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Children with Wilms tumour can now be given less intensive chemotherapy

CHILDREN with a rare type of cancer called Wilms' tumour who are at low risk of relapsing can now be given less intensive treatment, avoiding a type of chemotherapy that can cause irreversible heart problems in later life.

9 Jul 2015

MGH investigators report that medication could augment benefits of bariatric surgery

New findings about the mechanisms involved - or not involved - in the effects of the most common form of bariatric surgery suggest that combining surgery with a specific type of medication could augment the benefits of the procedure. In a report that has been published online in the journal Endocrinology, Massachusetts General Hospital investigators report that the effects of Roux-en-Y gastric bypass (RYGB) do not utilize neurologic pathways controlled by the serotonin 2C receptor.

9 Jul 2015

NSU cancer researcher selected for prestigious J. William Fulbright award

Nova Southeastern University cancer researcher Appu Rathinavelu, Ph.D., was selected for a prestigious J. William Fulbright award to conduct cancer research and training in India. Dr. Rathinavelu is associate dean for institutional planning and development at NSU's College of Pharmacy and executive director of NSU's Rumbaugh-Goodwin Institute for Cancer Research.

9 Jul 2015

Mayo Clinic awarded $11 million NCI grant to study survivorship in patients with non-Hodgkin lymphoma

Mayo Clinic announced today that it has received a five-year, $11 million grant from the National Cancer Institute to study survivorship in patients with non-Hodgkin lymphoma (NHL). The Lymphoma Epidemiology of Outcomes Cohort Study will enroll 12,000 patients with NHL. The study will follow these patients for long-term prognosis and survivorship.

9 Jul 2015

Computer model shows how cancerous tumors manipulate blood-vessel growth for their own benefit

Rice University researchers have built a simulation to show how cancerous tumors manipulate blood-vessel growth for their own benefit.

9 Jul 2015

Annual financial impact of smoking on California's economy tallied at $18.1 billion

Today Nicotine & Tobacco Research publishes the third in a series of studies on the cost of smoking in California, one of the first US states to implement a comprehensive tobacco control program.

9 Jul 2015

Faster weight gain during inpatient treatment safe, effective for anorexia patients

A new study led by Johns Hopkins Medicine researchers of patients hospitalized with anorexia nervosa shows that a faster weight gain during inpatient treatment — well beyond what national standards recommend — is safe and effective.

9 Jul 2015

Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

According to a new series of studies out of NYU Langone Medical Center, two chemicals increasingly used during manufacturing to strengthen plastic wrap, soap, cosmetics, and processed food containers have been linked to a rise in risk of high blood pressure and diabetes in children and adolescents.

9 Jul 2015

International research team identifies new gene associated with 4H leukodystrophy

Leukodystrophies are deadly neurodegenerative diseases that affect one in 7,000 children and remain incurable. These genetic diseases attack myelin or the "insulating rubber sheath" surrounding neurons, which leads to deteriorating health for affected children.

9 Jul 2015

UK study suggests new approach to develop highly-potent drugs

A new study led by University of Kentucky researchers suggests a new approach to develop highly-potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer as well as viral and bacterial infections.

9 Jul 2015

Internet-based program can help people manage their chronic pain, reduce reliance on opioids

Washington State University researchers have found that people can manage chronic pain and reduce their reliance on opioids through an Internet-based program that teaches non-medical alternatives like increased physical activity, thinking more positively and dealing with emotions.

8 Jul 2015

New research identifies potential treatment for primary effusion lymphoma

New research from the University of Southern California Norris Comprehensive Cancer Center has identified a potential treatment for a rare but previously incurable form of lymphoma that is observed primarily in patients with HIV/AIDS infection.

8 Jul 2015

LUX-Lung 8 supports afatinib in squamous NSCLC

Compared with erlotinib, treatment with afatinib leads to outcomes in previously treated patients with advanced squamous non-small-cell lung cancer, suggest the results of a head-to-head trial.

8 Jul 2015

Surgery delays for elderly patients with traumatic spinal cord injury

Older patients with traumatic spinal cord injury experience significant delays in being transferred to a specialist treatment centre and receiving surgery, compared with younger patients, study findings show.

8 Jul 2015

DME treatment evolves in favour of intravitreal anti-VEGF injections

Treatment strategies for diabetic macular oedema have evolved over the past decade, with focal laser therapy being largely replaced by intravitreal injections, an observational case series of more than 1500 patients shows.

8 Jul 2015

Retinal function, structure changes in proliferative diabetic retinopathy revealed

Patients with proliferative diabetic retinopathy exhibit marked visual dysfunction and structural changes in both the inner and outer retinal layers, research findings indicate.

8 Jul 2015

Macular atrophy predicts vision in ranibizumab-treated exudative AMD patients

Progression and severity of macular atrophy are the main anatomical determinants of long-term visual outcomes in exudative age-related macular degeneration patients treated with ranibizumab, suggest SEVEN-UP study results.

8 Jul 2015

Darapladib shows promise in diabetic macular oedema

Placebo-controlled trial findings show that lipoprotein-associated phospholipase A2 inhibition modestly benefits the vision of patients with centre-involved diabetic macular oedema and warrants further investigation.

8 Jul 2015

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

Natural killer cells of the immune system can fend off malignant lymphoma cells and thus are considered a promising therapeutic approach. However, in the direct vicinity of the tumor they lose their effect.

8 Jul 2015

Study aims to determine utility of Trovagene's PCM technology for predicting response to cancer immunotherapy

Trovagene, Inc., a developer of cell-free molecular diagnostics, today announced the launch of a study that aims to determine utility of the Company's Precision Cancer Monitoring (PCM) technology for predicting response to treatment in advanced melanoma patients receiving one or a combination of the novel immunotherapy agents Yervoy (ipilumumab), a CTLA-4 inhibitor, and Opdivo (nivolumab), a PD-1 inhibitor.

8 Jul 2015

Medical Research News

Children with Wilms tumour can now be given less intensive chemotherapy

MGH investigators report that medication could augment benefits of bariatric surgery

NSU cancer researcher selected for prestigious J. William Fulbright award

Mayo Clinic awarded $11 million NCI grant to study survivorship in patients with non-Hodgkin lymphoma

Computer model shows how cancerous tumors manipulate blood-vessel growth for their own benefit

Annual financial impact of smoking on California's economy tallied at $18.1 billion

Faster weight gain during inpatient treatment safe, effective for anorexia patients

Chemicals used in plastics linked to increased risk of high blood pressure, diabetes in children and adolescents

International research team identifies new gene associated with 4H leukodystrophy

UK study suggests new approach to develop highly-potent drugs

Internet-based program can help people manage their chronic pain, reduce reliance on opioids

New research identifies potential treatment for primary effusion lymphoma

LUX-Lung 8 supports afatinib in squamous NSCLC

Surgery delays for elderly patients with traumatic spinal cord injury

DME treatment evolves in favour of intravitreal anti-VEGF injections

Retinal function, structure changes in proliferative diabetic retinopathy revealed

Macular atrophy predicts vision in ranibizumab-treated exudative AMD patients

Darapladib shows promise in diabetic macular oedema

Scientists elucidate which mechanisms block natural killer cells and how this could be lifted

Study aims to determine utility of Trovagene's PCM technology for predicting response to cancer immunotherapy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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