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Researchers highlight need for more tailored approaches to treating chronic obstructive pulmonary disease

Speakers at the recent REG 2016 Summit highlighted the need for more research into the nature and effectiveness of treatment for COPD (Chronic Obstructive Pulmonary Disease) in a real-world environment.

16 May 2016

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Ipsen S.A., a global specialty-driven pharmaceutical company, and the Institute of Molecular and Cell Biology (IMCB), a research institute under the aegis of the Agency for Science, Technology and Research (A*STAR), Singapore, today announced the signature of a research partnership to study the intracellular trafficking of botulinum neurotoxins (BoNTs) within neurons.

16 May 2016

Birmingham Women's Hospital leads the way in genomic diagnosis

Birmingham Women's Hospital (BWH) has adopted a radical new technology to make it easier to identify rare diseases by their genetic causes, leading to a faster and more accurate diagnosis for the patient. The technology being used to do this is called Sapientia™ and it is facilitating the reclassification of disease.

16 May 2016

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations.

16 May 2016

Sleeve gastrectomy can give optimal outcomes even in sweet eaters

Sleeve gastrectomy is a novel bariatric surgical procedure showing promising weight loss results, even among individuals classified as moderate or severe sweet eaters before the surgery.

15 May 2016

Better self-care and patient education can improve treatment for chronic pain

The National Pain Strategy, released this year by the U.S. Department of Health and Human Services, places strong emphasis on self management and patient education as critical pathways for improving treatment of chronic pain, especially the leading malady, back pain.

15 May 2016

Pre-existing maternal diabetes still major risk factor for congenital heart defects

The strong influence of pre-pregnancy diabetes on the likelihood of women giving birth to babies with congenital heart defects has not lessened over recent decades, say researchers.

14 May 2016

Genomic cfDNA profiling feasible in metastatic CRPC

Comprehensive genomic profiling of cell-free DNA can provide clinically useful information in men with castration-resistant prostate cancer treated with enzalutamide, research indicates.

14 May 2016

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Non-steroidal anti-inflammatory drugs (NSAIDs)—including ibuprofen, diclofenac, naproxen and others—are commonly used pain medications that are generally safe but may increase the risk of developing stomach and intestinal ulcers.

13 May 2016

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

With more than 36.9 million people infected globally, HIV continues to be a major public health issue. Those living with the virus are at an increased risk for other non-AIDS diseases, such as cardiovascular disease and cancer, and though it's not entirely clear why, this has been associated with inflammation and abnormal blood clotting.

13 May 2016

Cedars-Sinai researchers explore whether healthy lifestyle choices can slow or prevent Alzheimer's disease

Cedars-Sinai neuroscience researchers are studying whether extensive changes in lifestyle among patients with mild cognitive impairment can slow the progression of Alzheimer's disease.

13 May 2016

International study shows direct link between continued marijuana use during pregnancy and pre-term birth

International research led by the University of Adelaide has for the first time shown a direct link between continued marijuana use during pregnancy and pre-term birth.

13 May 2016

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

Arterial switch to the 12 o'clock position is associated with abnormal coronary perfusion in adolescence, reveals research presented today at EuroCMR 2016.1 Babies born with transposition of the great arteries (TGA) undergo the arterial switch operation in the first days of life.

13 May 2016

New optimised PCR tests for reliable diagnosis of Zika virus

DZIF scientists from the University of Bonn have shown that not all conventional Zika virus molecular diagnostic tests for are sufficiently reliable. They developed optimised assays and a control for quantifying viruses in blood and urine.

13 May 2016

Novel ‘Catch It’ smartphone app can help people manage their problems

In a joint project between the Universities of Liverpool and Manchester researchers have examined the initial trial of a smartphone application designed to help people manage their problems.

13 May 2016

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Myocardial fibrosis could be a future therapeutic target after researchers found it correlated with adverse cardiovascular outcomes in patients with obstructive sleep apnoea (OSA) referred for cardiac magnetic resonance (CMR).

13 May 2016

Study finds no link between weekend staffing levels and patient deaths

The ‘weekend effect’ – that patients admitted to hospital over the weekend are at an increased risk of death – overshadows a much more complex pattern of weekly changes in quality of care, which are unlikely to be addressed by simply increasing the availability of hospital doctors on Saturdays and Sundays, according to two new studies published in The Lancet.

13 May 2016

Genes linked to educational attainment expressed in the brain during prenatal development

An international group of 253 scientists has conducted one of the largest genetic studies to date and identified 74 genetic variants that are associated with the years of formal education that an individual completes.

13 May 2016

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

In a pair of related studies, chemists from the Florida campus of The Scripps Research Institute (TSRI) have identified and designed dozens of molecular “warheads” that not only can detect a key biomarker of cancer, but also could be developed into a potent new class of drug candidates for a range of diseases.

13 May 2016

Researchers identify out of control immune system linked to neurodegenerative diseases

AN out of control immune system has been identified as a possible cause of neurodegenerative diseases such as Alzheimer’s.

13 May 2016

Medical Research News

Researchers highlight need for more tailored approaches to treating chronic obstructive pulmonary disease

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Birmingham Women's Hospital leads the way in genomic diagnosis

Unlocking the dark proteome: an interview with Dr Kriwacki

Sleeve gastrectomy can give optimal outcomes even in sweet eaters

Better self-care and patient education can improve treatment for chronic pain

Pre-existing maternal diabetes still major risk factor for congenital heart defects

Genomic cfDNA profiling feasible in metastatic CRPC

Combination of COX-2-selective NSAID with PPI can reduce risk of stomach, intestinal ulcers

Altered coagulation caused by HIV virus linked to increased risk of non-AIDS diseases

Cedars-Sinai researchers explore whether healthy lifestyle choices can slow or prevent Alzheimer's disease

International study shows direct link between continued marijuana use during pregnancy and pre-term birth

Arterial switch to 12 o'clock position linked to myocardial ischaemia risk in adolescence

New optimised PCR tests for reliable diagnosis of Zika virus

Novel ‘Catch It’ smartphone app can help people manage their problems

Myocardial fibrosis linked to adverse cardiovascular outcomes in OSA patients

Study finds no link between weekend staffing levels and patient deaths

Genes linked to educational attainment expressed in the brain during prenatal development

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

Researchers identify out of control immune system linked to neurodegenerative diseases

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