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Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Catherine Aaron and Gabrielle Beaudry were 17 when they knocked on the door of the laboratory of Alex Parker, a neuroscience researcher at the University of Montreal Hospital Research Centre. While students at Collège Jean-de-Brébeuf in Montreal, they were looking for a mentor for an after-school research project. Two and half years later, the results of this scientific adventure were published today in the Journal of Agricultural and Food Chemistry.

13 Apr 2016

Daily dose of coffee could help reverse non-alcoholic fatty liver disease

Adding coffee to the diet of people with non-alcoholic fatty liver disease (NAFLD) could help reverse the condition, according to a new study conducted in mice presented at The International Liver Congress 2016 in Barcelona, Spain.

13 Apr 2016

Hospitals could reduce burden of alcohol-related liver disease through universal screening procedure

The growing burden of alcohol-related liver disease (ARLD) could be reduced if hospitals introduced a simple universal screening procedure for those attending acute and emergency hospital settings, according to a new study shared today at The International Liver Congress in Barcelona, Spain.

13 Apr 2016

HCV patients with hepatocellular carcinoma history could re-develop illness during or after taking DAAs

Data from a new study show that patients with Hepatitis C virus (HCV) taking direct-acting antiviral treatments (DAAs), who have previously fought off hepatocellular carcinoma (HCC), the most common form of liver cancer,1 had a 'high rate' of re-developing their illness.

13 Apr 2016

Studies offer alternative conclusions on efficacy of DAAs for HIV and HCV co-infected patients

Two separate studies presented today at The International Liver Congress 2016 in Barcelona, Spain have offered alternative conclusions regarding the efficacy of direct-acting antivirals (DAAs) among patients co-infected with HIV and Hepatitis C virus (HCV).

13 Apr 2016

Prime boost approach can increase possibility of combined HCV and HIV vaccination

A combined vaccination against Hepatitis C virus (HCV) and HIV moved a step closer, with the results of a study presented at The International Liver Congress 2016 in Barcelona, Spain today.

13 Apr 2016

High levels of COMP protein may lead to worse breast cancer prognosis

Research from Lund University in Sweden shows that the protein COMP, which mainly exists in cartilage, can also be found in breast cancer tumours in patients with a poor prognosis. Studies on mice also showed that COMP contributed to the development and metastasis of the breast cancer.

13 Apr 2016

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

In a new paper published by The Journal of Alzheimer's Disease, Professor Melissa Schilling, a strategy and innovation expert at the NYU Stern School of Business, uncovers a surprising new connection between diabetes and Alzheimer's disease: hyperinsulinemia, which is most often caused by prediabetes, early or undiagnosed diabetes, or obesity, is responsible for almost half of all cases of Alzheimer's disease.

13 Apr 2016

Toddlers with mobility disabilities less likely to engage in physical activity

Typical toddlers simultaneously spend about three hours a day in physical activity, play and engagement with objects such as toys, while their peers with mobility disabilities are less likely to engage in all of those behaviors at the same time, new research from Oregon State University shows.

13 Apr 2016

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Radiation is a commonly used therapeutic option to treat liver metastases, with the majority of tumors maintained under control after one year. However, some patients do not respond as well to radiation treatment, and the factors that predict patient outcomes are unclear. Moffitt Cancer Center researchers report that liver metastases have different sensitivities to radiation therapy based on the location of the primary tumor.

13 Apr 2016

Quality improvement intervention in ICUs does not reduce in-hospital mortality, study reveals

Implementation of a multifaceted quality improvement intervention with daily checklists, goal setting, and clinician prompting did not reduce in-hospital mortality compared with routine care among critically ill patients treated in intensive care units (ICUs) in Brazil, according to a study appearing in the April 12 issue of JAMA.

13 Apr 2016

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

The advent of targeted drugs for a specific type of breast cancer - HER2 positive - has dramatically improved survival rates for women with the disease. But a study led by researchers at the University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center reveals low rates of use of a targeted drug among older women with early-stage breast cancer of this type, and even lower rates for older black women.

13 Apr 2016

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

A common antihistamine used to treat symptoms of allergies and the common cold, called clemastine fumarate, partially reversed damage to the visual system in people with multiple sclerosis (MS) in a preliminary study released today that will be presented at the American Academy of Neurology's 68th Annual Meeting in Vancouver, Canada, April 15 to 21, 2016.

13 Apr 2016

Rush awarded $14.5 million NIA grant to study effects of MIND diet on Alzheimer's disease

Can a particular diet prevent Alzheimer's disease? The National Institute of Aging has invested heavily in Rush University Medical Center to try to find out.

13 Apr 2016

Umea University researchers find link between levels of DNA building blocks and colon cancer

When cells divide, the proper balance between the four DNA building blocks is required in order for the DNA to be copied without the introduction of potentially harmful mutations. Researchers at Umea University in Sweden have now shown a connection between levels of DNA building blocks - dNTPs - and colon cancer. This discovery has been published in the Proceedings of the National Academy of Sciences.

13 Apr 2016

New research shows type 2 diabetes as important risk factor for chronic liver disease

People with type 2 diabetes are at greater risk of serious liver disease than those without the condition, new research has shown.

13 Apr 2016

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Like jewels in a vault, our precious genetic material is stored in the nucleus of a cell--sequestered away from potentially damaging cellular components and toxins so that no harm can come to it. Yet over the course of a life moving through this world, our DNA does get damaged, and our cells have a host of complicated repair mechanisms to deal with such injuries.

13 Apr 2016

Researchers reach milestone in developing non-hormonal approach to male contraception

Researchers studying strategies to develop a non-hormonal approach to male contraception have reached an important milestone in their work, discovering a way to produce a key enzyme found only in sperm in sufficient quantities that they can begin designing drugs to stop the sperm from swimming to the egg.

13 Apr 2016

PTSD patients carry long-term burden even with early clinical interventions

The majority of people with post-traumatic stress disorder (PTSD) recover after early treatment -- but a substantial number still suffer for years after a traumatic event even with early clinical interventions, according to a study publishing online April 12, 2016 in The Journal of Clinical Psychiatry.

13 Apr 2016

Study finds no difference in outcomes for children raised by same-sex parents

Children raised by same-sex female parents with a stable family life show no difference in general health, emotional difficulties, coping and learning behavior, compared to children of different-sex parents in similarly stable relationships, concludes a study in the April Journal of Developmental & Behavioral Pediatrics, the official journal of the Society for Developmental and Behavioral Pediatrics. The journal is published by Wolters Kluwer.

13 Apr 2016

Medical Research News

Combination of sugar and polyphenols may prevent occurrence of neurodegenerative disease

Daily dose of coffee could help reverse non-alcoholic fatty liver disease

Hospitals could reduce burden of alcohol-related liver disease through universal screening procedure

HCV patients with hepatocellular carcinoma history could re-develop illness during or after taking DAAs

Studies offer alternative conclusions on efficacy of DAAs for HIV and HCV co-infected patients

Prime boost approach can increase possibility of combined HCV and HIV vaccination

High levels of COMP protein may lead to worse breast cancer prognosis

NYU Stern innovation expert uncovers new link between diabetes and Alzheimer's disease

Toddlers with mobility disabilities less likely to engage in physical activity

Moffitt study reports that liver metastases have different sensitivities to radiation therapy

Quality improvement intervention in ICUs does not reduce in-hospital mortality, study reveals

Study reveals low rates of targeted drug use among older black women with early-stage breast cancer

Common antihistamine may partially reverse damage to visual system in multiple sclerosis patients

Rush awarded $14.5 million NIA grant to study effects of MIND diet on Alzheimer's disease

Umea University researchers find link between levels of DNA building blocks and colon cancer

New research shows type 2 diabetes as important risk factor for chronic liver disease

Scientists use FAN1 knockout mice to refine detailed mechanisms involved in damaged DNA repair

Researchers reach milestone in developing non-hormonal approach to male contraception

PTSD patients carry long-term burden even with early clinical interventions

Study finds no difference in outcomes for children raised by same-sex parents

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