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Research focuses on understanding racial, ethnic disparities in colon cancer outcomes

Blase Polite, MD, has expertise in the treatment of gastrointestinal malignancies, with a particular focus on colon, rectal, and anal cancers, and neuroendocrine (carcinoid) tumors.

27 Oct 2015

Study: Green office environments influence cognitive function performance of workers

People who work in well-ventilated offices with below-average levels of indoor pollutants and carbon dioxide (CO2) have significantly higher cognitive functioning scores--in crucial areas such as responding to a crisis or developing strategy--than those who work in offices with typical levels, according to a new study from the Harvard T.H. Chan School of Public Health's Center for Health and the Global Environment, SUNY Upstate Medical University, and Syracuse University.

27 Oct 2015

Scientists present alternative method for using significant variables to make useful predictions

Scientists at Columbia University, the University of California, San Diego (UCSD) and Harvard University have presented an alternative method to address the challenge of using significant variables to make useful predictions in areas such as complex disease.

27 Oct 2015

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Four tiny segments of RNA appear to play critical roles in controlling cholesterol and triglyceride metabolism. In their report receiving advance online publication in Nature Medicine, a Massachusetts General Hospital-based research team describes finding how these microRNAs could reduce the expression of proteins playing key roles in the generation of beneficial HDL cholesterol, the disposal of artery-clogging LDL cholesterol, control of triglyceride levels and other risk factors of cardiovascular disease.

27 Oct 2015

Researchers develop multiplexed screening approach to study cancer development in mice

In a novel use of the CRISPR/Cas9 system, which can be deployed to switch genes off, researchers from Germany, the UK and Spain have developed a multiplexed screening approach to study and model cancer development in mice. The scientists mutated genes in the adult mouse liver uncovering their cancer-causing roles and determining which combinations of genes cooperate to cause liver cancer.

27 Oct 2015

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Washington State University researchers have developed a unique, tiny protein cage to deliver nasty chemotherapy chemicals directly to cancer cells. Direct delivery could improve treatment and lessen what can be horrendous side effects from toxic drugs.

27 Oct 2015

Many young women not receiving adequate counseling on heart disease

Only half of younger heart attack patients believed that they were at risk before the onset of an attack, and even fewer discussed health risks with their doctors, according to Yale School of Public Health researchers. The findings were more pronounced among women than men.

27 Oct 2015

Maintaining normal BMI after pregnancy can help prevent pelvic organ prolapse

Maintaining a normal body mass index (BMI) is important for good cardiovascular health and blood sugar control, but maintaining it after pregnancy can also be key to preventing pelvic organ prolapse, according to a new study by Yale School of Medicine researchers.

27 Oct 2015

Replacing animal-derived antibodies with modern technologies can improve quality of research, reduce costs

Time, money, and tens of thousands of animals could be saved if researchers replace animal-derived antibodies with modern technologies, according to a review by the PETA International Science Consortium Ltd. published today in Biotechnology Advances, a peer-reviewed journal covering developments and trends in biotechnology principles and applications.

27 Oct 2015

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Medical professionals know that when a spouse dies, the surviving partner is at increased risk of suffering early mortality - but they don't entirely understand why. A new Rice University professor has received a $3.765 million R01 grant from the National Institutes of Health to embark on a five-year study of the connection between psychological and physiological responses to such extraordinary stress.

27 Oct 2015

Researchers pinpoint mechanisms that cause chemoresistance in ovarian cancer patients

Resistance to chemotherapy is a major problem for those suffering from ovarian cancer--a problem that prevents a cure from a disease dubbed the "silent killer." University of Georgia researchers are giving patients new hope with recent findings that help pinpoint the mechanisms causing chemoresistance.

27 Oct 2015

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Massachusetts General Hospital investigators have discovered a mechanism behind the spread of neurofibrillary tangles - one of the two hallmarks of Alzheimer's disease - through the brains of affected individuals.

27 Oct 2015

Scientists decode central signal switch associated with epileptic seizures

Scientists at the University of Bonn and the Hebrew University of Jerusalem (Israel) have decoded a central signal cascade associated with epileptic seizures. If the researchers blocked a central switch in epileptic mice, the frequency and severity of the seizures decreased. Using a novel technology, it was possible to observe the processes prior to the occurrence of epileptic seizures in living animals.

27 Oct 2015

Genetic discovery sheds light on how prostate cancer develops and spreads

A new and important genetic discovery, which sheds light on how prostate cancers develop and spread, has been made by an international research team led by scientists at The University of Nottingham.

27 Oct 2015

Limited use of general anesthesia does not cause developmental problems for children

An international team of researchers that includes a pediatric anesthesiologist from the University of Colorado School of Medicine and Children's Hospital Colorado is reporting that limited use of general anesthesia with an infant does not cause developmental problems for the child.

27 Oct 2015

Expectant mothers need to avoid certain cosmetics, cleaning agents and medicines during first trimester

Expectant mothers in their first trimester should avoid certain cosmetics, cleaning agents and medicines, to protect the developing fetal brain from chemicals that can trigger autism, York U health researchers have found.

27 Oct 2015

UTMB researchers find mechanisms to determine when pregnant women go into labor

During the last few weeks of a woman's pregnancy, many keep an overnight bag ready to go at a moment's notice in case they begin to go into labor. They do this because there is no clear signal that labor is about to begin - before the body makes it abundantly clear that this process has started. Understanding the mechanisms that initiate this process is especially important when treating women at risk of going into labor early.

27 Oct 2015

New article reviews latest advances in magnetic particle tracking in cell therapy

A new article published in Regenerative Medicine reviews the latest advances in magnetic particle tracking in cell therapy, a potentially groundbreaking strategy in disease treatment and regenerative medicine.

27 Oct 2015

Study: Reduction in Amazon deforestation improves air quality, prevents premature deaths

Because of decreasing deforestation and emissions from forest fires in the Amazon over the past ten years, the amount of particulate matter (aerosols), ozone, carbon monoxide, nitrogen oxide and other atmospheric pollutants released by burning biomass has fallen by 30% on average during the dry season in southern Brazil, Paraguay, northern Bolivia and Argentina.

27 Oct 2015

New drug combination may be effective against malignant melanoma

A team of Massachusetts General Hospital investigators has discovered a new combination of drugs that may be effective against one of the deadliest cancers, malignant melanoma. The combination - pairing a drug targeted against mutations in the BRAF gene with a second drug that targets another important signaling pathway - was discovered through one of the largest screens of cancer drug combinations conducted to date.

27 Oct 2015

Medical Research News

Research focuses on understanding racial, ethnic disparities in colon cancer outcomes

Study: Green office environments influence cognitive function performance of workers

Scientists present alternative method for using significant variables to make useful predictions

Four microRNAs appear to play critical roles in controlling cholesterol, triglyceride metabolism

Researchers develop multiplexed screening approach to study cancer development in mice

Unique, tiny protein cage developed to deliver chemotherapy chemicals directly to cancer cells

Many young women not receiving adequate counseling on heart disease

Maintaining normal BMI after pregnancy can help prevent pelvic organ prolapse

Replacing animal-derived antibodies with modern technologies can improve quality of research, reduce costs

New Rice University study explores connections between fatal bereavement and cardiovascular risk

Researchers pinpoint mechanisms that cause chemoresistance in ovarian cancer patients

MGH researchers identify mechanism behind the spread of neurofibrillary tangles

Scientists decode central signal switch associated with epileptic seizures

Genetic discovery sheds light on how prostate cancer develops and spreads

Limited use of general anesthesia does not cause developmental problems for children

Expectant mothers need to avoid certain cosmetics, cleaning agents and medicines during first trimester

UTMB researchers find mechanisms to determine when pregnant women go into labor

New article reviews latest advances in magnetic particle tracking in cell therapy

Study: Reduction in Amazon deforestation improves air quality, prevents premature deaths

New drug combination may be effective against malignant melanoma

Innovating for impact: Jordi Labs on aligning methodologies with FDA expectation

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

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