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Intranasal vaccine shows broad SARS-CoV-2 variant protection

Study demonstrates that a single-dose intranasal live-attenuated vaccine, CDO-7N-1, provides broad protection against SARS-CoV-2 and its variants by inducing potent immune responses, including neutralizing antibodies and T-cell activity, in animal models.

1 Sep 2024

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

Mitral transcatheter edge-to-edge repair (M-TEER) reduced cardiovascular death and heart failure (HF)-related hospitalizations with improved health status in patients with HF and moderate to severe functional mitral regurgitation (FMR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Timing of blood pressure medication administration does not affect outcomes

Evening administration of blood pressure (BP)-lowering medications did not reduce the risk of cardiovascular events or death compared with morning administration, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Low-dose triple-pill combination outperforms standard care for blood pressure control in Nigerian adults

A low-dose triple single-pill combination-based protocol achieved better blood pressure (BP) control than a standard-care protocol in Black African Nigerian adults with uncontrolled hypertension, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

There was no difference in efficacy between transcatheter edge-to-edge repair (TEER) and surgery in patients with secondary mitral regurgitation (MR), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

No-touch graft harvesting shows no advantage over conventional technique in CABG

No-touch graft harvesting did not appear to be beneficial compared with the conventional technique for coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

T-TEER shows promising outcomes in severe tricuspid regurgitation patients after one year

Tricuspid transcatheter edge-to-edge repair (T-TEER) significantly reduced the severity of secondary tricuspid regurgitation and improved quality of life after 1 year, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Research suggests flexible approach to antiplatelet management after drug-eluting stent implantation

Among patients undergoing non-cardiac surgery more than 1 year after coronary drug-eluting stent (DES) implantation, there was no difference with respect to ischaemic outcomes or major bleeding between perioperative aspirin monotherapy and receiving no antiplatelet therapy, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TAVI outperforms surgery in reducing complications for women with severe aortic stenosis

Transcatheter aortic valve implantation (TAVI) was superior to surgical aortic valve replacement for reducing death, stroke or rehospitalization in women with severe aortic stenosis, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

Study finds no added benefit to routine potassium supplementation after CABG

For the prevention of new-onset atrial fibrillation (AF) after isolated coronary artery bypass graft (CABG) surgery, giving potassium supplements only when levels dropped below the lower limit of normal was non-inferior to routinely supplementing potassium to the upper limit of normal, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TAVI patients show no benefit from continuing oral anticoagulants

There was no apparent benefit to continuing oral anticoagulants compared with interruption in patients undergoing transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

TAVI patients with coronary artery disease can derive benefits from percutaneous coronary intervention

Performing percutaneous coronary intervention (PCI) significantly improved outcomes in patients with stable coronary artery disease (CAD) and severe aortic stenosis selected for transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

1 Sep 2024

New study highlights potential of childhood immunization against HIV

Research at Weill Cornell Medicine suggests that childhood immunization against HIV could one day provide protection before risk of contracting this potentially fatal infection dramatically increases in adolescence.

30 Aug 2024

Semaglutide cuts death rates from cardiovascular disease and COVID-19

Patients taking semaglutide injections are less likely to die of any cause, including from cardiovascular disease and infections like COVID-19, an international study led by researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, finds.

30 Aug 2024

Research highlights need for clear guidelines on healthy hydration

Adequate water intake is essential for human health and well-being. But around the world, the consumption of sugary beverages has risen and accelerated health challenges including obesity, Type 2 diabetes, heart disease and tooth decay.

30 Aug 2024

Tau protein shows unexpected benefits in mitigating brain damage

A study by researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital, reveals that the protein Tau – a key player implicated in several neurodegenerative conditions including Alzheimer's disease – also plays a positive role in the brain.

30 Aug 2024

Clonal hematopoiesis identified as new risk factor for atherosclerosis

To the known risk factors for cardiovascular disease-;high blood pressure, high cholesterol, diabetes, overweight and obesity, smoking, and physical inactivity-;a new one has to be added: clonal hematopoiesis.

30 Aug 2024

Medicare Advantage enrollment does not affect frailty trajectories

Enrollment in Medicare Advantage (MA) plans is not associated with altered frailty trajectories compared with enrollment in Traditional Medicare (TM), according to research published today in JAMA Network Open.

30 Aug 2024

Hope proves more effective than mindfulness for managing work stress

A recent study finds that hope appears to be more beneficial than mindfulness at helping people manage stress and stay professionally engaged during periods of prolonged stress at work.

30 Aug 2024

Interrupting beta-blockers after myocardial infarction shows no advantage

The cardiovascular safety of interrupting beta-blocker could not be shown in comparison to continuation in patients with a history of myocardial infarction (MI) and there was no benefit to the patients' quality of life, according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.

30 Aug 2024

Medical Research News

Intranasal vaccine shows broad SARS-CoV-2 variant protection

RESHAPE-HF2 trial shows M-TEER as effective treatment for functional mitral regurgitation

Timing of blood pressure medication administration does not affect outcomes

Low-dose triple-pill combination outperforms standard care for blood pressure control in Nigerian adults

MATTERHORN trial finds TEER non-inferior to surgery for secondary mitral regurgitation

No-touch graft harvesting shows no advantage over conventional technique in CABG

T-TEER shows promising outcomes in severe tricuspid regurgitation patients after one year

Research suggests flexible approach to antiplatelet management after drug-eluting stent implantation

TAVI outperforms surgery in reducing complications for women with severe aortic stenosis

Study finds no added benefit to routine potassium supplementation after CABG

TAVI patients show no benefit from continuing oral anticoagulants

TAVI patients with coronary artery disease can derive benefits from percutaneous coronary intervention

New study highlights potential of childhood immunization against HIV

Semaglutide cuts death rates from cardiovascular disease and COVID-19

Research highlights need for clear guidelines on healthy hydration

Tau protein shows unexpected benefits in mitigating brain damage

Clonal hematopoiesis identified as new risk factor for atherosclerosis

Medicare Advantage enrollment does not affect frailty trajectories

Hope proves more effective than mindfulness for managing work stress

Interrupting beta-blockers after myocardial infarction shows no advantage

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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