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Scientists optimize imaging and behavior techniques to monitor activity of neurons

The cerebellum is a region of the brain that plays an important role in motor control. The Purkinje cells, a class of neurons located in this region, are a major site of information integration that regulate changes in neural connections caused by varying factors such as behavior, environment, and emotions. Thus Purkinje cells provide an ideal location for studying the mechanisms necessary for cerebellum dependent motor learning.

11 Mar 2016

Researchers develop molecule that can inhibit enzyme associated with onset of stroke

Research teams separated by 14 hours and 9,000 miles have collaborated to advance prospective treatment for the world's second-leading cause of death.

11 Mar 2016

Researchers reveal how butterfly disease patients develop cutaneous squamous cell carcinomas

Fragile skin that blisters easily: 90 percent of the patients that suffer from the skin condition recessive dystrophic epidermolysis bullosa (RDEB) develop rapidly progressing cutaneous squamous cell carcinomas, a type of skin cancer, by the age of 55. 80 percent of these patients will die due to metastasis within five years after the cancer has been first detected.

11 Mar 2016

People suffering from anxiety perceive the world differently than others

People suffering from anxiety perceive the world in a fundamentally different way than others, according to a study reported in the Cell Press journal Current Biology on March 3. The research may help explain why certain people are more prone to anxiety.

11 Mar 2016

Love hormone may enhance compassion of people suffering from PTSD symptoms

Oxytocin - "the love hormone" - may enhance compassion of people suffering from symptoms of post-traumatic stress disorder (PTSD), according to new study conducted at the University of Haifa and Rambam Health Care Campus: "The fact that the present study found, that Oxytocin may improvement compassion among patients with post-traumatic stress disorder toward women, provides new evidence that oxytocin may be able to improve the social behavior of these patients," said Professor Simone Shamay-Tsoory from the Department of Psychology at the University of Haifa, who led the study.

11 Mar 2016

Scientists identify novel gene variants associated with childhood BMI

An international team of scientists has identified novel gene locations associated with childhood body mass index (BMI)--an important measurement related to childhood obesity. The meta-analysis, covering over 47,000 children, is the largest genetic study to date of childhood BMI.

11 Mar 2016

STING agonists developed to induce cellular death in B cell malignancies

In almost every mammalian cell, you will find the endoplasmic reticulum, a network of continuous membranes responsible for controlling metabolism as well as the folding, assembly and secretion of proteins.

11 Mar 2016

Excess comorbidity flagged in MS patients

Patients with multiple sclerosis have more comorbidities than would be expected for their age, even at the time of diagnosis, say researchers.

10 Mar 2016

Researchers develop new process for synthesis of potent anti-cancer agents

A team led by Rice University synthetic organic chemist K.C. Nicolaou has developed a new process for the synthesis of a series of potent anti-cancer agents originally found in bacteria.

10 Mar 2016

Brown fat may help to keep blood sugar steady in adults

Australian scientists have shown that brown fat - a special type of fat that burns energy to produce heat - may also help to keep blood sugar steady in adults.

10 Mar 2016

Maternal bacterial infections affect fetal brain anatomy and cognitive functioning after birth

St. Jude Children's Research Hospital scientists have discovered how pieces of bacterial cell wall cross the placenta and enter developing neurons, altering fetal brain anatomy and cognitive functioning after birth. The study appears today in the scientific journal Cell Host & Microbe.

10 Mar 2016

Research focuses on aging, health among Hispanic women population

Hispanic women who identify as Black or another race have worse functional health than their counterparts who identify as White, according to new research. Out today, this research is part of a new special issue of Research on Aging (ROA, a journal from SAGE Publishing) focused on aging and health among Hispanic populations in the United States and in Latin America.

10 Mar 2016

Single-step, rapid life-saving solution for pneumothorax treatment

Pneumothorax is a medical emergency: the collection of air in the pleural space separating the lung from the chest wall, causing it to collapse and resulting in suffocation. Pneumothorax is caused by chest trauma, and is believed to be responsible for over a third of preventable deaths on the battlefield and in terror attacks.

10 Mar 2016

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Some patients with breast cancer, lung cancer and leukaemia seem to fare poorly after treatment because of the effects of a particular gene, a new study finds.

10 Mar 2016

Understanding role of ethnicity, age in breast cancer prognosis

Although breast cancer is somewhat more aggressive in South Asian and Black women than in White women, this is largely due to age differences between ethnic groups in the UK, according to new research.

10 Mar 2016

Children's age at school entry may have effect on ADHD diagnosis

Attention-deficit hyperactivity disorder (ADHD) is typically diagnosed in childhood and manifests as an inability to sustain attention and control activity levels and impulse control. Some reports have indicated a prevalence of up to 15% in Western countries. Although the causes of ADHD are still unknown, a new study scheduled for publication in The Journal of Pediatrics found that a child's age at school entry may have an effect on the diagnosis of ADHD

10 Mar 2016

New procedure allows kidney transplants from incompatible donors

Researchers have found a way to stop patients rejecting kidneys that have come from incompatible donors, potentially slashing the waiting time for thousands of people in desperate need of the procedure.

10 Mar 2016

Popular kidney cancer drugs do not reduce incidence of recurrence

Two widely used targeted therapy drugs approved by the FDA for the treatment of metastatic kidney cancer—sorafenib and sunitinib—are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to a new multi-institutional study in the Lancet led by a researcher at the Abramson Cancer Center (ACC) of the University of Pennsylvania.

10 Mar 2016

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Fatness is clearly linked to cardiovascular disease, but scientists want to find why the unhealthy pair tend to go hand-in-hand and how to break up their relationship.

10 Mar 2016

Specific gene mutation may significantly reduce risk of heart attack

People with a specific gene mutation have a 50 percent lower risk of suffering a heart attack. This is what an international team of researchers headed by the cardiologist Prof. Heribert Schunkert, Medical Director of the German Heart Center at the Technical University of Munich (TUM), discovered in a broad comparative study. If this gene were switched off with medications it could reduce the risk of coronary disease significantly.

10 Mar 2016

Medical Research News

Scientists optimize imaging and behavior techniques to monitor activity of neurons

Researchers develop molecule that can inhibit enzyme associated with onset of stroke

Researchers reveal how butterfly disease patients develop cutaneous squamous cell carcinomas

People suffering from anxiety perceive the world differently than others

Love hormone may enhance compassion of people suffering from PTSD symptoms

Scientists identify novel gene variants associated with childhood BMI

STING agonists developed to induce cellular death in B cell malignancies

Excess comorbidity flagged in MS patients

Researchers develop new process for synthesis of potent anti-cancer agents

Brown fat may help to keep blood sugar steady in adults

Maternal bacterial infections affect fetal brain anatomy and cognitive functioning after birth

Research focuses on aging, health among Hispanic women population

Single-step, rapid life-saving solution for pneumothorax treatment

CYP3A7 gene may over-activate metabolism, reduce effectiveness of cancer treatments

Understanding role of ethnicity, age in breast cancer prognosis

Children's age at school entry may have effect on ADHD diagnosis

New procedure allows kidney transplants from incompatible donors

Popular kidney cancer drugs do not reduce incidence of recurrence

Scientists explore new treatment avenues to protect obese individuals from cardiovascular disease

Specific gene mutation may significantly reduce risk of heart attack

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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