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AMPK protein activated during fasting regulates hunger neurons in the brain

Neurons in the brain that control hunger are regulated by AMPK, a protein activated during fasting, report researchers from Tufts University School of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School in Neuron on July 6, 2016.

6 Jul 2016

Vigorous and moderate exercise have same effect on patients with NAFLD

A new study shows a brisk walk is just as good as a jog when it comes to reducing liver fatty content, important news for the more than 3 million people diagnosed each year in the U.S. with nonalcoholic fatty liver disease (NAFLD).

6 Jul 2016

IQWiG study: HBOT shows neither hint of benefit nor of harm in people with diabetic foot

If people with a diabetic foot syndrome (DFS) receive hyperbaric oxygen therapy (HBOT) in addition to conventional treatment, this can promote wound healing. However, the certainty of conclusions of the available study results is restricted.

6 Jul 2016

Existing anti-inflammatory drugs may be effective in treating epilepsy

In epileptic patients, seizures lead to an increased level of inflammation-related proteins called chemokines in the brain, and systemic inflammation likely helps trigger and promote the recurrence of seizures, making inflammation a promising new target for anticonvulsant therapy.

6 Jul 2016

Liraglutide drug lowers blood sugar levels in diabetic patients taking large doses of insulin

When Amy Sweat was 19 years old, while she was in the hospital recovering from surgery, she was diagnosed with Type 2 diabetes. Ms. Sweat was treated for her diabetes, first on oral drugs, then on increasingly larger doses of insulin, but the years went by and she never was able to achieve good blood sugar control.

6 Jul 2016

New coaching program aims to help family caregivers of cancer patients stay healthy

UAB School of Nursing postdoctoral fellow J. Nicholas Dionne-Odom, Ph.D., has received a five-year, $935,000 K99/R00 Pathway to Independence Award from the National Institute of Nursing Research to develop a palliative care health-coaching program for family caregivers of persons with advanced cancer.

6 Jul 2016

Study reveals high healthcare costs for chronic pain patients in Canada

Costs of patients who develop chronic post-surgical pain could range from $2.5 million to $4.1 million a year, in one Ontario hospital alone, according to a study in Pain Management.

6 Jul 2016

Regular marijuana use impacts the brain's natural response to rewards

Most people would get a little 'rush' out of the idea that they're about to win some money.

6 Jul 2016

Added benefit of idelalisib drug not proven for patients with CLL

Already in 2014, the German Institute for Quality and Efficiency in Health Care examined in an early benefit assessment whether idelalisib offers advantages over the appropriate comparator therapy for patients with chronic lymphocytic leukaemia (CLL).

6 Jul 2016

BU researcher receives grant to better understand breast cancer in African-American women

Why do African-American women die at a higher rate and experience more aggressive breast tumors than white women? Researchers from Boston University's Slone Epidemiology Center (SEC) have received funding from the National Cancer Institute to explore this question.

6 Jul 2016

Changes in benign tissue adjacent to prostate tumors could better predict recurrence

Changes in benign tissues next to prostate tumors may provide an early warning for patients at higher risk for biochemical recurrence after a radical prostatectomy, a study by researchers at Case Western Reserve University and Johns Hopkins Medical Institutions shows.

6 Jul 2016

Phase 1 trial to examine efficacy of promising malaria vaccine in Burkina Faso

Malaria is one of the world's deadliest diseases: it infects hundreds of millions of people every year, and kills about half a million, most of them under five years of age.

6 Jul 2016

Whole-genome omics data can improve accuracy of breast cancer survival predictions

Precise predictions of whether a tumor is likely to spread would help clinicians and patients choose the best course of treatment. But current methods fall short of the precision needed.

6 Jul 2016

Conceptual model highlights transmission of chronic pain risk from parent to children

Can an increased risk of chronic pain be transmitted from parents to children? Several factors may contribute, including genetics, effects on early development, social learning, and more according to a report in the journal PAIN, the official publication of the International Association for the Study of Pain.

6 Jul 2016