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Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Each day, more than 1,600 people die from cancer in the US, and 450 in the UK, mostly because the disease has spread beyond a stage when surgery is an effective cure and has become resistant to therapy. Despite decades of research, understanding why cancer cells become invasive has remained shrouded in mystery.

17 Jan 2017

Biomarker could help identify heart failure patients suitable for cardiac recovery therapies

Investigators at the University of Utah have identified distinct differences in the hearts of advanced heart failure patients who have defied the odds and showed signs of recovery from the disease. Published online in the journal Circulation, the new findings could help clinicians identify the best candidates for cardiac recovery therapies.

17 Jan 2017

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Massachusetts General Hospital investigators have identified a protein that may play an essential role in maintaining a population of tumor-initiating cells (TICs) -- treatment-resistant cells responsible for cancer recurrence and metastasis -- in breast cancer, as well as a compound that appears to reduce the molecule's ability to protect TICs from the effects of chemotherapy.

17 Jan 2017

Researchers find explanation for link between persistent infection and long-term immunity

Many infectious diseases are one and done; people get sick once and then they are protected from another bout of the same illness.

17 Jan 2017

Yale researchers discover how tick-borne bacteria cause infection

Before infecting humans, tick-borne bacteria or viruses first have to get past a tick's defenses to colonize it.

17 Jan 2017

Drug-resistant deadly bacteria more widespread than previously thought, study finds

A family of highly drug-resistant and potentially deadly bacteria may be spreading more widely--and more stealthily -- than previously thought, according to a new study from Harvard T.H. Chan School of Public Health and the Broad Institute of MIT and Harvard.

17 Jan 2017

Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

A naturally-occurring compound has been found to block a molecular process thought to underlie Parkinson's Disease, and to suppress its toxic products, scientists have reported.

17 Jan 2017

Implantable cardioverter-defibrillator improves survival rate in older patients, study finds

Of patients over age 65 who received an implantable cardioverter-defibrillator (ICD) after surviving sudden cardiac arrest or a near-fatal arrhythmia, almost 80 percent survived two years--a higher rate than found in past trials performed to demonstrate the efficacy of the devices in this situation, according to a study today in the Journal of the American College of Cardiology.

17 Jan 2017

Knowledge bank approach could help find best treatment option for AML patients

An international collaboration led by clinical researchers at the Wellcome Trust Sanger Institute has shown proof-of-concept that truly personalised therapy will be possible in the future for people with cancer.

17 Jan 2017

Every meal triggers short-term inflammatory responses in healthy individuals

When we eat, we do not just take in nutrients - we also consume a significant quantity of bacteria. The body is faced with the challenge of simultaneously distributing the ingested glucose and fighting these bacteria.

17 Jan 2017

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Metastatic pancreatic cancer -- cancer that has spread from the pancreas to other tissues and is responsible for most patient deaths -- changes its metabolism and is "reprogrammed" for optimal malignancy, according to new findings reported Jan. 16 in Nature Genetics.

16 Jan 2017

Cattle-based vector control efforts may help eradicate malaria in India

The goal of eliminating malaria in countries like India could be more achievable if mosquito-control efforts take into account the relationship between mosquitoes and cattle, according to an international team of researchers.

16 Jan 2017

Functional deficits caused by mini-strokes can last longer than previously thought

Evidence overwhelmingly supports a link between cognitive decline and cerebrovascular diseases such as atherosclerosis, arteriolosclerosis, and cerebral amyloid angiopathy. Not only do individuals with cerebrovascular diseases have a much higher incidence of cortical microinfarcts (mini-strokes), but post-mortem histological and in vivo radiological studies also find that the burden of microinfarcts is significantly greater among people with vascular cognitive impairment and dementia (VCID) than in age-matched, non-demented individuals.

16 Jan 2017

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Using a combination of infrared spectroscopy and computer simulation, researchers at Ruhr-Universität Bochum have gained new insights into the workings of protein switches.

16 Jan 2017

Researchers discover underlying cause for formation of granulomas

Granulomas are tissue nodules of immune cells that occur in diseases such as tuberculosis and sarcoidosis and can damage many organs.

16 Jan 2017

Non-invasive technology from EarlySense allows people to accurately monitor their sleep at home

EarlySense, the market leader in contact-free continuous monitoring solutions, announced today new research that confirms high accuracy of its home consumer sensor when compared to polysomnography (PSG), the testing process used in clinics around the world to detect sleeping disorders.

16 Jan 2017

New antibody design may pave way for treating diseases affecting the brain

Immunotherapy has proven to be effective against many serious diseases. But to treat diseases in the brain, the antibodies must first get past the obstacle of the blood-brain barrier.

16 Jan 2017

Prevalence of atrial fibrillation in haemodialysis patients higher than previously thought

Atrial fibrillation, which is the most common cardiac arrhythmia, is an important risk factor for strokes.

16 Jan 2017

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Nanoparticles from combustion engines can activate viruses that are dormant in lung tissue cells. This is the result of a study by researchers of Helmholtz Zentrum München, a partner in the German Center for Lung Research, which has now been published in the journal 'Particle and Fibre Toxicology'.

16 Jan 2017

Antivirals that block influenza can also inhibit Zika virus infection, study shows

Researchers from the University of Helsinki have shown that three anti-influenza compounds effectively inhibit Zika virus infection in human cells.

16 Jan 2017

Medical Research News

Ludwig study uncovers ancient cellular response that underlies spread of aggressive skin cancer

Biomarker could help identify heart failure patients suitable for cardiac recovery therapies

MGH researchers identify protein that may protect tumor-initiating cells in breast cancer

Researchers find explanation for link between persistent infection and long-term immunity

Yale researchers discover how tick-borne bacteria cause infection

Drug-resistant deadly bacteria more widespread than previously thought, study finds

Naturally-occurring compound can inhibit early formation of toxins linked to Parkinson's Disease

Implantable cardioverter-defibrillator improves survival rate in older patients, study finds

Knowledge bank approach could help find best treatment option for AML patients

Every meal triggers short-term inflammatory responses in healthy individuals

Researchers explore how metastatic pancreatic cancer gets ‘reprogrammed’ for optimal malignancy

Cattle-based vector control efforts may help eradicate malaria in India

Functional deficits caused by mini-strokes can last longer than previously thought

Spectroscopy and computer help RUB scientists gain new insights into workings of protein switches

Researchers discover underlying cause for formation of granulomas

Non-invasive technology from EarlySense allows people to accurately monitor their sleep at home

New antibody design may pave way for treating diseases affecting the brain

Prevalence of atrial fibrillation in haemodialysis patients higher than previously thought

Nanoparticle exposure can trigger dormant viruses in lung tissue cells

Antivirals that block influenza can also inhibit Zika virus infection, study shows

Making Complex Cell Culture Easy and Efficient with AI

This International Women’s Day, Meet the Scientist Changing Women’s Healthcare

Microphysiological systems in drug discovery

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