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Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

A team of physicians and laboratory scientists has taken a key step toward a cure for sickle cell disease, using CRISPR-Cas9 gene editing to fix the mutated gene responsible for the disease in stem cells from the blood of affected patients.

12 Oct 2016

New systems-thinking approach could help improve health of the U.S. population

The United States spends more on health care than any other country in the world, yet the life expectancy of its citizens is significantly shorter when compared to other high-income countries.

12 Oct 2016

Clinical trial finds women with heavy periods can be greatly helped by GP-prescribed treatments

The largest and longest running clinical trial of medical therapies for heavy periods has found that women can be greatly helped by having treatments just from their GP, with most avoiding hospital operations.

12 Oct 2016

Common drug for allergies and asthma could prevent fibrosis, reduce need for liver transplants

A drug commonly used for the prevention of allergies and asthma someday could find new use in preventing liver disease and reducing the need for transplants, according to new research published in the October 2016 edition of the scientific journal Hepatology.

12 Oct 2016

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

A study by a multidisciplinary team of researchers from The Saban Research Institute of Children's Hospital Los Angeles sheds further light on the role of the cytokine TGFβ1 in the growth of neuroblastoma, and suggests the possibility for a small molecule drug/antibody combinatorial therapy to treat this cancer.

12 Oct 2016

Community outreach workers may help increase HBV vaccination rates to cut risk of liver cancer

Liver cancer is more common among Asian Americans in part because they are at high risk of HBV infection.

12 Oct 2016

Researchers identify how amyloid beta linked to Alzheimer's disease could trigger Parkinson's

Alzheimer's and Parkinson's diseases are different neurodegenerative conditions that can sometimes affect the same person, which has led scientists to investigate possible links between the two.

12 Oct 2016

Research findings raise hope for better treatment of diabetic wounds

Diabetics often have to contend with wounds that heal poorly. Researchers at the Max Planck Institute for Biology of Ageing, the CECAD Excellence Cluster and the Institute of Genetics of the University of Cologne have now gained fresh insights into the underlying cellular mechanisms.

12 Oct 2016

Study identifies mechanistic link between maternal obesity and childhood hypertension

Exposure of babies to high levels of the 'fullness' hormone, leptin, in the womb irreversibly activates receptors in the brain that regulate blood pressure, according to a new study by researchers from King's College London, part-funded by the British Heart Foundation.

12 Oct 2016

$Heavy cannabis users have large reduction in bone density, increased risk of bone fractures$

Heavy cannabis users have large reduction in bone density, increased risk of bone fractures

People who regularly smoke large amounts of cannabis have reduced bone density and are more prone to fractures, research has found.

12 Oct 2016

Warm childhood environments linked to secure marriages in late life

Growing up in a warm family environment in childhood is associated with feeling more secure in romantic relationships in one's 80s, according to new research published in Psychological Science, a journal of the Association for Psychological Science.

12 Oct 2016

UVA physicists develop new imaging method with potential for high-resolution medical diagnostics

A unique new imaging method, called "polarized nuclear imaging" - combining powerful aspects of both magnetic resonance imaging and gamma-ray imaging and developed by two physicists in the University of Virginia's departments of Physics and Radiology- has potential for new types of high-resolution medical diagnostics as well as industrial and physics research applications.

12 Oct 2016

Children who experience family, environmental stressors more likely to be diagnosed with ADHD

Children who experience family and environmental stressors, and traumatic experiences, such as poverty, mental illness and exposure to violence, are more likely to be diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD), according to new research by investigators at the Children's Hospital at Montefiore, titled "Associations Between Adverse Childhood Experiences and ADHD Diagnosis and Severity," published in Academic Pediatrics.

12 Oct 2016

NDSU investigator receives $3.7 million grant for bariatric surgery research

Some patients who undergo weight loss surgery to combat obesity don't lose the pounds they expect or they gain weight back. A team of researchers at seven institutions across the United States is working to find out why.

12 Oct 2016

Novel surgical approach can help remove diseased gallbladder through single, small incision

A surgical team at UC San Diego Health has completed the first series of operations with a novel surgical system that can remove a diseased gallbladder through a single incision hidden in the belly button.

12 Oct 2016

Fetal brains use unique amplifier to transmit signals, research shows

Fetal brains use a special amplifier in order to transmit signals, according to research published in the journal eLife by George Washington University's (GW) Matthew Colonnese, Ph.D. and Yasunobu Murata, Ph.D. Early neural connections are sparse, weak, and unreliable.

12 Oct 2016

Excessive televiewing in early childhood can lead to risk of social impairment during adolescence

Results of new study led by Linda Pagani, professor at the University of Montreal's School of Psychoeducation, show that young children who watch too much television are at risk of victimization and social isolation and adopting violent and antisocial behaviour toward other students at age 13.

12 Oct 2016

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Combining multiple non-invasive measures, researchers at University of California San Diego School of Medicine describe a novel method to quantify the progression of nonalcoholic fatty liver disease (NAFLD) to its more dangerous and deadly states — advanced fibrosis and cirrhosis.

12 Oct 2016

Study on common bacterium presents new pathway to combat gastric cancers

A common bacterium that more than half of people have in their gut can use hydrogen gas present in the gastrointestinal tract to inject a cancer-causing toxin into otherwise healthy cells, according to a recently published study led by University of Georgia researchers.

12 Oct 2016

Yale researchers define genetic landscape of rare, aggressive carcinosarcomas

In a major breakthrough for ovarian and uterine cancers, Yale researchers have defined the genetic landscape of rare, highly aggressive tumors called carcinosarcomas (CSs), pointing the way to possible new treatments.

12 Oct 2016

Medical Research News

Genome engineering-based methods pave way for new treatment of patients with sickle cell disease

New systems-thinking approach could help improve health of the U.S. population

Clinical trial finds women with heavy periods can be greatly helped by GP-prescribed treatments

Common drug for allergies and asthma could prevent fibrosis, reduce need for liver transplants

Study suggests possibility for small molecule drug/antibody combinatorial therapy to treat neuroblastoma

Community outreach workers may help increase HBV vaccination rates to cut risk of liver cancer

Researchers identify how amyloid beta linked to Alzheimer's disease could trigger Parkinson's

Research findings raise hope for better treatment of diabetic wounds

Study identifies mechanistic link between maternal obesity and childhood hypertension

Heavy cannabis users have large reduction in bone density, increased risk of bone fractures

Warm childhood environments linked to secure marriages in late life

UVA physicists develop new imaging method with potential for high-resolution medical diagnostics

Children who experience family, environmental stressors more likely to be diagnosed with ADHD

NDSU investigator receives $3.7 million grant for bariatric surgery research

Novel surgical approach can help remove diseased gallbladder through single, small incision

Fetal brains use unique amplifier to transmit signals, research shows

Excessive televiewing in early childhood can lead to risk of social impairment during adolescence

Novel method can quantify progression of NAFLD to more advanced fibrosis and cirrhosis

Study on common bacterium presents new pathway to combat gastric cancers

Yale researchers define genetic landscape of rare, aggressive carcinosarcomas

Microphysiological systems in drug discovery

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

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