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Family-based approach to lifestyle interventions can reduce weight and cardiovascular risks

The PROgramme of Lifestyle Intervention in Families for Cardiovascular risk reduction (PROLIFIC) Study, conducted in India, aimed to assess whether a family-based approach to lifestyle interventions could improve weight management and obesity-related health outcomes among individuals with a family history of premature coronary heart disease.

24 Mar 2025

Long-term inhaled corticosteroids linked to increased health risks in COPD patients

Inhaled corticosteroids (ICS) are commonly prescribed for chronic obstructive pulmonary disease (COPD), but not recommended as first-line treatment unless patients have asthma/COPD overlap or frequent exacerbations.

24 Mar 2025

Scientists uncover role of m6A in prostate cancer progression

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the progression of prostate cancer, including driving some of its most dangerous forms of the disease.

24 Mar 2025

Researchers develop TIM-3 decoy to enhance CAR-T therapy effectiveness for B-ALL tumors

B-cell Acute Lymphoblastic Leukemia (B-ALL) is a life-threatening and highly aggressive form of blood cancer. It is the most common childhood cancer, making up 35% of pediatric cancer cases, but it can affect people of any age.

24 Mar 2025

New insights into how sleep reorganizes neuronal activity for better memory

Why is sleep so important for learning and memory? Neuroscientists from the Csicsvari group at the Institute of Science and Technology Austria (ISTA) provided new insight into this essential function by monitoring neuronal activity in rat brains for up to 20 hours of sleep following spatial learning.

24 Mar 2025

Novel long-acting contraceptive implant can be delivered through tiny needles

Mass General Brigham and MIT investigators have developed a long-acting contraceptive implant that can be delivered through tiny needles to minimize patient discomfort and increase the likelihood of medication use.

24 Mar 2025

Ketogenic diet reverses obesity-linked biological aging by over 6 years

Obesity speeds up biological aging at the molecular level, but this study finds that a very-low-calorie ketogenic diet (VLCKD) can significantly reverse this effect.

24 Mar 2025

UZH researchers develop decoy molecules to restore immune defense

An immune system defect makes affected individuals vulnerable to severe viral diseases such as influenza or COVID-19. It is caused by the body's own antibodies, which inhibit important defense proteins known as type I interferons.

24 Mar 2025

New MIT method promises less painful drug injections with tiny crystals

MIT engineers have devised a new way to deliver certain drugs in higher doses with less pain, by injecting them as a suspension of tiny crystals.

24 Mar 2025

A pecan a day keeps bad cholesterol away

Daily consumption of 57g of pecans for 12 weeks improved cholesterol profiles and diet quality in adults at risk of cardiometabolic disease, without affecting vascular health. Replacing typical snacks with pecans led to higher intake of healthy fats and fiber, and reduced carbohydrate consumption.

24 Mar 2025

Red wine lowers bad cholesterol but doesn’t improve overall heart health

Moderate red wine consumption is linked to a small but significant reduction in LDL cholesterol, according to a systematic review and meta-analysis of 33 studies. However, the study found no consistent effects on HDL, triglycerides, total cholesterol, or fibrinogen.

24 Mar 2025

What do Blue Zone diets have in common? Polyphenols that may slow aging

Scientists reviewed how polyphenol-rich diets in Blue Zones may help people live longer, healthier lives by targeting biological hallmarks of aging. They call for more research to measure polyphenol intake and test its effects on human longevity.

24 Mar 2025

Fish oil supplements beat oily fish at reducing harmful blood vesicles

Fish oil supplements, delivering higher EPA doses, significantly reduced the number and procoagulant activity of extracellular vesicles—unlike oily fish. This suggests EPA, not DHA, may drive cardiovascular benefits linked to EV function.

24 Mar 2025

Skipping exercise? Just sitting less may still improve your metabolic health

Older adults who limit their sedentary time have lower metabolic syndrome risk, regardless of how active they are or how healthy they eat. Even light movement can support better metabolic health when replacing prolonged sitting.

24 Mar 2025

Waist circumference identified as a stronger cancer risk marker in men

Body size and excess weight, conventionally assessed using body mass index (BMI), are well-established risk factors for many types of cancer. However, new research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of the National Cancer Institute shows that waist circumference (WC) is a stronger risk marker than BMI for developing obesity-related cancers in men, but not women.

24 Mar 2025

Simple urine test may spare kidney cancer patients from invasive scans

A simple urine test could accurately show the recurrence of kidney cancer at an early stage, potentially sparing patients invasive scans and enabling faster access to treatment, new research has shown.

24 Mar 2025

Epstein-Barr virus triggers inflammatory cell death in ulcerative colitis

Ulcerative colitis (UC) is a chronic, relapsing disease that causes painful inflammation and ulcers in the colon.

24 Mar 2025

Researchers develop tool to enhance NK cells against cancer

A team of researchers from the Hospital del Mar Research Institute, the Universitat Autònoma de Barcelona and the Pompeu Fabra University has developed a new tool that allows modifying these NK cells to make them immune to the tumor’s defense mechanism.

24 Mar 2025

Depression prevention program shows unequal effectiveness among youth

A depression prevention program that has helped white youth wasn't effective for Black youth, raising concerns about the need for more research to help racially diverse groups, according to new research published by the American Psychological Association.

24 Mar 2025

Lifelong weight patterns linked to kidney cancer risk

Excess weight in mid-life is a known risk factor for kidney cancer, but new research indicates that weight patterns throughout life may also affect an individual's likelihood of developing this malignancy.

24 Mar 2025