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Huntington's disease monkey model embodies full array of symptoms similar to human patients

Transgenic Huntington's disease monkeys display a full spectrum of symptoms resembling the human disease, ranging from motor problems and neurodegeneration to emotional dysregulation and immune system changes, scientists at Yerkes National Primate Research Center, Emory University report.

21 Jul 2016

BET inhibitor treatment decreases lung inflammation in mice

Patients with cystic fibrosis (CF) suffer from chronic respiratory infections, primarily caused by Pseudomonas aeruginosa, which lead to airway inflammation and damage.

21 Jul 2016

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Although antiretroviral therapy (ART) can reduce the amount of HIV in the blood to an undetectable level in most chronically infected people, it cannot eliminate reservoirs of HIV that persist in latently infected immune cells.

21 Jul 2016

Scientists demonstrate synapses between specific neuron types form clusters

The cerebral cortex resembles a vast switchboard. Countless lines carrying information about the environment, for example from the sensory organs, converge in the cerebral cortex.

21 Jul 2016

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Neutron crystallography allows us to determine the three-dimensional structures of biological macromolecules, such as proteins, by means of the diffraction of neutrons from the regularly spaced atoms of a crystal.

21 Jul 2016

Study identifies ADAM33 gene as novel target for preventing asthma

Scientists at the University of Southampton have discovered a potential and novel way of preventing asthma at the origin of the disease, a finding that could challenge the current understanding of the condition.

21 Jul 2016

New imaging tool may help detect presence of androgen receptor in prostate cancer patients

Prostate cancer is one of the most common cancers in men. Tumor growth is critically regulated by the androgen receptor, and treatment strategies to lower androgens, such as testosterone, are a mainstay of clinical treatment.

21 Jul 2016

Improving efficiency of health facilities could extend ART to many people living with HIV

Health facilities in Kenya, Uganda, and Zambia could extend life-sustaining antiretroviral therapy (ART) to hundreds of thousands of people living with HIV if facilities improved the efficiency of service delivery.

21 Jul 2016

Innovative technology streamlines clinical trial management, improves patient experience

The University of Alabama at Birmingham recently integrated a clinical research management system that allows patient consent, data and documents from multiple sites to automatically flow from the the Enroll e-Consenting tablet application by Mytrus into the Velos eResearch interface.

21 Jul 2016

HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis

Researchers at Hospital for Special Surgery have launched a study to determine if a treatment using stem cells could help people with painful knee arthritis.

21 Jul 2016

Study finds no significant decline in indoor tanning use among school children after under-17 ban

Research from Rutgers Cancer Institute of New Jersey and Rutgers School of Public Health shows no significant decline in indoor tanning rates among children under age 17 following a ban on such use in New Jersey enacted in 2013.

21 Jul 2016

Study provides new insights into real-world use of PrEP

Several studies presented today in an official press conference at the 21st International AIDS Conference in Durban provided new insights on the use of PrEP among a broad range of populations.

21 Jul 2016

Researchers identify genetic causes underlying higher rate of melanoma in men

A study led by researchers at Universitat Jaume I de Castellón has identified one of the genetic causes underlying the higher rate of melanoma in men. The results have been published in Biology of Sex Differences.

21 Jul 2016

New report urges policy makers to act against excessive energy drinks consumption by children, teenagers

UK policy makers must act against excessive energy drinks consumption by children and young people, argues a new report published by the Food Research Collaboration, an initiative of the Centre for Food Policy.

21 Jul 2016

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

A collaboration between the University of Leicester and global pharmaceutical company GlaxoSmithKline has been established to discover and develop novel medicines to treat aggressive forms of blood cancer.

21 Jul 2016

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

Long-term treatment with broad spectrum antibiotics decreased levels of amyloid plaques, a hallmark of Alzheimer's disease, and activated inflammatory microglial cells in the brains of mice in a new study by neuroscientists from the University of Chicago.

21 Jul 2016

New SACN guidelines recommend daily 10 micrograms intake of Vitamin D

The Scientific Advisory Committee on Nutrition (SACN) has published a report advising that anybody aged over one year should have a vitamin D intake of 10 micrograms a day throughout the year.

21 Jul 2016

Scientific review cautions against unnecessary use of antioxidant supplements

The lay press and thousands of nutritional products warn of oxygen radicals or oxidative stress and suggest taking so-called antioxidants to prevent or cure disease.

21 Jul 2016

New study offers hypothesis why obese patients fare worse during cancer treatment

Across many cancer types, obese patients fare worse than leaner patients. Now a University of Colorado Cancer Center study published in the journal Cell Stem Cell offers a compelling hypothesis why: researchers found that leukemia stem cells "hide" in fatty tissue, even transforming this tissue in ways that support their survival when challenged with chemotherapy. It is as if leukemia stem cells not only use fatty tissue as a robbers' cave to hide from therapy, but actively adapt this cave to their liking.

21 Jul 2016

Researchers show porous silicon nanoparticles could be harmless to diagnose and treat cancer

The Lomonosov Moscow State University researchers in collaboration with their German colleagues have succeeded in proving that silicon nanoparticles can be applied to diagnose and cure cancer.

21 Jul 2016

Medical Research News

Huntington's disease monkey model embodies full array of symptoms similar to human patients

BET inhibitor treatment decreases lung inflammation in mice

Combining ART with immune-enhancing treatment may destabilize HIV reservoirs

Scientists demonstrate synapses between specific neuron types form clusters

Neutrons key to discovering new HIV drugs? An interview with Dr Matthew Blakeley

Study identifies ADAM33 gene as novel target for preventing asthma

New imaging tool may help detect presence of androgen receptor in prostate cancer patients

Improving efficiency of health facilities could extend ART to many people living with HIV

Innovative technology streamlines clinical trial management, improves patient experience

HSS researchers launch new study to find if stem cell treatment could help people with knee arthritis

Study finds no significant decline in indoor tanning use among school children after under-17 ban

Study provides new insights into real-world use of PrEP

Researchers identify genetic causes underlying higher rate of melanoma in men

New report urges policy makers to act against excessive energy drinks consumption by children, teenagers

GSK and University of Leicester team up to develop novel drugs to treat blood cancer

Long-term antibiotic treatment slows progression of Alzheimer's disease through changes in gut bacteria

New SACN guidelines recommend daily 10 micrograms intake of Vitamin D

Scientific review cautions against unnecessary use of antioxidant supplements

New study offers hypothesis why obese patients fare worse during cancer treatment

Researchers show porous silicon nanoparticles could be harmless to diagnose and treat cancer

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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