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Addressing the gender gap in substance abuse treatment

Woman with opioid use disorder and who are also involved with the criminal legal system face unique challenges and stigmas that may keep them from seeking substance use treatment and harm reduction tools that could prevent overdose deaths, according to new research led by a team from Penn State.

28 Aug 2024

Study identifies genetic cause of severe seizures in children

Shortly after Kelly Cervantes' daughter Adelaide was born, she started having terrible seizures. Doctors were unable to give her a solution, or even a cause.

28 Aug 2024

Benefits of less intensive stem cell transplants for sickle cell disease

So-called low-intensity blood stem cell transplants, which use milder conditioning agents than standard stem cell transplants, do not appear to damage the lungs and may help improve lung function in some patients with sickle cell disease (SCD), according to a three-year study of adults who underwent the procedure at the National Institutes of Health (NIH).

28 Aug 2024

CNRS scientists uncover activation mechanism of bemnifosbuvir

CNRS Scientists have deciphered the activation pathway of bemnifosbuvir, a drug candidate initially in development to treat hepatitis C virus (HCV). The findings of the research team, led by CNRS scientists, unlock new opportunities to boost the efficacy of this type of drug against other RNA viruses, such as the ones that cause Covid-19 and dengue fever.

28 Aug 2024

Novel biochip diagnoses deadly brain cancer in under an hour

Researchers at the University of Notre Dame have developed a novel, automated device capable of diagnosing glioblastoma, a fast-growing and incurable brain cancer, in less than an hour. The average glioblastoma patient survives 12-18 months after diagnosis.

28 Aug 2024

PET imaging and proteomics reveal distinct protein signatures in Alzheimer's disease progression

Researchers used PET imaging and proteomic analysis of cerebrospinal fluid to study amyloid β and tau tangle loads in Alzheimer's patients, identifying 127 proteins linked to disease progression. The findings highlight distinct molecular pathways and potential therapeutic targets.

28 Aug 2024

Analysis reveals viral shift behind COVID-19 pandemic end

New analysis suggests that a dramatic drop in deaths from COVID-19 between 2022 and 2023 could be attributed to an abrupt phase transition in the molecular structure of the virus' spike protein.

28 Aug 2024

Deep learning reveals disparities in brain aging across Latin America and the Caribbean

Study reveals that socioeconomic inequality, pollution, and health disparities significantly contribute to brain-age gaps, with Latin American and Caribbean populations, especially women and those with cognitive impairments, being most affected.

28 Aug 2024

New test detects cancer risk in type 2 diabetes patients

Individuals with type 2 diabetes who are at higher risk of certain cancers could be identified by a simple blood test, this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) will hear.

28 Aug 2024

Zbtb18 regulates cKit expression for HSC self renewal

The study addresses the complex regulation of HSCs, highlighting p21's multifunctional nature beyond cell cycle control. Through the use of p21-tdTomato mice, researchers differentiate between p21-tdT+ and p21-tdT− HSCs. Results show that p21-tdT+ HSCs display increased self-renewal and reconstitution abilities. Zbtb18, upregulated in p21-tdT+ HSCs, is crucial for their repopulation capability. p21 interacts with ZBTB18 to suppress cKit, influencing HSC self-renewal.

28 Aug 2024

LncRNA ZNF593-AS offers hope for heart disease treatment

The research presented in the article delves into the regulatory role of the long non-coding RNA (lncRNA) ZNF593-AS in cardiac hypertrophy and myocardial remodeling, processes that are pivotal in the progression of heart failure and other cardiovascular diseases. The study uncovers how ZNF593-AS exerts its inhibitory effects by upregulating the expression of Mitofusin 2 (Mfn2), a protein known for its role in the regulation of mitochondrial dynamics and cellular metabolism.

28 Aug 2024

$120 million gift boosts UCLA’s efforts in immunotherapy and innovation

UCLA has received a $120 million commitment from surgeon, inventor and philanthropist Dr. Gary Michelson and his wife, Alya, to kick-start the California Institute for Immunology and Immunotherapy, an innovative public-private partnership aimed at spurring breakthrough discoveries that prevent and cure diseases and catalyze economic growth and innovation in Los Angeles.

27 Aug 2024

Maternal prenatal smoking linked to poor academic outcomes in children

Smoking harms almost every part of your body. But if you smoke when pregnant, the toxic chemicals in tobacco will also harm your unborn baby, with new research showing that it could lead to reduced academic outcomes at school.

27 Aug 2024

Simple intervention offers relief for burned-out nurses in Missouri

Even before the coronavirus pandemic, high rates of burnout and staffing shortages plagued the nursing industry, primarily because of the stressful demands of the job.

27 Aug 2024

Healthcare workers unprepared for mpox outbreak due to knowledge gaps and vaccine inequity

Research highlights significant gaps in healthcare workers' knowledge of mpox during the 2022-2023 outbreaks, emphasizing the need for better global preparedness and equitable vaccine access.

27 Aug 2024

First comprehensive description of neuropathic pain experiences among SCI athletes

With the Paris 2024 Paralympic Games just around the corner, the extensive training and the sacrifices athletes make to compete at the games take centre stage.

27 Aug 2024

ChatGPT delivers the most accurate vasectomy information, outperforming Copilot and Gemini

Research shows ChatGPT outperforms Google Bard and Bing Chat in accurately answering vasectomy-related questions, highlighting its potential in healthcare education.

27 Aug 2024

SARS-CoV-2 evolves differently in the brain, revealing critical insights into viral tropism

Study investigates the evolution of SARS-CoV-2 within the central nervous system (CNS) compared to the lungs in mice, revealing higher viral divergence in the CNS and highlighting the critical role of the furin cleavage site (FCS) in viral tropism and compartmentalization.

27 Aug 2024

Improved IVF success with the Mediterranean diet, study shows

Review highlights that adherence to the Mediterranean diet may improve clinical pregnancy and live birth rates in couples undergoing assisted reproduction, though findings are inconsistent, and more research is needed.

27 Aug 2024