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Australian researchers reveal how nutlins pave way for improving future of cancer treatment

Australian researchers have resolved a mystery about how a promising new class of anti-cancer drugs, called nutlins, work - paving the way for improving the future of cancer treatment.

22 Feb 2016

3-D map of critical protein could lead to new malaria vaccine

A three-dimensional 'map' of a critical protein that malaria parasites use to invade human red blood cells could lead to a vaccine countering the most widespread species of the parasite.

22 Feb 2016

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

For the first time, researchers have succeeded in passing an antibody through the blood-brain barrier to act as a tracer for PET imaging of the brain. This resulted in more precise information being obtained than with regular radioactive tracers. The study provides hope for more effective diagnosis of early onset Alzheimer's disease and improvements in monitoring the effects of medication.

22 Feb 2016

Researchers identify new group of powerful Ebola-fighting antibodies

A research team that included scientists from The Scripps Research Institute has identified a new group of powerful antibodies to fight Ebola virus.

22 Feb 2016

Penn researchers develop new mathematical model to estimate mutation rates in the human genome

It turns out that the type, how frequent, and where new mutations occur in the human genome depends on which DNA building blocks are nearby, found researchers from the Perelman School of Medicine at the University of Pennsylvania in an advanced online study published this week in Nature Genetics.

22 Feb 2016

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

Researchers have discovered that eliminating cells thought to aid tumor growth did not slow or halt the growth of cancer tumors. In fact, when the cancer-associated fibroblasts (CAFs), were eliminated after 10 days, the risk of metastasis of the primary tumor to the lungs and bones of mice increased dramatically.

22 Feb 2016

New article describes recent efforts made by researchers to classify bladder cancers

The ability to map the human genome has transformed how scientists and researchers classify various cancers. In the past, cancer cells were examined through a microscope and their appearance, often enhanced with dyes or other agents, was used to categorize the type of cancer.

22 Feb 2016

Patients benefit from one-on-one counseling session prior to knee or hip replacement surgery

A study at Hospital for Special Surgery finds that patients benefit from a one-on-one education session provided by a physical therapist and access to a custom web portal prior to knee or hip replacement surgery.

22 Feb 2016

New study focuses on safety of using induced pluripotent stem cells in patients

A new study led by scientists at The Scripps Research Institute and the J. Craig Venter Institute shows that the act of creating pluripotent stem cells for clinical use is unlikely to pass on cancer-causing mutations to patients.

22 Feb 2016

UGA scientists discover link between genetics and aging process

Scientists at the University of Georgia have shown that a hormone instrumental in the aging process is under genetic control, introducing a new pathway by which genetics regulates aging and disease.

22 Feb 2016

New discoveries provide further evidence for benefits of a good night's sleep

Why does sleeping on it help? This is the question tackled by new research at the University of Bristol, which reveals how brain activity during sleep sorts through the huge number of experiences we encounter every day, filing only the important information in memory.

22 Feb 2016

Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

Air pollution exposure increases obesity risk

Laboratory rats who breathed Beijing's highly polluted air gained weight and experienced cardio-respiratory and metabolic dysfunctions after three to eight weeks of exposure.

22 Feb 2016

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

Positive findings from two clinical trials have been published for the immunomodulatory agent lenalidomide in patients with heavily pretreated mantle cell lymphoma, and in adults with T-cell leukaemia-lymphoma or peripheral T-cell lymphoma.

19 Feb 2016

TSRI's Courtney Miller to receive Presidential Early Career Award for Scientists and Engineers

Courtney Miller, associate professor on the Florida campus of The Scripps Research Institute, has been selected to receive a Presidential Early Career Award for Scientists and Engineers, the highest honor bestowed by the United States government on young professionals at the outset of their independent research careers.

19 Feb 2016

Regular DBT imaging can increase cancer detection and reduce call backs

The increased cancer detection and reduced call backs associated with 3D mammography, also known as Digital Breast Tomosynthesis (DBT), can be maintained years after a patient's first DBT screening with regularly scheduled DBT imaging, according to a JAMA Oncology study published online today from researchers at the Perelman School of Medicine at the University of Pennsylvania.

19 Feb 2016

Kellogg investigators develop new nanotechnology that has potential to kill tumor cells in the eye

Researchers at the University of Michigan Kellogg Eye Center have developed a new nanoparticle that uses a tumor cell's protective mechanism against itself -- short-circuiting tumor cell metabolism and killing tumor cells.

19 Feb 2016

KU Leuven scientists improve survival of implanted bone cells

To treat a complicated, non-healing bone defect, surgeons often use an implant with living cells to promote bone repair, but the implanted cells have a small chance of surviving because they are not prepared for a lack of oxygen and nutrients at the fracture site.

19 Feb 2016

New project aims to develop low-cost device that can detect drug allergies within 30 minutes

The Universitat Politècnica de València (Polytechnic University of Valencia, UPV) is at the helm of a new Horizon2020 research project to develop a low-cost biophotonic device that can detect drug allergies within 30 minutes. Going by the acronym "Cobiophad", short for Compact Biophotonic Platform for Drug Allergy Diagnosis, it also receives funding from the European Technology Platform Photonics 21.

19 Feb 2016

Acute heart failure patients often have high levels of red meat metabolite

Patients with acute heart failure often have high levels of the metabolite trimethylamine N-oxide (TMAO) - of which red meat is a major dietary source - according to researchers from the University of Leicester.

19 Feb 2016

Medical Research News

Australian researchers reveal how nutlins pave way for improving future of cancer treatment

3-D map of critical protein could lead to new malaria vaccine

Antibody can give more precise information about Alzheimer's disease than regular radioactive tracers

Researchers identify new group of powerful Ebola-fighting antibodies

Penn researchers develop new mathematical model to estimate mutation rates in the human genome

Scientists find that lifespan of supportive cells in tumor may control cancer metastasis

New article describes recent efforts made by researchers to classify bladder cancers

Patients benefit from one-on-one counseling session prior to knee or hip replacement surgery

New study focuses on safety of using induced pluripotent stem cells in patients

UGA scientists discover link between genetics and aging process

New discoveries provide further evidence for benefits of a good night's sleep

Researchers identify common molecular alteration in glioblastoma

Air pollution exposure increases obesity risk

Lenalidomide trials show potential for expanding lymphoma, leukaemia indications

TSRI's Courtney Miller to receive Presidential Early Career Award for Scientists and Engineers

Regular DBT imaging can increase cancer detection and reduce call backs

Kellogg investigators develop new nanotechnology that has potential to kill tumor cells in the eye

KU Leuven scientists improve survival of implanted bone cells

New project aims to develop low-cost device that can detect drug allergies within 30 minutes

Acute heart failure patients often have high levels of red meat metabolite

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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