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Carfilzomib therapy shows promise for pre-kidney transplant patients

Early findings by researchers at the University of Cincinnati College of Medicine suggest that the use of a second generation cancer drug, carfilzomib, may provide an improved approach for the reduction of antibodies in potential kidney transplant candidates.

10 Jun 2016

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors.

10 Jun 2016

New qPAINT technology helps develop more precise, less expensive microscopes

Knowing the exact number of molecules located at specific junctures in cells can be a critical measure of health as well as disease. For example, abnormally high numbers of growth factor receptors on cells can be an indication of cancerous and precancerous states; specific proteins located at the junction where neurons connect in the brain may affect brain function as they accumulate or disperse.

10 Jun 2016

First limbal stem cell transplant performed in Ireland

On Tuesday 7th June 2016, the first Limbal Stem Cell transplant in Ireland was performed by Mr. William Power, Consultant Ophthalmologist at the Royal Victoria Eye and Ear Hospital in Dublin.

10 Jun 2016

Study: About 40% of Hispanic adults with colorectal cancer use CIH

A study of complementary and integrative health (CIH) use among Hispanic adults with colorectal cancer found that about 40% reported experience with CIH.

10 Jun 2016

Study captures interactions of HIV-infected immune cells in living animal

By watching brightly glowing HIV-infected immune cells move within mice, researchers at the Icahn School of Medicine at Mount Sinai have shown how infected immune cells latch onto an uninfected sister cell to directly transmit newly minted viral particles.

10 Jun 2016

Researchers discover AF1q protein linked to multiple myeloma, EMD

A group of researchers from the University of Louisville, Japan and Austria is the first to identify a protein, AF1q, associated with multiple myeloma and a condition that occurs in approximately one-fourth of very aggressive multiple myeloma, extramedullary disease or EMD.

10 Jun 2016

Study highlights role of intestinal calcium absorption in kidney stone formation

Measuring intestinal calcium absorption may help to identify individuals who are prone to develop kidney stones, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology.

10 Jun 2016

Measuring specific proteins in blood samples may help track progression of dementias

Reliable information can be obtained on the progression of dementias by measuring specific proteins in the blood and cerebrospinal fluid. A test of this kind is especially significant to the development of new therapies, as reported in the journal Neuron by scientists from the University of Basel and University Hospital Basel, along with international colleagues.

10 Jun 2016

Utah researchers find way to use power of protease to destroy budding AIDS virus

When new AIDS virus particles bud from an infected cell, an enzyme named protease activates to help the viruses mature and infect more cells. That's why modern AIDS drugs control the disease by inhibiting protease.

10 Jun 2016

Lack of signaling protein CXCR4 may halt cancer development

Zebrafish-human communication shows that cancer cells lacking a signaling protein are less able to develop aggressive metastatic properties.

10 Jun 2016

OTC remains best option to preserve fertility of prepubertal girls treated with gonadotoxic chemotherapy

Ovarian tissue cryopreservation (OTC), harvesting and freezing ovarian tissue, is the most promising complication-free strategy to preserve potential fertility in pre-pubescent girls undergoing sterilising chemotherapy, according to a 13 year study by Fanny Chambon et al. in the journal, Human Fertility.

10 Jun 2016

Social contact with older adults can reduce ageism among young people

Young people are less likely to be ageist when their friends have friendships with older adults, research led by psychologists at the University of Kent has shown.

10 Jun 2016

Enhancing motility of skin cells could help promote wound healing

Skin cells typically spend their entire existence in one place on your body. But Washington State University researchers have seen how the cells will alter the proteins holding them in place and move to repair a wound.

10 Jun 2016

New study finds underutilization of PR therapy among older COPD patients

A new study from The University of Texas Medical Branch at Galveston investigating trends on the use of pulmonary rehabilitation therapy among older adults with chronic obstructive pulmonary disease found that this therapy was underutilized, despite its health benefits and cost effectiveness.

10 Jun 2016

Intrinsic subtyping of breast cancer can aid prognosis, treatment of tumor patients

Published in JAMA Oncology, Principal Investigator of Vall d´Hebron Institute of Oncology´s Translational Genomics Group, Team Leader of translational genomics and targeted therapeutics in solid tumors at the August Pi I Sunyer Biomedical Research Institute, and Head of Medical Oncology at the Hospital Clínic in Barcelona, Aleix Prat has led a study showing the intrinsic subtyping of breast cancer by means of a genomic test as the most important prognostic factor in advanced or metastatic hormone-sensitive breast cancer.

10 Jun 2016

Unique method opens door to development of simple diagnostic tests for myriad diseases

Researchers at the University of Pittsburgh have developed a unique method for detecting antibodies in the blood of patients in a proof-of-principle study that opens the door to development of simple diagnostic tests for diseases for which no microbial cause is known, including auto-immune diseases, cancers and other conditions.

10 Jun 2016

Smoking, obesity lower chances of achieving sustained remission in early RA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that the likelihood of achieving sustained remission in early rheumatoid arthritis (RA) is significantly lower in patients who smoke and who are obese.

10 Jun 2016

Study shows rheumatologists underestimate disease severity in OA patients

The results of a study presented today at the European League Against Rheumatism Annual Congress showed patients with osteoarthritis (OA) are more likely to have the impact of their condition underestimated by rheumatologists than patients with Rheumatoid Arthritis (RA).

10 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

Medical Research News

Carfilzomib therapy shows promise for pre-kidney transplant patients

RNA editing enzyme ADAR1 may play role in regeneration of leukemia stem cells

New qPAINT technology helps develop more precise, less expensive microscopes

First limbal stem cell transplant performed in Ireland

Study: About 40% of Hispanic adults with colorectal cancer use CIH

Study captures interactions of HIV-infected immune cells in living animal

Researchers discover AF1q protein linked to multiple myeloma, EMD

Study highlights role of intestinal calcium absorption in kidney stone formation

Measuring specific proteins in blood samples may help track progression of dementias

Utah researchers find way to use power of protease to destroy budding AIDS virus

Lack of signaling protein CXCR4 may halt cancer development

OTC remains best option to preserve fertility of prepubertal girls treated with gonadotoxic chemotherapy

Social contact with older adults can reduce ageism among young people

Enhancing motility of skin cells could help promote wound healing

New study finds underutilization of PR therapy among older COPD patients

Intrinsic subtyping of breast cancer can aid prognosis, treatment of tumor patients

Unique method opens door to development of simple diagnostic tests for myriad diseases

Smoking, obesity lower chances of achieving sustained remission in early RA patients

Study shows rheumatologists underestimate disease severity in OA patients

New RNA aptamer can prevent pathogenic protein misfolding

CoppaFeel!: Breast Cancer Doesn’t Discriminate, So Why Should Awareness?

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

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