

Scientists have developed new potential therapies that selectively remove aggregated tau proteins, which are associated with Alzheimer's disease, and improve symptoms of neurodegeneration in mice.

14 Sep 2024

New insight into the causes of autoimmune diseases

Autoimmune diseases are widespread and notoriously difficult to treat. In part, this is because why the immune system attacks its own tissues in patients with these conditions remains poorly understood.

14 Sep 2024

Real-world data reveals factors associated with long-term weight loss in obesity

A Cleveland Clinic study identified key factors that can impact the long-term weight loss of patients with obesity who were prescribed injectable semaglutide or liraglutide for the treatment of type 2 diabetes or obesity. The study was published in JAMA Network Open.

14 Sep 2024

Study reveals how SARS-CoV-2 triggers diabetes by destroying pancreatic cells

Researchers from Weill Cornell Medicine have used a cutting-edge model system to uncover the mechanism by which SARS-CoV-2, the virus that causes COVID-19, induces new cases of diabetes, and worsens complications in people who already have it.

13 Sep 2024

Study sheds light on potential demand for psilocybin-assisted therapy for depression in the U.S.

In the wake of mounting evidence for the efficacy of psychedelic-assisted therapies, the U.S. Food and Drug Administration (FDA) is considering approving psilocybin, the active ingredient in "magic mushrooms," for treating depression in the near future.

13 Sep 2024

Huntsman Cancer Institute celebrates 25 years of innovations in cancer research and care

On September 13, 2024, Huntsman Cancer Institute at the University of Utah (the U), the National Cancer Institute-designated cancer center for the Mountain West, celebrates 25 years of groundbreaking cancer research, education, and patient care.

13 Sep 2024

Semaglutide and tirzepatide significantly improve weight loss and glycemic control in type 1 diabetes

Semaglutide and tirzepatide treatment lead to significant weight loss and improve blood sugar control in individuals with type 1 diabetes (T1D) who are living with overweight or obesity, new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Madrid, Spain (9-13 September) has found.

13 Sep 2024

Low manganese levels found to worsen inflammatory bowel conditions

Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of the micronutrient can exacerbate intestinal injury and inflammation.

13 Sep 2024

PPARs and PROTACs: A new strategy in cancer therapeutics

The growing challenge in cancer therapy lies in overcoming tumor heterogeneity, drug resistance, and associated side effects.

13 Sep 2024

Understanding sex-specific patterns of melanoma development

Melanoma rates differ consistently between men and women in terms of the ages at which melanomas occur and the locations on the body where they occur.

13 Sep 2024

New initiative aims to set gold standards for palliative care training

Palliative care aims to improve the quality of life of patients and their families facing problems associated with life-threatening illnesses.

13 Sep 2024

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

A new biomarker makes it easier to distinguish between Alzheimer's and primary tauopathy.

13 Sep 2024

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Gastric cancer remains a formidable adversary, ranking as the fifth most common cancer and the third-leading cause of cancer-related deaths worldwide, with over 1,000,000 new cases and close to 770,000 deaths each year.

13 Sep 2024

Advanced insulin pump technology improves diabetes management for marathon runners

A series of case reports to be presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Madrid (9-13 Sept), describe how a technology giving insulin doses informed by an insulin pump algorithm helped three adults with type 1 diabetes better manage their blood sugars enabling them to lead more active lives, and even run marathons.

13 Sep 2024

New blood test achieves 98% accuracy in diagnosing ALS

A highly accurate diagnostic blood test has been developed for amyotrophic lateral sclerosis (ALS), a progressive neurodegenerative disease that effects neurons in the brain and spinal cord.

13 Sep 2024

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

In an international multicenter randomized phase 3 clinical trial led by Dana-Farber Cancer Institute, researchers tested the addition of the immune checkpoint inhibitor (ICI) nivolumab to treatment with tivozanib for patients with advanced clear cell renal cell carcinoma, a form of kidney cancer.

13 Sep 2024

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Insilico Medicine("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced the nomination of ISM2196, an AI-driven, potential best-in-class small molecule WRN inhibitor targeting advanced metastatic microsatellite instability (MSI) cancers guided by synthetic lethality strategy.

13 Sep 2024

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

A new editorial was recently published in Oncotarget's Volume 15, on July 10, 2024, entitled, "The advances in targeting CD47/SIRPα "do not eat me" axis and their ongoing challenges as an anticancer therapy."

13 Sep 2024

Novel drug delivery system aims to prevent hearing loss from cisplatin chemotherapy

The chemotherapy drug cisplatin is a lifesaver for many adults and children diagnosed with cancer, but it often causes hearing loss, a side effect that can diminish quality of life following treatment.

13 Sep 2024

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Medical Condition News

Mount Sinai researchers uncover genetic basis of fibromuscular dysplasia

Scientists develop selective therapy for tau tangles

New insight into the causes of autoimmune diseases

Real-world data reveals factors associated with long-term weight loss in obesity

Study reveals how SARS-CoV-2 triggers diabetes by destroying pancreatic cells

Study sheds light on potential demand for psilocybin-assisted therapy for depression in the U.S.

Huntsman Cancer Institute celebrates 25 years of innovations in cancer research and care

Semaglutide and tirzepatide significantly improve weight loss and glycemic control in type 1 diabetes

Low manganese levels found to worsen inflammatory bowel conditions

PPARs and PROTACs: A new strategy in cancer therapeutics

Understanding sex-specific patterns of melanoma development

New initiative aims to set gold standards for palliative care training

New biomarker helps differentiate Alzheimer’s from primary 4-repeat tauopathies

Breakthrough study sheds light on mechanisms behind the spread of gastric cancer to the peritoneum

Advanced insulin pump technology improves diabetes management for marathon runners

New blood test achieves 98% accuracy in diagnosing ALS

Trial finds no benefit of adding nivolumab to tivozanib for advanced kidney cancer

ISM2196: A promising AI-developed WRN inhibitor for advanced metastatic cancers

Advances in targeting the CD47/SIRPα "do not eat me" pathway for cancer therapy

Novel drug delivery system aims to prevent hearing loss from cisplatin chemotherapy

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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