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Penn study provides more insights into cardiovascular side effects of breast cancer drug

A receptor protein that is the target of the breast cancer drug trastuzumab (Herceptin) is needed for proper heart blood-vessel development, reported researchers from the Perelman School of Medicine at the University of Pennsylvania.

14 Jul 2016

Gender matching may be beneficial to reduce risk of corneal transplant rejection and failure

A study of patients undergoing corneal transplants indicates that subtle differences between men and women may lead to poorer outcomes for a woman who has received a cornea from a male donor.

14 Jul 2016

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Older adults with chronic obstructive pulmonary disease who start using opioids have a more than two-fold higher risk of dying from a respiratory-related complication compared to non-opioid users, St. Michael's Hospital researchers have found.

14 Jul 2016

Preschoolers with early bedtime routines less likely to become obese teenagers

Preschoolers who are regularly tucked into bed by 8 p.m. are far less likely to become obese teenagers than young children who go to sleep later in the evening, new research has found.

14 Jul 2016

Losing weight can lower levels of some proteins linked to tumor growth

Overweight and obese women who lost weight through diet and exercise lowered the levels of certain proteins in their blood that play a role in angiogenesis, the process of blood vessel growth that can promote the growth and survival of cancer cells

14 Jul 2016

Study examines interventions designed to reduce low-value care

The Institute of Medicine estimates that up to 30% of care provided in the United States is unnecessary and provides little value to patients given the cost and available alternatives.

14 Jul 2016

Genes linked to Alzheimer's disease may show effects on the brain from childhood

A gene associated with Alzheimer's disease and recovery after brain injury may show its effects on the brain and thinking skills as early as childhood, according to a study published in the July 13, 2016, online issue of Neurology, the medical journal of the American Academy of Neurology.

14 Jul 2016

Moffitt researchers receive grant to examine prostate cancer metastasis

Moffitt researchers David Basanta, PhD, and Conor Lynch, PhD, have been awarded a U01 grant to investigate prostate cancer metastasis.

14 Jul 2016

Researcher aims to make early detection of melanoma faster, cheaper without need for biopsy

Melanoma is a form of skin cancer that becomes dangerous when it spreads, but is treatable in its early stages. Doctors diagnose melanoma by cutting away a piece of a suspicious skin lesion -- a procedure known as a biopsy -- and testing it for malignant cells.

14 Jul 2016

Study finds ethnic differences in circadian blood pressure variation

Differences in circadian blood pressure variation due to a combination of genetic and cultural factors may contribute to ethnic differences in cardiovascular morbidity, according to new research from Binghamton University, State University of New York.

14 Jul 2016

AAPS Foundation announces winner of 2016 New Investigator Grant

The AAPS Foundation is pleased to announce the 2016 New Investigator Grant recipient, Yizhou Dong, Ph.D of the Ohio State University, for his research entitled "Development of nonviral gene-engineering delivery systems".

14 Jul 2016

New treatment approach may benefit relapsed post-transplant blood cancer patients

For many patients with advanced blood cancers, a stem-cell transplant can drive the disease into remission. However, about one-third of these patients experience a relapse and face a very poor prognosis.

13 Jul 2016

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

The Wistar Institute is pleased to announce that the National Institutes of Health has awarded a nearly $23 million Martin Delaney Collaboratories for HIV Cure Research grant to the BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy, a consortium of top HIV researchers led by co-principal investigators Luis J. Montaner, D.V.M., D.Phil., director of the HIV-1 Immunopathogenesis Laboratory at The Wistar Institute Vaccine Center, and James L. Riley, Ph.D., research associate professor at the Perelman School of Medicine at the University of Pennsylvania.

13 Jul 2016

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

UCLA researchers have for the first time identified mechanisms that determine how advanced melanoma can become resistant to immune checkpoint inhibitors, a discovery that could lead to the development of new and improved treatments for the deadliest type of skin cancer.

13 Jul 2016

Regular drug use may hamper moral decision making

Regular cocaine and methamphetamine users can have difficulty choosing between right and wrong, perhaps because the specific parts of their brains used for moral processing and evaluating emotions are damaged by their prolonged drug habits.

13 Jul 2016

Study finds high prevalence of tinnitus among adolescents

Teenagers are increasingly experiencing tinnitus, often a symptom of hearing loss, as a result of using ear buds to listen to music for long periods every day, as well as frequenting very noisy places like nightclubs, discos and rock concerts, according to a study performed in Brazil.

13 Jul 2016

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Researchers have developed a diagnostic model that is highly predictive of nonalcoholic fatty liver disease (NAFLD).

13 Jul 2016

Food nudging could contribute to healthy eating

Is it possible to change our behaviour when it comes to food choices only by presenting the food to the guests in a canteen in a different order, or by making it more difficult to reach the less healthy food? Yes, a review of existing research in this area concludes.

13 Jul 2016

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

A Houston Methodist research team received a nearly $4 million grant to test a transcutaneously refillable implant that administers pre-exposure prophylaxis drugs to subjects at risk of HIV-exposure.

13 Jul 2016

New, minimally invasive procedure may be effective for patients with FED

A new, minimally invasive procedure appears to be effective for many patients with Fuchs endothelial dystrophy (FED), a common eye disease, without the potential side effects and cost of the current standard of care, a cornea transplant.

13 Jul 2016

Medical Research News

Penn study provides more insights into cardiovascular side effects of breast cancer drug

Gender matching may be beneficial to reduce risk of corneal transplant rejection and failure

New opioid use among older adults with COPD linked to increased risk for respiratory-related death

Preschoolers with early bedtime routines less likely to become obese teenagers

Losing weight can lower levels of some proteins linked to tumor growth

Study examines interventions designed to reduce low-value care

Genes linked to Alzheimer's disease may show effects on the brain from childhood

Moffitt researchers receive grant to examine prostate cancer metastasis

Researcher aims to make early detection of melanoma faster, cheaper without need for biopsy

Study finds ethnic differences in circadian blood pressure variation

AAPS Foundation announces winner of 2016 New Investigator Grant

New treatment approach may benefit relapsed post-transplant blood cancer patients

The Wistar Institute and partners receive HIV cure research grant to test novel immunotherapies

UCLA scientists identify mechanisms of tumor resistance to immunotherapy in advanced melanoma

Regular drug use may hamper moral decision making

Study finds high prevalence of tinnitus among adolescents

New diagnostic model may become cheaper and easier alternative to screen for NAFLD

Food nudging could contribute to healthy eating

Researchers receive grant to test transcutaneously refillable implant that delivers HIV-prevention drugs

New, minimally invasive procedure may be effective for patients with FED

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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