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Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease

A new study has shown that myricitrin, a flavinoid with antioxidant and anti-inflammatory activity that is present inedible plants and fruit, can protect mouse brains from the loss of dopamine-producing neurons caused by neurotoxicity.

7 Jun 2016

Eculizumab drug provides new hope for kidney failure patients

Surgeons at the University of Illinois Hospital & Health Sciences System have — for the first time — used an orphan drug to prevent rejection of a kidney transplanted from a living donor with a mismatched blood type.

7 Jun 2016

Newspaper stories paint unfair portrait by linking mental illness and violence

Nearly four in 10 news stories about mental illness analyzed by Johns Hopkins Bloomberg School of Public Health researchers connect mental illness with violent behavior toward others, even though less than five percent of violence in the United States is directly related to mental illness.

7 Jun 2016

Research shows weekend admissions in NHS hospital can affect AF patients

Patients suffering from the most common form of heart rhythm disorder who are admitted to NHS hospital over the weekend face a higher risk of dying over the next five years than those admitted during normal hours.

7 Jun 2016

Human stem cells restore motor function in chronic stroke patients

Injecting modified, human, adult stem cells directly into the brains of chronic stroke patients proved not only safe but effective in restoring motor function, according to the findings of a small clinical trial led by Stanford University School of Medicine investigators.

7 Jun 2016

Combination immunotherapy may be better than one to combat metastatic melanoma

A new metastatic melanoma study suggests that a combination of two immunotherapies may be better than one.

7 Jun 2016

Unlocking the first gene to cause otosclerosis: an interview with Dr Ralph Holme

Otosclerosis is a common cause of hearing loss, particularly amongst young adults. It normally starts in their 20s or 30s and it affects about 1 in 200 hundred people. In the UK, about 300,000 people are affected by the condition.

7 Jun 2016

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

Pancreatic ductal adenocarcinoma, the most common of pancreatic cancers, is extraordinarily lethal, with a 5-year survival rate of just 6 percent. Chemotherapy treatments are poorly effective, in part due to a high degree of drug-resistance to currently used regimens.

7 Jun 2016

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

Research into kidney regeneration, an organ that has been extremely difficult to regenerate, has taken a great stride forward with research coming out of a collaboration between Kumamoto University, Japan and the National Cancer Institute of the US.

7 Jun 2016

HKUST study suggests innate immune response plays vital role in pathogenesis of AD

Alzheimer's disease (AD) is a devastating condition with no known effective treatment. The disease is characterized by memory loss as well as impaired locomotor ability, reasoning, and judgment. Emerging evidence suggests that the innate immune response plays a major role in the pathogenesis of AD.

7 Jun 2016

Loughborough research reveals most effective way of boosting muscle strength

Engaging in short, explosive leg contractions is the most effective way of strengthening muscles, Loughborough research reveals.

7 Jun 2016

Taking hormone therapy drugs for additional five years improves outcomes in breast cancer patients

Breast cancer patients significantly benefit by taking hormone therapy drugs called aromatase inhibitors for an additional five years, according to a major study presented at the Plenary Session of the American Society of Clinical Oncology annual meeting in Chicago and published in the New England Journal of Medicine.

7 Jun 2016

Researchers find increased cancer incidence among patients with primary immunodeficiency disorders

Primary immunodeficiency disorders are a group of more than 300 single gene defects that affect the role of the immune system and prevent it from functioning properly. When Roswell Park Cancer Institute researchers evaluated the overall and site-specific incidence of cancer among patients registered in the United States Immune Deficiency Network, they found increased cancer incidence rates among patients with primary immunodeficiency diseases — and, in particular, a significant increase in lymphoma cases.

7 Jun 2016

Epigenomic alterations play key role in triggering obesity-induced diabetes

Obesity is a risk factor for developing type 2 diabetes, yet not all obese humans develop the disease. In a new study, researchers from the Karolinska Institutet in Sweden and from the Institute of Health and Medical Research in France have identified epigenomic alterations that are associated with inflammation and type 2 diabetes

7 Jun 2016

Genes of healthy leanness could lead to new approach to treating obesity-related diabetes

People with type 2 diabetes could be helped by the discovery of a gene linked to leanness.

7 Jun 2016

Northwestern Medicine scientists link TMEM230 gene mutations to Parkinson's disease development

Northwestern Medicine scientists have discovered a new cause of Parkinson's disease -- mutations in a gene called TMEM230. This appears to be the third gene definitively linked to confirmed cases of the common movement disorder.

7 Jun 2016

Spider venom helps investigate pain signals experienced by irritable bowel syndrome patients

Spiders have helped researchers from Australia and the US discover a new target for irritable bowel syndrome pain.

7 Jun 2016

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn't just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients.

7 Jun 2016

$One-third of osteoporotic women taking oral bisphosphonates have elevated risk for bone fracture$

One-third of osteoporotic women taking oral bisphosphonates have elevated risk for bone fracture

More than 53 million Americans age 50 and older, primarily women, have osteoporosis or are at high risk for the condition due to low bone density. A recent study of oral bisphosphonates, the most commonly prescribed osteoporosis treatment, found that approximately a third of women prescribed these drugs continue to be at elevated risk for bone fracture, an outcome that may have several origins.

7 Jun 2016

Higher blood levels of methotrexate impair executive functioning in long-term pediatric ALL survivors

Research from St. Jude Children's Research Hospital suggests that pediatric leukemia patients exposed to higher concentrations of the chemotherapy drug methotrexate are more likely to struggle with mental flexibility, organization and related skills as long-term survivors.

7 Jun 2016

Medical Research News

Myricitrin may play role in preventing neuronal degeneration in Parkinson's disease

Eculizumab drug provides new hope for kidney failure patients

Newspaper stories paint unfair portrait by linking mental illness and violence

Research shows weekend admissions in NHS hospital can affect AF patients

Human stem cells restore motor function in chronic stroke patients

Combination immunotherapy may be better than one to combat metastatic melanoma

Unlocking the first gene to cause otosclerosis: an interview with Dr Ralph Holme

Innovative mouse model could provide new strategy to arrest growth of pancreatic cancer

Researchers establish new method to culture kidney progenitor cells for regenerative medicine

HKUST study suggests innate immune response plays vital role in pathogenesis of AD

Loughborough research reveals most effective way of boosting muscle strength

Taking hormone therapy drugs for additional five years improves outcomes in breast cancer patients

Researchers find increased cancer incidence among patients with primary immunodeficiency disorders

Epigenomic alterations play key role in triggering obesity-induced diabetes

Genes of healthy leanness could lead to new approach to treating obesity-related diabetes

Northwestern Medicine scientists link TMEM230 gene mutations to Parkinson's disease development

Spider venom helps investigate pain signals experienced by irritable bowel syndrome patients

Antiinflammatory drug HUMIRA enhances specific TNF function in rheumatoid arthritis patients

One-third of osteoporotic women taking oral bisphosphonates have elevated risk for bone fracture

Higher blood levels of methotrexate impair executive functioning in long-term pediatric ALL survivors

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