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Common breast cancer treatment less effective for smokers compared to non-smokers

We know that individuals who smoke take major health risks. Now a new research study from Lund University in Sweden shows that common treatment for breast cancer works less well in patients who smoke, compared to non-smokers.

20 Jun 2016

TUM researchers uncover molecular mechanism of thalidomide

In the 1950s, thalidomide (Contergan) was prescribed as a sedative drug to pregnant women, resulting in a great number of infants with serious malformations. Up to now, the reasons for these disastrous birth defects have remained unclear.

20 Jun 2016

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

CarThera, a French company based at the Brain and Spine Institute, that designs and develops innovative ultrasound-based medical devices to treat brain disorders, today announces the publication in Science Translational Medicine of a scientific paper on initial successes in disrupting the blood-brain barrier (BBB) with the use of ultrasound.

20 Jun 2016

Study suggests how expression, function of nAChRs regulated in AD

Nicotinic acetylcholine receptors (nAChRs) have been pursued for decades as potential molecular targets to treat cognitive dysfunction in Alzheimer's disease (AD) due to their demonstrated role in processes underlying cognition such as synaptic facilitation, and theta and gamma wave activity.

20 Jun 2016

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Measuring antibody levels in the blood could be used to detect a person's heart attack risk after researchers, part-funded by the British Heart Foundation, discovered that higher levels of these antibodies are linked to a lower heart attack risk.

20 Jun 2016

Nonopioid interventional options for chronic pain not covered by insurance in few U.S. states

Recent studies have shown significant therapeutic value from the use of high-frequency - 10,000 (HF-10) spinal cord stimulation (SCS) for patients experiencing chronic back and leg pain.

20 Jun 2016

Brain imaging finds link between blood-brain barrier disruption and severity of bleeding after stroke therapy

In a study of stroke patients, investigators confirmed through MRI brain scans that there was an association between the extent of disruption to the brain's protective blood-brain barrier and the severity of bleeding following invasive stroke therapy. The results of the National Institutes of Health-funded study were published in Neurology.

20 Jun 2016

Scientists study fundamentals of tumour surveillance by immune system in mice models

The body's defences detect and eliminate not only pathogens but also tumour cells. Natural killer cells (NK-Cells) are specifically activated by chemical messengers, the Cytokines, to seek and destroy tumour cells.

20 Jun 2016

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Mothers of children with autism and were diagnosed with metabolic conditions during pregnancy, particularly gestational and type 2 diabetes, were more likely to have anti-fetal brain autoantibodies in their blood compared to healthy women of children with autism.

20 Jun 2016

Regular exercise may help improve muscle repair response in older adults

Here's another reason why you should hit the gym regularly as you grow older: A new report appearing online in The FASEB Journal shows that regular exercise plays a critical role in helping muscles repair themselves as quickly as possible after injury.

20 Jun 2016

Researchers uncover mechanism of two-in-one sensor protein KdpD

Uptake of potassium by bacteria is regulated by a single protein that senses the concentration of this cation both inside the cell and in the external medium, and controls the expression of the corresponding transport protein accordingly.

20 Jun 2016

E-cigarettes play key role in reducing smoking among youngsters

A new study from the UK Centre for Substance Use Research, being presented today at the Global Forum on Nicotine, shows e-cigarettes are playing an important role in reducing the likelihood of young people smoking, in many cases acting as a 'roadblock' to combustible tobacco.

20 Jun 2016

ECDC sketches actions to reduce public health risks of mcr-1 gene spread

The recently recognised global distribution of the mcr-1 gene poses a substantial public health risk to the EU/EEA. The gene is widespread in several continents and has been detected in bacteria isolated from multiple different sources such as food-producing animals, food, the environment and humans.

20 Jun 2016

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

Pathologists have been largely diagnosing disease the same way for the past 100 years, by manually reviewing images under a microscope. But new work suggests that computers can help doctors improve accuracy and significantly change the way cancer and other diseases are diagnosed.

20 Jun 2016

New research program seeks to elucidate traumatic memories of 2015 terrorist attacks in Paris

How will the traumatic events of the terrorist attacks of 13 November 2015 evolve in people's memories, whether collective or individual? How does individual memory feed on collective memory and vice versa?

20 Jun 2016

Cabozantinib extends advanced RCC overall survival

Patients with advanced or metastatic renal cell carcinoma derive a significant overall survival benefit from second-line treatment with the multi-tyrosine kinase inhibitor cabozantinib relative to everolimus.

18 Jun 2016

Overweight in adolescence portends early heart failure

A study of Swedish army conscripts shows that men who have an increased body mass index (BMI) at the age of 18 years risk early heart failure. And the increased risk began at a BMI gener ...

18 Jun 2016

Post-MI angina linked to increased late readmission risk

US researchers are calling for greater surveillance and treatment of post-myocardial infarction angina after their findings show an increased risk of late readmission among patients with angina symptoms at 30 days.

18 Jun 2016

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Somatic mutations in the helicase-encoding ERCC2 gene are associated with response to neoadjuvant cisplatin-based chemotherapy in patients with muscle-invasive urothelial bladder carcinoma.

17 Jun 2016

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

Low levels of BPA exposure may be considered safe, but new research published online in The FASEB Journal, suggests otherwise. In the report, researchers from Yale show that the genome is permanently altered in the uterus of mice that had been exposed to BPA during their fetal development.

17 Jun 2016

Medical Research News

Common breast cancer treatment less effective for smokers compared to non-smokers

TUM researchers uncover molecular mechanism of thalidomide

Scientific paper supports concept of CarThera's intracranial ultrasound implant to disrupt blood-brain barrier

Study suggests how expression, function of nAChRs regulated in AD

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Nonopioid interventional options for chronic pain not covered by insurance in few U.S. states

Brain imaging finds link between blood-brain barrier disruption and severity of bleeding after stroke therapy

Scientists study fundamentals of tumour surveillance by immune system in mice models

Diabetic mothers three times more likely to have anti-fetal brain autoantibodies

Regular exercise may help improve muscle repair response in older adults

Researchers uncover mechanism of two-in-one sensor protein KdpD

E-cigarettes play key role in reducing smoking among youngsters

ECDC sketches actions to reduce public health risks of mcr-1 gene spread

Researchers develop AI-powered systems to make pathologic diagnoses more accurate

New research program seeks to elucidate traumatic memories of 2015 terrorist attacks in Paris

Cabozantinib extends advanced RCC overall survival

Overweight in adolescence portends early heart failure

Post-MI angina linked to increased late readmission risk

ERCC2 validated as chemotherapy response biomarker in bladder cancer

Fetal BPA exposure leads to harmful change in adult uterine response to estrogens

How can machine learning accelerate neuroscience behavior studies?

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