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Regrowing dopaminergic neurons may lead to new therapy for Parkinson's disease

While scientists are unsure of the molecular causes of Parkinson's Disease, they do know the disorder's tremors and other motor dysfunctions are linked to a loss of dopaminergic neurons located in the substantia nigra, a structure in the midbrain.

16 Feb 2016

Co-parenting a child has bigger impact on the immune system than flu vaccine or gastroenteritis

Raising a child together has a greater effect on your immune system than the seasonal 'flu vaccine or travellers' gastroenteritis, a study by researchers at VIB and KU Leuven in Belgium and the Babraham Institute in the UK has found.

16 Feb 2016

Study finds no beneficial effect of cancer medication on Alzheimer's disease

The cancer medication bexarotene, aka Targretin, made headlines when researchers reported that it quickly lowered Aβ in the brain, reduced amyloid plaques, and improved learning and memory in mice that mimic salient features of Alzheimer's disease (AD).

16 Feb 2016

Study: Delirium, muscle weakness and other neurological complications of sepsis poorly understood

Delirium, muscle weakness and other neurological complications of sepsis often are overlooked and poorly understood, according to a study published in the journal Current Neurology and Neurosciences Reports.

16 Feb 2016

New study to evaluate use of whole umbilical cord blood to accelerate stroke recovery

A new study will evaluate the use of whole umbilical cord blood to help the brain heal quicker after an ischemic stroke.

16 Feb 2016

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

An estimated 30 percent of the world's population is chronically infected with the parasite Toxoplasma gondii. Most people live with the infection without noticeable effect, but it can be life-threatening for people with suppressed immune systems, such as people on cancer therapies or who have HIV/AIDS.

16 Feb 2016

Scientists discover new subgroups of ILC immune cells using single-cell RNA sequencing

A relatively newly discovered group of immune cells known as ILCs have been examined in detail in a new study published in the journal Nature Immunology. By analysing the gene expression in individual tonsil cells, scientists at Karolinska Institutet in Sweden have found three previously unknown subgroups of ILCs, and revealed more about how these cells function in the human body.

16 Feb 2016

One specific microRNA has strong links to autism spectrum disorder, say TSRI scientists

Discovered only in the 1990s, microRNAs are short molecules that work within virtually all cells. Typically, each one functions as a “dimmer switch” for the expression of one or more genes, regulating a wide variety of cellular processes, including learning and memory.

16 Feb 2016

CMV-based vaccine provides protection against Ebola virus

As the latest in a series of studies, researchers at Plymouth University, National Institutes of Health and University of California, Riverside, have shown the ability of a vaccine vector based on a common herpesvirus called cytomegalovirus (CMV) expressing Ebola virus glycoprotein (GP), to provide protection against Ebola virus in the experimental rhesus macaque, non-human primate (NHP) model.

16 Feb 2016

Variations in Tie2 gene play significant role in patient responses to infections

Major infections such as influenza and bacterial sepsis kill millions of people each year, often resulting fro dangerous complications that impair the body's blood vessels. But the reasons why some patients experience these dramatic responses to infections -- and others don't -- have been unclear.

16 Feb 2016

Unpaid caregivers more likely to experience emotional, physical and financial difficulties

Unpaid family and friends who assist older people with disabilities by coordinating doctor appointments and managing medications are significantly more likely to experience emotional, physical and financial difficulties than caregivers who don't provide this type of support, new research finds.

16 Feb 2016

Proof-of-concept data for NanoString's Hyb & Seq chemistry presented at AGBT Meeting

NanoString Technologies, Inc., a provider of life science tools for translational research and molecular diagnostic products, today presented the first proof-of-concept data for its novel massively parallel single molecule sequencing chemistry, Hyb & Seq™, at the Advances in Genome Biology and Technology Meeting being held in Orlando, Florida.

From NanoString Technologies 16 Feb 2016

Research findings identify potential genetics-guided precision medicine for leukemia patients

An international research team has determined how inherited gene variations lead to severe drug toxicity that may threaten chances for a cure in children with leukemia. St. Jude Children's Research Hospital scientists led the study, results of which set the stage to expand the use of a patient's genetic make-up to tailor chemotherapy.

16 Feb 2016

St. Jude-led scientists explore better ways to use blood-forming stem cells for therapeutic interventions

A team of researchers led by scientists at St. Jude Children's Research Hospital is looking at ways to improve how blood-forming stem cells can be used for therapeutic interventions. The work has uncovered a group of genes that regulate how hematopoietic stem cells start to grow and thrive in mice. The function of many of these genes was previously unknown. Reconstitution of a robust blood-forming system is essential for recovery from many catastrophic diseases as well as from chemotherapy treatments.

16 Feb 2016

Hereditary spastic paraplegia characteristics unveiled

Researchers have detailed the characteristics of a large cohort of patients with hereditary spastic paraplegias.

15 Feb 2016

Wake Forest Baptist scientists prove feasibility of printing living tissue structures for surgical implantation

Using a sophisticated, custom-designed 3D printer, regenerative medicine scientists at Wake Forest Baptist Medical Center have proved that it is feasible to print living tissue structures to replace injured or diseased tissue in patients.

15 Feb 2016

Critical discovery holds key to explaining how 'good' gut bacteria promote health

A critical discovery about how bacteria feed on an unusual sugar molecule found in leafy green vegetables could hold the key to explaining how 'good' bacteria protect our gut and promote health.

15 Feb 2016

Hospitals serving children may face financial penalties for readmissions, researchers find

A team of researchers from children's hospitals across the country, including a University of Colorado School of Medicine faculty member, found that hospitals serving children may face financial penalties for patient readmissions due to factors beyond the control of the hospital.

15 Feb 2016

Researchers report first-ever link between noradrenergic neurons and vulnerability to depression

The team of Bruno Giros, a researcher at the Douglas Mental Health University Institute and professor of psychiatry at McGill University, reports the first-ever connection between noradrenergic neurons and vulnerability to depression. Published in the journal Nature Neuroscience, this breakthrough paves the way for new depression treatments that target the adrenergic system.

15 Feb 2016

Survey: Some patients with multiple sclerosis not engaging with specialist services

A new survey has highlighted that the lack of engagement with specialist services of some patients with multiple sclerosis (MS) is a concern for MS-specialists.

15 Feb 2016

Medical Research News

Regrowing dopaminergic neurons may lead to new therapy for Parkinson's disease

Co-parenting a child has bigger impact on the immune system than flu vaccine or gastroenteritis

Study finds no beneficial effect of cancer medication on Alzheimer's disease

Study: Delirium, muscle weakness and other neurological complications of sepsis poorly understood

New study to evaluate use of whole umbilical cord blood to accelerate stroke recovery

Researchers identify how Toxoplasma parasite crosses blood-brain barrier

Scientists discover new subgroups of ILC immune cells using single-cell RNA sequencing

One specific microRNA has strong links to autism spectrum disorder, say TSRI scientists

CMV-based vaccine provides protection against Ebola virus

Variations in Tie2 gene play significant role in patient responses to infections

Unpaid caregivers more likely to experience emotional, physical and financial difficulties

Proof-of-concept data for NanoString's Hyb & Seq chemistry presented at AGBT Meeting

Research findings identify potential genetics-guided precision medicine for leukemia patients

St. Jude-led scientists explore better ways to use blood-forming stem cells for therapeutic interventions

Hereditary spastic paraplegia characteristics unveiled

Wake Forest Baptist scientists prove feasibility of printing living tissue structures for surgical implantation

Critical discovery holds key to explaining how 'good' gut bacteria promote health

Hospitals serving children may face financial penalties for readmissions, researchers find

Researchers report first-ever link between noradrenergic neurons and vulnerability to depression

Survey: Some patients with multiple sclerosis not engaging with specialist services

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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