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Study links OCD improvement to brain activity shift

A recent study from Baylor College of Medicine and Texas Children's Hospital has identified a specific neural activity pattern as a novel biomarker to accurately predict and monitor the clinical status of individuals with obsessive-compulsive disorder (OCD) who have undergone deep brain stimulation (DBS), a rapidly emerging therapeutic approach for severe psychiatric disorders. The study, led by led by Drs. Sameer Sheth and Wayne Goodman along with co-lead authors, Drs. Nicole Provenza, Sandy Reddy, and Anthony Allam, was published in Nature Medicine.

13 Jul 2024

Mice experiment mimicking foster care raises ethical concerns

Tom Green County District Court Judge Barbara L. Walther ruled Thursday, July 11, 2024, that Angelo State University must release public records relating to an experiment conducted on dozens of mice that resulted in the animals' unnecessary suffering and death, reportedly to study the impact of the foster care system on human children.

13 Jul 2024

Gene editing silences mutant microRNA, restores hearing in adult mice

Researchers have used gene editing to restore hearing in adult mice with a type of inherited hearing loss. They showed that shutting down a damaged copy of a gene called a microRNA (miRNA) enabled the animals to regain hearing. The approach by a research team supported by the National Institutes of Health (NIH), reported in Science Translational Medicine, may eventually lead to potential treatments for inherited hearing loss in people.

13 Jul 2024

OHStat guidelines emphasize clinically meaningful data in oral health research

The International Association for Dental, Oral, and Craniofacial Research (IADR) and the American Association for Dental, Oral, and Craniofacial Research (AADOCR) have announced the publication of revised guidelines for adequately reporting findings from oral health research. Overviews and explanations of the new guidelines, called the "OHStat Guidelines," will be published in an upcoming issue of Journal of Dental Research as part of a collaborative effort with The Angle Orthodontics, Journal of Endodontics, Journal of the American Dental Association, and Journal of Oral Maxillofacial Surgery. Additionally, a companion paper will be published in an upcoming issue of JDR Clinical & Translational Research.

13 Jul 2024

New threshold for CXCL13 concentration revolutionizes neuroborreliosis diagnosis

A newly defined threshold for the concentration of the cytokine CXCL13 may improve the diagnosis of neuroborreliosis.

13 Jul 2024

Simple measures can help address malnutrition in elderly care

As many as half of all patients admitted to hospital and other healthcare facilities are malnourished. This has serious consequences for the individual in terms of unnecessary suffering, poorer quality of life and mortality.

12 Jul 2024

Priority pathogens selected for wastewater surveillance during Paris 2024 Olympic and Paralympic Games

The study by researchers from the French national public health institute aimed to identify priority pathogens that could be suitable for wastewater surveillance (WWS) during the Paris 2024 Olympic and Paralympic Games taking place from 26 July to 11 August and 28 August to 8 September, respectively.

12 Jul 2024

Technology-assisted therapy for kids and young people is as effective as traditional face-to-face therapy

Using technology to deliver therapy for children and young people is as effective as traditional face-to-face therapy, according to new research.

12 Jul 2024

Researchers identify brain region that tunes hearing to contextual needs

Have you ever noticed how you can suddenly hear your refrigerator humming in the background when you focus on it? Or how the sound of your name instantly catches your attention even in a noisy crowd?

12 Jul 2024

ECHO study sheds light on how neighborhood environment influenced child's well-being amid pandemic

The COVID-19 pandemic significantly disrupted daily life and has raised concerns about its impact on children's well-being.

12 Jul 2024

Digital contact tracing data reveals detailed epidemic patterns in England and Wales

Data from digital contact tracing, using examples from the National Health Service (NHS) COVID-19 app for England and Wales, has revealed epidemic dynamics in unprecedented detail.

12 Jul 2024

Short and long sleep duration linked to microvascular disease in newly diagnosed diabetics

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) (Madrid, 9-13 September) shows that people recently diagnosed with diabetes who experience short or long sleep duration are more likely to experience microvascular disease (damage to the small blood vessels), which could ultimately lead to more serious complications.

12 Jul 2024

Over-the-counter nasal sprays cut respiratory infections by 20%, study finds

Widely available over-the counter nasal sprays could keep upper respiratory tract infections - like colds, chest infections, flu, sore throat, and sinus infections - at bay, and prevent full-blown symptoms from developing, one of the largest trials to date to test their effectiveness finds.

12 Jul 2024

Study identifies RFC4 as key player in nasopharyngeal carcinoma

Lichuan Wu et al., at Medical College of Guangxi University, China, presented a comprehensive study on the role of replication factor C subunit 4 (RFC4) in nasopharyngeal carcinoma (NPC), a type of epithelial cancer commonly associated with Epstein-Barr virus infection.

12 Jul 2024

Novel DNA aptamers of melanopsin developed to regulate circadian rhythm

DNA aptamers of melanopsin that regulate the clock hands of biological rhythms were developed by the Toyohashi University of Technology and the National Institute of Advanced Industrial Science and Technology (AIST) group.

12 Jul 2024

Study finds racial and ethnic disparities in postpartum pain medication

Inequities in pain medication treatment received postpartum, after giving birth, were found in a Cedars-Sinai study of 18,000 women. The disparities were observed even among patients reporting the highest pain levels.

12 Jul 2024

Researchers develop a simple new way to store, identify, and share phages

The great promise of bacteriophages is that they naturally destroy bacteria, often in situations where antibiotics fail.

12 Jul 2024

Neighborhood disadvantage linked to higher expression of stress-related genes in prostate tumors

Those living in disadvantaged neighborhoods have significantly higher activity of stress-related genes, new research suggests, which could contribute to higher rates of aggressive prostate cancer in African American men.

12 Jul 2024

Understanding the connection between autistic traits and board gaming

Board gaming is a growing industry, and anecdotally popular among people who display autistic traits.

12 Jul 2024

Study reveals potential cognitive benefits of antidiabetic drugs

Investigators analyzing the potential cognitive effects of antidiabetic medications in records of more than 1.5 million patients with type 2 diabetes mellitus (T2DM) found risks of dementia and Alzheimer's disease (AD) were significantly lower in patients treated with metformin and sodium glucose co-transporter-2 inhibitors (SGLT-2i) compared to other antidiabetic drugs.

12 Jul 2024