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Researchers shed new light on molecular pump that ejects anticancer agents

Sometimes cells resist medication by spitting it back out. Cancer cells, in particular, have a reputation for defiantly expelling the chemotherapy drugs meant to kill them. Researchers at The Rockefeller University have shed new light on a molecular pump that makes this possible, by determining its three-dimensional structure, down to the level of atoms.

25 Feb 2017

Fred Hutch scientists make important step in identifying specific T cells to fight against cancer

A new discovery by researchers at the Fred Hutchinson Cancer Research Center in Seattle makes an important step in identifying which specific T cells within the diverse army of a person's immune system are best suited to fight cancer.

25 Feb 2017

Deep brain stimulation may help improve mental, physical health in patients with anorexia nervosa

Deep brain stimulation might alter the brain circuits that drive anorexia nervosa symptoms and help improve patients’ mental and physical health, according to a small study published in The Lancet Psychiatry.

25 Feb 2017

New study confirms benefits of Medtronic’s Solitaire stent retriever for stroke patients in real-world setting

Data presented today on Medtronic’s Solitaire stent retriever at the International Stroke Conference in Houston demonstrate that the results from the four pivotal randomized controlled trials – SOLITAIRE FR With the Intention For Thrombectomy as PRIMary Endovascular Treatment for Acute Ischemic Stroke, Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke, EXtending the Time for Thrombolysis in Emergency Neurological Deficits - Intra-Arterial and Endovascular Revascularization With Solitaire Device Versus Best Medical Therapy in Anterior Circulation Stroke Within 8 Hours – can be replicated in U.S. centers, in a pragmatic, real-world setting reconfirming the benefits of mechanical thrombectomy in patients suffering acute ischemic stroke (AIS).

25 Feb 2017

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Donepezil, a medication that is approved to treat people with Alzheimer's disease, should not be prescribed for people with mild cognitive impairment without a genetic test.

24 Feb 2017

Scientists unravel mechanism of rare, early phenomenon that can affect human development

The genetic material of an organism encodes the instructions that guide its development. These codes are not written in stone; they can change or mutate any time during the life of the organism.

24 Feb 2017

MGH researchers discover regulators of gene expression programs in medulloblastoma

Massachusetts General Hospital researchers have identified a mechanism that controls the expression of genes regulating the growth of the most aggressive form of medulloblastoma, the most common pediatric brain tumor. In their report published online in Cancer Discovery, the team also identifies potential targets for future treatments.

24 Feb 2017

Adolescent female offspring could be rescued from negative effects of poor maternal diet during pregnancy

Here's some good news if you are female: Research published online in The FASEB Journal, shows that in mice, what is eaten during adolescence or childhood development may alter long-term behavior and learning, and can even "rescue" females from the negative effects on behavior resulting from a poor maternal diet during pregnancy.

24 Feb 2017

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

An in-depth computational analysis of genetic variants implicated in both schizophrenia and rheumatoid arthritis by researchers at the University of Pittsburgh points to eight genes that may explain why susceptibility to one of the disorders could place individuals at lower risk for the other, according to the results of a study published today in the journal npj Schizophrenia.

24 Feb 2017

Dietary prebiotics can improve sleep after stress exposure, study suggests

In recent years, reams of research papers have shed light on the health benefits of probiotics, the "good bacteria" found in fermented foods and dietary supplements.

24 Feb 2017

Princeton-Intel collaboration builds new software to decode brain scans

Early this year, about 30 neuroscientists and computer programmers got together to improve their ability to read the human mind.

24 Feb 2017

Researchers discover promising target for treatment of leishmaniasis

Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.

24 Feb 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

New study finds huge problem of multi-drug resistant infections among children

In a new, first-of-its-kind study, researchers from Case Western Reserve University School of Medicine have found a 700-percent surge in infections caused by bacteria from the Enterobacteriaceae family resistant to multiple kinds of antibiotics among children in the US. These antibiotic resistant infections are in turn linked to longer hospital stays and potentially greater risk of death.

24 Feb 2017

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Successful results of a University of Liverpool-led trial that utilised nanotechnology to improve drug therapies for HIV patients has been presented at the Conference on Retroviruses and Opportunistic Infections in Seattle, a leading annual conference of HIV research, clinical practice and progress.

24 Feb 2017

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Scientists at The Wistar Institute and Inovio Pharmaceuticals, Inc. have devised a novel DNA vaccine approach through molecular design to improve the immune responses elicited against one of the most important cancer antigen targets. Study results were published in the journal Molecular Therapy.

24 Feb 2017

Online health tools with good, controlled communication could promote healthier lifestyles

Just like real doctors and nurses, online health tools with good -- but controlled -- communication skills can promote healthier lifestyles, according to researchers. However, if their tone is conversational, these tools may lull users into a false sense of comfort, they add.

24 Feb 2017

High levels of physical activity affects pain perceptions in older adults, study finds

Older adults with higher levels of physical activity have pain modulation patterns that might help lower their risk of developing chronic pain, reports a study in PAIN, the official publication of the International Association for the Study of Pain. The journal is published by Wolters Kluwer.

24 Feb 2017

New investigational drug may help combat antibiotic-resistant global health threat

The deadly fungus, Candida auris, which has been found in hospitals, is resistant to entire classes of antimicrobial drugs, limiting treatment options for those infected.

24 Feb 2017

Study reveals inaccuracy of exercise test that could lead to unnecessary open heart surgeries

An approved international test to check whether people need open heart surgery could be sending twice as many people under the knife unnecessarily, at a cost of nearly £75m, research by the University of Leicester has suggested.

24 Feb 2017

Medical Research News

Researchers shed new light on molecular pump that ejects anticancer agents

Fred Hutch scientists make important step in identifying specific T cells to fight against cancer

Deep brain stimulation may help improve mental, physical health in patients with anorexia nervosa

New study confirms benefits of Medtronic’s Solitaire stent retriever for stroke patients in real-world setting

Alzheimer's drug prescribed off-label could accelerate cognitive decline for some patients

Scientists unravel mechanism of rare, early phenomenon that can affect human development

MGH researchers discover regulators of gene expression programs in medulloblastoma

Adolescent female offspring could be rescued from negative effects of poor maternal diet during pregnancy

Pitt study sheds light on shared roots of schizophrenia and rheumatoid arthritis

Dietary prebiotics can improve sleep after stress exposure, study suggests

Princeton-Intel collaboration builds new software to decode brain scans

Researchers discover promising target for treatment of leishmaniasis

Novel antiviral drug can protect transplant patients against CMV infections

New study finds huge problem of multi-drug resistant infections among children

New trial examines use of nanotechnology to improve delivery of drugs to HIV patients

Scientists devise novel DNA vaccine approach against important cancer antigen targets

Online health tools with good, controlled communication could promote healthier lifestyles

High levels of physical activity affects pain perceptions in older adults, study finds

New investigational drug may help combat antibiotic-resistant global health threat

Study reveals inaccuracy of exercise test that could lead to unnecessary open heart surgeries

In the Thymus We Trust: ProTcell Therapy & the Future of Allogeneic Immunotherapy

Making Complex Cell Culture Easy and Efficient with AI

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

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