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Early exposure to nicotine can affect formation of connections between brain cells long after birth

Early exposure to nicotine can trigger widespread genetic changes that affect formation of connections between brain cells long after birth, a new Yale-led study has found. The finding helps explains why maternal smoking has been linked to behavioral changes such as attention deficit and hyperactivity disorder, addiction and conduct disorder.

30 May 2016

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach in a paper, "Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient," that will be published online May 30 in The Journal of Experimental Medicine.

30 May 2016

Experts discuss new therapy options for stroke treatment at EAN Congress

There are more well-founded therapy options for the treatment of strokes than ever before. Care has to be reorganised before these innovations are actually used on patients. At the Congress of the European Academy of Neurology in Copenhagen, experts are discussing just how to do that successfully - from guidelines for the use of thrombectomy procedures all the way to the structure and expansion of stroke care units.

30 May 2016

New study sheds light on link between gut microbiome and the brain

Intestinal bacteria that can boost bravery or trigger multiple sclerosis: An increasing body of research results confirms the importance of the "gut-brain axis" for neurology and indicates that the triggers for a number of neurological diseases may be located in the digestive tract.

30 May 2016

Study finds no increased risk of stroke for football fans

Being excited for your team, rooting them on and suffering vicariously with them are the grand emotions that wash over spectators of football matches. If this increases the risk of stroke remains to be elucidated, as the number of strokes that occur on days with major matches is not significantly higher than on days when no football is played.

30 May 2016

Premature babies have lower peak bone mass as adults

Among the many important processes that happen during a woman's last few weeks of pregnancy is the transfer of calcium to the growing foetus to boost bone development.

30 May 2016

Noise in ICUs exceeds recommended levels, disturbs patients and care givers

A study presented at Euroanaesthesia 2016 shows that noise levels in the Intensive Care Unit (ICU) can go well above recommended levels, disturbing both patients and the medical teams that care for them.

30 May 2016

Initiatives to improve adolescent, young adult cancer outcomes justified

Analysis of the EUROCARE-5 data shows that although survival for adolescents and young adults with cancer has improved overall, the survival rates for certain malignancies still lag behind those for children.

28 May 2016

Trial results underestimate anticoagulant bleeding risk

A study in The BMJ demonstrates that estimates of major bleeding risk in patients taking anticoagulants in clinical trials are unlikely to reflect the reality of clinical practice.

28 May 2016

European cardiovascular prevention guidelines emphasise population approaches

The European Society of Cardiology has updated its cardiovascular disease prevention guidelines to include, for the first time, population approaches to be implemented by legislators, schools and workplaces.

28 May 2016

SIPPET study may have implications for treatment of patients with severe hemophilia A

SIPPET, a study which involved 42 centers in 14 countries in Europe, North and South America, Africa and Asia was designed to definitively settle the long-debated question whether factor VIII concentrates from different sources (plasma-derived containing VWF or recombinant technology) differ in risk of inhibitor development in previously untreated children (PUPs) with severe hemophilia A.

28 May 2016

NMSU researchers seek Aedes aegypti mosquito to map Zika virus transmission

While the rest of the world is keeping its distance from the mosquito that carries the Zika virus, two New Mexico State University professors are seeking out this mosquito, which carries not only Zika but also a host of other diseases as well.

28 May 2016

Oncologists to present latest research findings at ASCO annual meeting

Oncologists from NewYork-Presbyterian, Columbia University Medical Center and Weill Cornell Medicine will discuss their latest research findings at the American Society for Clinical Oncology annual meeting, June 3-7 in Chicago.

28 May 2016

PNNL scientists play central role in National Microbiome Initiative

Scientists at the U.S. Department of Energy's Pacific Northwest National Laboratory are playing a central role as the nation devotes more than $500 million to understand communities of microorganisms and their role in climate science, food production and human health.

28 May 2016

Researchers find Aspergillus as interesting target for discovery of novel drugs

The fungus Aspergillus fumigatus produces a group of previously unknown natural products. With reference to plant isoquinoline alkaloids, these substances have been named fumisoquins.

28 May 2016

Growing opportunities for artificial brain enhancement bring humans closer to becoming cyborgs

Our excitement with and rapid uptake of technology - and the growing opportunities for artificial brain enhancement - are putting humans more firmly on the path to becoming cyborgs, according to evolution experts from the University of Adelaide.

28 May 2016

New tool that simulates user interaction can help develop accessible ICT applications for people with disabilities

A tool developed by researchers from UPM allows us to assess usability during the design and testing process of accessible ICT-based applications.

28 May 2016

University of Leicester researcher awarded grant to develop bacteriophages to target infant Shigella

A University of Leicester researcher has been awarded funding to develop bacteriophages to target bacterial infant diarrhoea in the developing world where it causes significant mortality.

28 May 2016

Surrogate endpoints for cancer drug approval often lack formal empirical verification

Surrogate endpoints used to support the majority of new cancer drugs approved in the U.S. often lack formal study, according to the authors of a study published in the June issue of Mayo Clinic Proceedings.

28 May 2016

New research estimates unmet surgical needs of forcibly displaced persons

New research from the Johns Hopkins Bloomberg School of Public Health suggests that the world's estimated 60 million refugees, displaced from their homes due to conflict, persecution or human rights violations, may need at least 2.78 million surgeries a year, something thought to be very difficult to arrange in the midst of their upheaval.

28 May 2016

Medical Research News

Early exposure to nicotine can affect formation of connections between brain cells long after birth

Oncologists combine two different types of immunotherapy to successfully treat metastatic melanoma

Experts discuss new therapy options for stroke treatment at EAN Congress

New study sheds light on link between gut microbiome and the brain

Study finds no increased risk of stroke for football fans

Premature babies have lower peak bone mass as adults

Noise in ICUs exceeds recommended levels, disturbs patients and care givers

Initiatives to improve adolescent, young adult cancer outcomes justified

Trial results underestimate anticoagulant bleeding risk

European cardiovascular prevention guidelines emphasise population approaches

SIPPET study may have implications for treatment of patients with severe hemophilia A

NMSU researchers seek Aedes aegypti mosquito to map Zika virus transmission

Oncologists to present latest research findings at ASCO annual meeting

PNNL scientists play central role in National Microbiome Initiative

Researchers find Aspergillus as interesting target for discovery of novel drugs

Growing opportunities for artificial brain enhancement bring humans closer to becoming cyborgs

New tool that simulates user interaction can help develop accessible ICT applications for people with disabilities

University of Leicester researcher awarded grant to develop bacteriophages to target infant Shigella

Surrogate endpoints for cancer drug approval often lack formal empirical verification

New research estimates unmet surgical needs of forcibly displaced persons

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