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USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Endometrial cancer is the most common gynecologic cancer in the U.S. Most cases are diagnosed at early stage and have good prognosis. Unfortunately, some patients with early stage and low grade endometrial cancer experience recurrence - and the reasons are not entirely clear.

19 May 2016

Higher adolescent intake of saturated fat linked to higher dense breast volume in early adulthood

Consuming high amounts of saturated fat or low amounts of mono- and polyunsaturated fats as an adolescent was associated with higher breast density in young adulthood. Breast density is a risk factor for breast cancer.

19 May 2016

New research defies earlier belief that calcium channels function independently

Voltage-gated calcium channels open in unison, rather than independently, to allow calcium ions into and activate excitable cells such as neurons and muscle cells, researchers with UC Davis Health System and the University of Washington have found.

19 May 2016

Action on Hearing Loss funds new study to discover ways of preventing deafness caused by cancer drug

A widely used anti-cancer drug, cisplatin, can cause permanent and severe hearing loss, having a devastating impact on the quality of life for cancer survivors.

19 May 2016

Experts find vast mental health treatment gap in China and India

A third of the global burden of disease for mental, neurological and substance use disorders occurs in India and China – more than in all high-income countries combined – yet most people with mental disorders in these countries do not receive needed treatment.

19 May 2016

Finnish study shows systematic measures can improve sleep of professional athletes

Professional athletes suffer from sleep disorders more frequently than generally thought, however, systematic examination, counselling and individual treatment planning can improve the quality of their sleep.

19 May 2016

New mice study unveils mystery of why chronic stress, depression can lead to bone loss

A new study has helped to unveil the mystery of why chronic stress and depression can lead to bone loss and increase the risk of fractures.

19 May 2016

UK-wide study reveals AOD prescription rates for women decrease in last 10 years

A UK-wide study looking at the prescribing of anti-osteoporotic drugs (AOD) to people aged 50 years or above has found that, since 2006, AOD prescription rates for women have decreased and rates for men have levelled off, despite a growing elderly population and associated fracture risks.

19 May 2016

New lab blood test may help identify HELLP syndrome in pregnant women

A laboratory blood test developed at Johns Hopkins for the diagnosis of a rare genetic red blood cell disorder also shows promise in identifying HELLP syndrome, a life-threatening high blood pressure condition affecting 1 percent of all pregnant women that causes hypertension along with end organ damage, researchers report in the May issue of the journal Experimental Hematology.

19 May 2016

Clinicians perform UK’s first MRI-guided focused ultrasound treatment for prostate cancer

INSIGHTEC congratulates the medical team at Imperial College Healthcare NHS Trust for performing the first MR-guided focused ultrasound treatment in the United Kingdom for prostate cancer.

19 May 2016

Mini-stroke should immediately be treated with aspirin, recommend researchers

Taking aspirin immediately after experiencing stroke-like symptoms could significantly reduce the risk of a major stroke occurring in the next few days, according to a study published in The Lancet.

19 May 2016

Call for improvements in CVD risk models

There are too many poorly validated models for predicting cardiovascular disease risk in the general population, researchers report in The BMJ.

19 May 2016

Strategy choice impacts long-term mortality in bifurcation stenting

Using a provisional rather than a planned two-stent strategy for coronary bifurcation stenting may halve long-term mortality, pooled study data show.

19 May 2016

Early high-dose rhEPO fails to improve neurodevelopment in very preterm infants

Very preterm infants do not gain protection against neurodevelopmental delay with early prophylactic high-dose recombinant human erythropoietin, researchers report.

19 May 2016

Ramizol drug shows promise in treatment of Clostridium difficile infections

A scientific paper released today in the Journal of Antibiotics presents the pre-clinical development of Ramizol, a first generation drug belonging to a new class of styrylbenzene antibiotics with a novel mechanism of action.

19 May 2016

More neonatal infection research could drive forward measures to reduce infant deaths

No one knows how many newborns are dying each year due to antibiotic resistant infections, because of a lack of funding to research the issue fully, Professor Mike Sharland from St George's, University London said.

19 May 2016

Natural product darwinolide may help combat fatal MRSA infection

A serious and sometimes fatal bacterial infection, known as methicillin-resistant Staphylococcus aureus (MRSA), may soon be beatable thanks to the efforts of University of South Florida scientists who have isolated and tested an extract from a sponge found in Antarctica.

19 May 2016

Flavopiridol drug could be effective strategy to impair brain cancer growth

Glioblastoma, the most common form of brain cancer is a deadly disease for which at present there is no cure. Now, researchers have published research results that show how repurposing the old drug flavopiridol could be an effective strategy to cut short sugar availability and impair cancer growth.

19 May 2016

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

For the first time, researchers were able to demonstrate that children diagnosed with sickle cell disease showed improvement in lung function after treatment with hydroxyurea, a treatment that is underused despite its demonstrated benefits.

19 May 2016

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

A small number of patients infected by HIV spontaneously control viral replication without antiretroviral therapy, and do not develop the disease. The ability of these rare patients, known as "HIV controllers", to suppress HIV replication appears to be down to a highly effective immune response.

19 May 2016

Medical Research News

USP14 enzyme could be promising biomarker for detecting risk of endometrial cancer recurrences

Higher adolescent intake of saturated fat linked to higher dense breast volume in early adulthood

New research defies earlier belief that calcium channels function independently

Action on Hearing Loss funds new study to discover ways of preventing deafness caused by cancer drug

Experts find vast mental health treatment gap in China and India

Finnish study shows systematic measures can improve sleep of professional athletes

New mice study unveils mystery of why chronic stress, depression can lead to bone loss

UK-wide study reveals AOD prescription rates for women decrease in last 10 years

New lab blood test may help identify HELLP syndrome in pregnant women

Clinicians perform UK’s first MRI-guided focused ultrasound treatment for prostate cancer

Mini-stroke should immediately be treated with aspirin, recommend researchers

Call for improvements in CVD risk models

Strategy choice impacts long-term mortality in bifurcation stenting

Early high-dose rhEPO fails to improve neurodevelopment in very preterm infants

Ramizol drug shows promise in treatment of Clostridium difficile infections

More neonatal infection research could drive forward measures to reduce infant deaths

Natural product darwinolide may help combat fatal MRSA infection

Flavopiridol drug could be effective strategy to impair brain cancer growth

Hydroxyurea treatment improves pulmonary function decline in children with sickle cell disease

Study shows expression of high-affinity TCRs linked with spontaneous control of HIV infection

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