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Cells communicate to their neighbors and compare notes before making a move

To decide whether and where to move in the body, cells must read chemical signals in their environment. Individual cells do not act alone during this process, two new studies on mouse mammary tissue show. Instead, the cells make decisions collectively after exchanging information about the chemical messages they are receiving.

22 Jan 2016

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Researchers have discovered gene-targets (biomarkers) that may enable alternative treatments or the potential design of new drugs that target metastasis-promoting tumor genes.

22 Jan 2016

Swedish research group publishes scientific discoveries concerning EKC in Acta Ophthalmologica journal

A Swedish research group at St. Erik Eye Hospital, Stockholm, Karolinska Institutet, Solna, and Umeå University has published scientific discoveries concerning the serious infectious eye disease EKC in the prestigious journal Acta Ophthalmologica.

22 Jan 2016

New study identifies DKK3 as a driver of kidney fibrosis

Chronic kidney disease can develop in response to a variety of insults and is characterized by progressive renal fibrosis and atrophy of kidney tubule. Therapeutic options are limited and the disease is often not detected until later stages.

22 Jan 2016

Blocking class II MHC molecules on graft endothelium limits acute rejection

A limitation of organ transplant is acute rejection of the graft by the host immune system. Graft rejection is mediated by the development of CD8+ cytotoxic T cells that target donor MHC class I molecules, and in animal models, these cells have been shown to develop in secondary lymphoid organs.

22 Jan 2016

Fibrosis in kidney transplants driven by continuous injury

Clinically, kidney fibrosis can be used to assess stage, progression, and prognosis for both kidney transplants and kidney disease. There is debate as to whether kidney fibrosis is a maladaptive, injury-triggered process that inherently progresses to kidney failure or an adaptive wound-healing process that stabilizes the injury site.

22 Jan 2016

New brain imaging technique may help identify children at risk of developing depression

A new brain imaging study from MIT and Harvard Medical School may lead to a screen that could identify children at high risk of developing depression later in life.

22 Jan 2016

People suffering from chronic stress, anxiety may be at increased risk for depression and dementia

A scientific review paper warns that people need to find ways to reduce chronic stress and anxiety in their lives or they may be at increased risk for developing depression and even dementia.

22 Jan 2016

New machine-learning technique could be used to uncover previously unknown features of organisms

A powerful new machine-learning technique can be applied to large datasets in the biological sciences to uncover previously unknown features of organisms and their genes, according to a team led by researchers from the Perelman School of Medicine at the University of Pennsylvania.

22 Jan 2016

Mindfulness could help children avoid obesity

Mindfulness, described as paying attention on purpose and being in the present moment with acceptance, could be an effective way to help children avoid obesity. New research published in the journal Heliyon suggests that the balance in brain networks in children who are obese is different compared to healthy-weight children, making them more prone to over-eating.

22 Jan 2016

Parental debt may have adverse effects on socioemotional well-being of children

Certain types of debt that parents take on may have adverse effects on children's socioemotional well-being according to a new study by researchers at the University of Wisconsin at Madison and Dartmouth published by the journal Pediatrics.

22 Jan 2016

Champions Oncology begins prospective correlative trial of PDX in patients with sarcoma

Champions Oncology today announced that it has initiated a sponsored prospective correlative trial of patient derived xenograft modeling (PDX or Champions TumorGraft PDX models) in patients with metastatic or recurrent sarcoma. Mount Sinai Hospital in Toronto, Canada is the first clinical site to enroll patients in the newly-opened study.

21 Jan 2016

Oxeia accelerating development of neurometabolic treatments for concussions

Oxeia Biopharmaceuticals, Inc., a biotechnology company, is catalyzing the development of first-in-class neurometabolic treatments for concussions and other aspects of brain injury.

21 Jan 2016

MD Anderson and AbbVie join forces to design new immunotherapy cancer patients

The immunotherapy platform at The University of Texas MD Anderson Cancer Center and the global biopharmaceutical company AbbVie will join forces to find new ways to unleash the immune system's potential to fight cancer.

21 Jan 2016

Migraines heat up as women near menopause

Migraine headaches heat up as women approach menopause, according to a new study from researchers at the University of Cincinnati, Montefiore Headache Center, Albert Einstein College of Medicine and Vedanta Research.

21 Jan 2016

Parental support programmes could promote healthy eating behaviours in obese children

Parental support programmes in areas with the greatest needs can have a positive effect on the consumption of unhealthy food and drink and on weight increases in obese children. This according to a randomised study conducted by Karolinska Institutet and the Stockholm County Council, Sweden, published in the International Journal of Behavioural Nutrition and Physical Activity.

21 Jan 2016

Findings may explain why type 2 diabetic patients experience smelling problems

In a study in type 2 diabetic rats, researchers at the Karolinska Institutet have identified alterations in specific nerve cells that are important for odor identification. The findings might explain why type 2 diabetic patients often experience smelling problems and potentially open up a new research field to develop preventive therapies against neurodegenerative diseases in type 2 diabetic patients.

21 Jan 2016

Psychological techniques help reduce body dissatisfaction in women with bulimia nervosa

Researchers from the University of Granada have proven that there are two psychological techniques that help reducing body dissatisfaction and its associated symptoms in women with bulimia nervosa, both of them based in the exposure of their bodies in a mirror.

21 Jan 2016

Research sheds light on mechanism by which hemangioblasts become blood cells

A research group led by Lecturer Makoto Kobayashi of the University of Tsukuba Faculty of Medicine, has managed to shed light on the puzzling mechanism by which hemangioblasts become blood cells. Although hemangioblasts are the common precursor cells for blood cells and vascular endothelia that are present during the fetal period, the discovery of hemangioblasts in adult organisms has begun to garner attention from the medical world.

21 Jan 2016

Childhood abuse and neglect associated with worse executive function in adulthood

The scars of childhood abuse and neglect affect adults' brains for decades to come - including their ability to process and act on information both quickly and accurately, new research suggests.

21 Jan 2016

Medical Research News

Cells communicate to their neighbors and compare notes before making a move

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Swedish research group publishes scientific discoveries concerning EKC in Acta Ophthalmologica journal

New study identifies DKK3 as a driver of kidney fibrosis

Blocking class II MHC molecules on graft endothelium limits acute rejection

Fibrosis in kidney transplants driven by continuous injury

New brain imaging technique may help identify children at risk of developing depression

People suffering from chronic stress, anxiety may be at increased risk for depression and dementia

New machine-learning technique could be used to uncover previously unknown features of organisms

Mindfulness could help children avoid obesity

Parental debt may have adverse effects on socioemotional well-being of children

Champions Oncology begins prospective correlative trial of PDX in patients with sarcoma

Oxeia accelerating development of neurometabolic treatments for concussions

MD Anderson and AbbVie join forces to design new immunotherapy cancer patients

Migraines heat up as women near menopause

Parental support programmes could promote healthy eating behaviours in obese children

Findings may explain why type 2 diabetic patients experience smelling problems

Psychological techniques help reduce body dissatisfaction in women with bulimia nervosa

Research sheds light on mechanism by which hemangioblasts become blood cells

Childhood abuse and neglect associated with worse executive function in adulthood

The CAR T Veteran: A Journey of Resilience, Remission, and Advocacy

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

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