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Study reveals effective combination therapy to slow cognitive decline in older adults

An important new study led by the Centre for Addiction and Mental Health (CAMH), and with partnership across several Toronto Dementia Research Alliance (TDRA) sites-; Baycrest, Sunnybrook Health Science Centre, Unity Health Toronto, and University Health Network-; has demonstrated that a combination therapy can slow cognitive decline in older adults at risk for dementia.

1 Nov 2024

Transcranial ultrasound stimulation: A new frontier in noninvasive brain therapy

Transcranial ultrasound stimulation combines accuracy and reversibility, paving the way for innovative treatments of neurological and psychiatric disorders.

1 Nov 2024

Adolescents' genetic risks tied to psychotic symptoms

Researchers examine the relationships between neuropsychiatric and cognitive polygenic scores, attention-related phenotypes, and psychosis symptoms.

1 Nov 2024

Non-Hispanic Black children and low-income youth disadvantaged in concussion care

Researchers from Children's Hospital of Philadelphia (CHOP) found that non-Hispanic Black children and those with public insurance and lower Child Opportunity Index (COI) scores were much more likely to seek care for concussions in the emergency department than in primary care or specialty care settings.

1 Nov 2024

3D tumor mapping reveals new insights into cancer biology and treatment

A new analysis led by researchers at Washington University School of Medicine in St. Louis has revealed detailed 3D maps of the internal structures of multiple tumor types. These cancer atlases reveal how different tumor cells -; and the cells of a tumor's surrounding environment -; are organized, in 3D, and how that organization changes when a tumor spreads to other organs.

1 Nov 2024

New therapeutic target overcomes ovarian cancer immunotherapy resistance

Researchers at the Icahn School of Medicine at Mount Sinai have discovered a way that ovarian cancer tumors manipulate their environment to resist immunotherapy and identified a drug target that could overcome that resistance.

1 Nov 2024

Weill Cornell Medicine professor receives major grant for pediatric pain management study

Dr. Chani Traube, the Gerald M. Loughlin, MD Professor of Pediatrics at Weill Cornell Medicine, has been awarded a $3.4 million grant, with the possibility of extending to a total of $17 million over five years, from the National Institutes of Health, for a large-scale clinical trial called Optimizing Pain Treatment in Children on Mechanical ventilation (OPTICOM).

1 Nov 2024

Research reveals role of IGFBP3 in human lung development

Researchers of the University of Barcelona and the August Pi y Sunyer Biomedical Research Institute (IDIBAPS) have shown that the IGFBP3 protein plays a relevant role in human lung development.

1 Nov 2024

Mindfulness meditation outperforms placebo in reducing pain

Mindfulness meditation, which has been used for centuries for pain management in various cultures, has long been speculated to work by activating processes supporting the placebo response.

1 Nov 2024

Telephone therapy reduces mental health symptoms in refugee children

Telephone therapy delivered to refugee children results in a significant drop in mental health symptoms and a far higher completion rate of treatment compared with in-person therapy, according to a first-of-its-kind led by the University of Surrey.

1 Nov 2024

Researchers develop novel oxygen-independent therapy for cancer

Tumors often contain areas of oxygen-deficient tissue that frequently withstand conventional therapies. This is because the drugs applied in tumors require oxygen to be effective. An international research team has developed a novel mechanism of action that works without oxygen: polymeric incorporated nanocatalysts target the tumor tissue selectively and switch off the glutathione that the cells need to survive.

1 Nov 2024

Innovative approach boosts spatial memory using VR and brain stimulation

EPFL researchers have combined virtual reality, non-invasive brain stimulation and advanced brain imaging techniques to improve spatial navigation in healthy participants. The study is a first step in addressing dementia in an aging population without medication or surgery.

1 Nov 2024

New pipeline analyzes drug responses in primary tumors

In a major leap toward more effective cancer treatments, researchers at the University of Oulu have developed an innovative pipeline designed to directly analyze drug responses in primary patient tumor samples.

1 Nov 2024

Targeting necroptosis could halt nerve cell loss in Alzheimer's

Alzheimer's disease is characterized by a progressive loss of nerve cells leading to a decline in memory and cognition.

1 Nov 2024

Brain actively engages with immune system to maintain health

The brain constantly engages in dialogue with the body's immune system. Such communication appears aimed at ensuring a delicate balance between defending against injury and infection and guarding healthy tissue.

1 Nov 2024

Study reveals the role of eye movements in Parkinson's disease

Rapid side-to-side eye movements can help stabilize posture, avoid falls and maintain balance for people with Parkinson's disease, just as they can for healthy people. This seemingly counterintuitive conclusion was reached by researchers at São Paulo State University (UNESP) in Brazil and the University of Lille in France in a study supported by FAPESP. An article on the study is published in the journal Biomechanics.

1 Nov 2024