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Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Researchers from the University of Missouri School of Medicine found that a targeted gene therapy may make acute myeloid leukemia (AML) more sensitive to chemotherapy, while also protecting the heart against toxicity often caused by cancer treatments.

27 Jun 2024

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Results from a new study led by researchers at The University of Texas MD Anderson Cancer Center support standard use of the more precise intensity-modulated radiotherapy (IMRT) over the alternative 3D-conformal radiotherapy (3D-CRT) for patients with unresectable, locally advanced non-small cell lung cancer (NSCLC).

27 Jun 2024

Study identifies mechanism that impedes the effectiveness of melanoma therapies

In many cases of malignant melanoma, the effect of targeted treatment is lost over time. A research team from UZH and USZ has now discovered that a factor secreted by tumor cells is responsible for the resistance.

27 Jun 2024

Study reveals mental health challenges among LGBTQ+ farmers in the U.S.

LGBTQ+ people involved in U.S. farm work are over three times more likely to experience depression and suicidal intent and about two and a half times more likely to experience anxiety than the general population.

27 Jun 2024

$Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers$

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Patients with treatment-refractory cancers who received eligibility and testing waivers to participate in a large basket/umbrella oncology trial had similar rates of clinical benefit and adverse events as patients who participated in the trial without waivers.

27 Jun 2024

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Schizophrenia is a complicated mental health disorder accompanied by wide range of symptoms such as hallucinations, impaired cognitive ability, and disorganized speech or behavior.

27 Jun 2024

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

Treatment of gastrointestinal (GI) cancers is catching up with other areas of oncology and offering patients better prospects for survival and quality of life, but a significant uptick in early-onset cases is raising new questions about effective prevention, diagnosis and treatment.

27 Jun 2024

Fighting cancer with nanoparticles

Nanoparticles may be the future of the fight against pancreatic cancer, but also tumours that currently have no cure options. A video news release provides a synthesis of the ULISES project milestones.

27 Jun 2024

Chronic loneliness associated with higher stroke risk independent of depressive symptoms or social isolation

Researchers determined the relationship between loneliness and incident stroke risk in the United States.

27 Jun 2024

AI breakthrough: Speech analysis predicts Alzheimer's progression with 78.5% accuracy

A method for predicting Alzheimer’s disease (AD) progression.

27 Jun 2024

Diabetes decoded: How your gut microbiome influences disease risk

How microbial features and functions specific to subspecies and strains contribute to the pathological mechanisms of type 2 diabetes.

27 Jun 2024

New-onset anxiety in adults aged 50+ doubles risk of developing Parkinson's disease

Researchers investigated Parkinson's disease (PD) risk among individuals with new-onset anxiety and associated risk factors.

27 Jun 2024

Study shows high rates of unrecognized heart valve disease in healthy seniors

The sheer scale of undiagnosed heart valve disease in our ageing population has been revealed for the first time, thanks to new research led by the University of East Anglia.

27 Jun 2024

Study identifies key neurons controlling threat response and escape in mice

Neuroscientists have discovered how the brain bidirectionally controls sensitivity to threats to initiate and complete escape behaviour in mice. These findings could help unlock new directions for discovering therapies for anxiety and post-traumatic stress disorder (PTSD).

27 Jun 2024

Cell division's hidden safety mechanism may influence cancer growth

Before a cell commits fully to the process of dividing itself into two new cells, it may ensure the appropriateness of its commitment by staying for many hours-;sometimes more than a day-;in a reversible intermediate state, according to a discovery by researchers at Weill Cornell Medicine. Their revelation of this fundamental feature of biology includes details of its mechanisms and dynamics, which may inform the development of future therapies targeting cancers and other diseases.

27 Jun 2024

New electrospinning innovations transform wearable and implantable medical devices

In a groundbreaking advancement that could reshape the landscape of precise medicine, researchers from the Beijing Institute of Technology and Rutgers University have unveiled a series of innovative electrospinning techniques capable of significantly enhancing the functionality and effectiveness of medical devices. This pioneering study, recently published in the Cyborg Bionic Systems journal, promises to revolutionize the creation and implementation of nano/microrobots, wearable/implantable biosensors, and organ-on-chip systems.

27 Jun 2024

Amorphous calcium phosphate drives aortic valve stiffening

The human body has sophisticated defenses against the deposition of calcium minerals that stiffen heart tissues, researchers at the University of Illinois Urbana-Champaign and collaborators at UCLA Health and the University of Texas at Austin found in a new study that provides the first detailed, step-by-step documentation of how calcification progresses.

27 Jun 2024

A unifying marker streamlines macrophage research across age and sex

Macrophages play a critical role in the immune system by fighting infections and aiding in tissue repair. Understanding how these cells are activated in different scenarios is important for developing new medical treatments. However, identifying and studying macrophage activation has been challenging due to the complex nature of these cells and their responses.

27 Jun 2024

Researchers identify key players in abnormal bone differentiation

A study conducted by researchers at Baylor College of Medicine and collaborating institutions reveals the molecular events leading to osteogenesis imperfecta type V, a form of brittle bone disease caused by a mutation in the gene IFITM5.

27 Jun 2024

Early diagnosis key in combating the deadly effects of AL amyloidosis

AL (immunoglobulin light chain) amyloidosis is a rare disease that often results in progressive organ dysfunction, organ failure and eventual death.

27 Jun 2024

Medical Research News

Targeted gene therapy may reduce AML burden and protect the heart from cardiotoxicity

Precise intensity-modulated radiotherapy outperforms 3D-CRT in advanced lung cancer

Study identifies mechanism that impedes the effectiveness of melanoma therapies

Study reveals mental health challenges among LGBTQ+ farmers in the U.S.

Assessing clinical benefit and safety in trial waivers for treatment-refractory cancers

Discovery of nanoparticle-based drug delivery system could revolutionize schizophrenia treatment

Uptick in early-onset gastrointestinal cancers raises the need for better prevention and diagnosis

Fighting cancer with nanoparticles

Chronic loneliness associated with higher stroke risk independent of depressive symptoms or social isolation

AI breakthrough: Speech analysis predicts Alzheimer's progression with 78.5% accuracy

Diabetes decoded: How your gut microbiome influences disease risk

New-onset anxiety in adults aged 50+ doubles risk of developing Parkinson's disease

Study shows high rates of unrecognized heart valve disease in healthy seniors

Study identifies key neurons controlling threat response and escape in mice

Cell division's hidden safety mechanism may influence cancer growth

New electrospinning innovations transform wearable and implantable medical devices

Amorphous calcium phosphate drives aortic valve stiffening

A unifying marker streamlines macrophage research across age and sex

Researchers identify key players in abnormal bone differentiation

Early diagnosis key in combating the deadly effects of AL amyloidosis

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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