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Uninterrupted use of new anticoagulant reduces major bleeding events during atrial fibrillation ablation

Uninterrupted treatment with dabigatran, a non-vitamin K antagonist oral anticoagulant (NOACs), before, during and after ablation to treat atrial fibrillation significantly reduced the incidence of major bleeding events compared with uninterrupted use of the more established anticoagulant warfarin, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Closing left atrial appendage linked to reduction in stroke risk for AFib patients

For patients with atrial fibrillation (AFib), a common heart rhythm disorder, closing the area of the heart known as the left atrial appendage as an add-on procedure during cardiac surgery was associated with a 40 percent reduction in the risk of thromboembolism (a condition when a blood clot forms and blocks an artery, which can cause a stroke or other complications) according to an observational study presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Study reveals link between endovascular procedures and microbleeding in the brain

Small leakages from blood vessels in the brain, known as microbleeds, increase with age and are associated with cognitive decline. Of 84 older patients undergoing transcatheter aortic valve replacement (TAVR), nearly a quarter developed new microbleeds after their procedure, according to results of a single-center study presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

CT scans reveal subclinical leaflet thrombosis in patients undergoing aortic valve replacement

About 12 percent of patients undergoing aortic valve replacement developed non-symptomatic blood clots around the valve leaflets (known as subclinical leaflet thrombosis) that reduced the motion of the valves, according to an observational study presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Blood test can identify patients with heart injury after non-cardiac surgery

A blood test for a protein called high-sensitivity troponin T, which is released into the bloodstream when injury to the heart occurs, can identify patients with heart damage after non-cardiac surgery whose lives could potentially be saved with timely treatment, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.

20 Mar 2017

Treating clogged arteries after heart attack improves outcomes, helps avoid subsequent procedures

Patients experiencing a major heart attack often have more than one clogged artery, but under current guidelines doctors typically only clear the blockage responsible for the heart attack.

20 Mar 2017

New iFR technique for assessing clogged arteries reduces discomfort and adverse events

For patients experiencing angina (chest pain) or a heart attack, a new tool called instantaneous wave-free ratio (iFR) was equivalent to the currently-preferred tool, fractional flow reserve (FFR), in terms of incidence of major adverse events according to two studies presented at the American College of Cardiology's 66th Annual Scientific Session. The studies also showed iFR resulted in markedly less patient discomfort and reduced procedure-related adverse events compared to FFR.

20 Mar 2017

Online behavioral intervention reduces systolic blood pressure by 10 mmHg, study finds

In the first randomized, double-blinded trial of an online behavioral intervention for high blood pressure, participants in web-based lifestyle counseling reduced their systolic blood pressure (the higher number in a blood-pressure reading) by 10 mmHg, compared with a 6 mmHg reduction for those taking part in a web-based control intervention, a statistically significant difference.

20 Mar 2017

Reirradiation using proton therapy offers new hope for patients with recurrent lung cancer

A new study offers hope for patients with recurrent lung cancer, who historically have been considered ineligible for curative treatment. In the largest analysis to date of reirradiation using intensity-modulated proton therapy for lung and other thoracic tumors, more than three-fourths of patients were free from local recurrence at one year following retreatment, and fewer than one in ten patients experienced severe side effects.

17 Mar 2017

Research shows SBRT as viable curative option for older lung cancer patients

Patients in their 80s and 90s who have early stage lung cancer but cannot undergo an operation can be treated safely and effectively with stereotactic body radiation therapy (SBRT), according to research presented today at the 2017 Multidisciplinary Thoracic Cancers Symposium.

17 Mar 2017

Study reveals prevalence of racial disparities in treatment, outcomes of early stage NSCLC patients

Analysis of the largest American cancer database indicates that racial disparities persist in the treatment and outcomes of patients diagnosed with stage I non-small cell lung cancer (NSCLC).

17 Mar 2017

Genetic mutations underlying treatment resistance in NSCLC more dynamic than previously thought

The genetic mutations underlying treatment resistance in non-small cell lung cancer (NSCLC) are more complex and dynamic than previously thought.

17 Mar 2017

Combination approach holds potential for treating lung cancer patients

An emerging approach for cancer treatment seeks to combine radiation therapy with immune checkpoint inhibitors to more effectively control tumors in the chest with an acceptable risk of severe treatment-related side effects.

17 Mar 2017

Biomarker blood test detects recurrences of lung cancer before conventional imaging methods

Results from a prospective clinical trial showed that a blood test looking at specific biomarkers was able to detect recurrences of lung cancer an average of six months before conventional imaging methods found evidence of recurrence.

17 Mar 2017

Increased palliative care consultation for advanced cancer patients leads to better outcomes

A recent study demonstrated that increased palliative care consultations for patients with advanced cancers is associated with substantial impact on 30-day readmission, administration of chemotherapy following discharge, hospice referral, and use of support services following discharge.

17 Mar 2017

Penn study reveals new patterns of coordinated development in the brain during adolescence

Adolescence marks not only the period of physical maturation bridging childhood and adulthood, but also a crucial period for remodeling of the human brain.

17 Mar 2017

Low-risk atrial fibrillation patients fare better without antithrombotic therapy, study finds

Findings from a large, community-based study show that antithrombotic therapy doesn't decrease low-risk atrial fibrillation patients' risk of suffering a stroke within five years. In fact, researchers found that low-risk patients fared better without any antithrombotic therapy.

17 Mar 2017

URI researchers awarded federal funding to improve environmental, behavioral health

Pilot Projects involving two researchers at the University of Rhode Island have been awarded federal funding through Advance Clinical and Translational Research, a statewide effort to support clinical research that can be translated into approaches and policies that improve the health of Rhode Islanders.

17 Mar 2017

Research findings point to new strategies for tapping into plant energy to produce biofuels, biomaterials

Even plants have to live on an energy budget. While they're known for converting solar energy into chemical energy in the form of sugars, plants have sophisticated biochemical mechanisms for regulating how they spend that energy. Making oils costs a lot.

17 Mar 2017

Intensity modulated proton therapy shows early promise for treatment of recurrent lung cancer

An advanced form of image-guided radiation therapy, known as intensity modulated proton therapy, has shown early promise for the treatment of recurrent lung cancer, according to new research from The University of Texas MD Anderson Cancer Center.

17 Mar 2017

Medical Research News

Uninterrupted use of new anticoagulant reduces major bleeding events during atrial fibrillation ablation

Closing left atrial appendage linked to reduction in stroke risk for AFib patients

Study reveals link between endovascular procedures and microbleeding in the brain

CT scans reveal subclinical leaflet thrombosis in patients undergoing aortic valve replacement

Blood test can identify patients with heart injury after non-cardiac surgery

Treating clogged arteries after heart attack improves outcomes, helps avoid subsequent procedures

New iFR technique for assessing clogged arteries reduces discomfort and adverse events

Online behavioral intervention reduces systolic blood pressure by 10 mmHg, study finds

Reirradiation using proton therapy offers new hope for patients with recurrent lung cancer

Research shows SBRT as viable curative option for older lung cancer patients

Study reveals prevalence of racial disparities in treatment, outcomes of early stage NSCLC patients

Genetic mutations underlying treatment resistance in NSCLC more dynamic than previously thought

Combination approach holds potential for treating lung cancer patients

Biomarker blood test detects recurrences of lung cancer before conventional imaging methods

Increased palliative care consultation for advanced cancer patients leads to better outcomes

Penn study reveals new patterns of coordinated development in the brain during adolescence

Low-risk atrial fibrillation patients fare better without antithrombotic therapy, study finds

URI researchers awarded federal funding to improve environmental, behavioral health

Research findings point to new strategies for tapping into plant energy to produce biofuels, biomaterials

Intensity modulated proton therapy shows early promise for treatment of recurrent lung cancer

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