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Novel mechanism may help explain the virulence of 1918 'Spanish' flu

While yearly outbreaks of flu kill about 250,000 to 500,000 people worldwide, the 1918 "Spanish" flu infected one-third of the world's population and killed 50 million to 100 million. Chad Petit, Ph.D., assistant professor in the University of Alabama at Birmingham Department of Biochemistry and Molecular Genetics, has discovered a novel mechanism for one 1918 flu virus protein that may help explain the virulence of that unusually deadly pandemic.

23 Sep 2015

TTUHSC El Paso researcher awarded $375,000 grant to develop genetically altered TB vaccines

A $375,000 grant from the Robert J. Kleberg Jr. and Helen C. Kleberg Foundation was awarded to Subramanian Dhandayuthapani, Ph.D., an associate professor in the Center of Emphasis in Infectious Diseases at the Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, to develop genetically altered vaccines against tuberculosis (TB).

23 Sep 2015

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

Working with tissue, blood and DNA from six people with precancerous and cancerous lung lesions, a team of Johns Hopkins scientists has identified what it believes are among the very earliest “premalignant” genetic changes that mark the potential onset of the most common and deadliest form of disease.

23 Sep 2015

TSRI study reveals key morphine regulator that may help develop less-addictive pain medications

Once used in the 18th century as currency to reverse the trade imbalance between China and Britain, opiates that contain morphine have been misunderstood almost continually ever since.

23 Sep 2015

IUPUI awarded grant to develop breathalyzer-type device for detecting hypoglycemia in diabetes people

A multidisciplinary team of researchers at Indiana University-Purdue University Indianapolis has been awarded a $738,000 National Science Foundation grant to develop a breathalyzer-type device to detect the onset of hypoglycemia, or low blood sugar episodes, in people with diabetes.

23 Sep 2015

New, FDA-approved device provides minimally invasive approach to chronic GERD

Approximately 20 million Americans will experience some type of gastroesophageal reflux disease, or GERD, in their lives. In some cases, patients suffer resulting heart burn or acid regurgitation so severe that they require surgery to repair damage to their esophagus.

23 Sep 2015

Fidgeting movements may counteract adverse health impacts of sitting for long periods

New research suggests that the movements involved in fidgeting may counteract the adverse health impacts of sitting for long periods.

23 Sep 2015

Healthy adults with larger orbitofrontal cortex are more optimistic, less anxious

A new study links anxiety, a brain structure called the orbitofrontal cortex, and optimism, finding that healthy adults who have larger OFCs tend to be more optimistic and less anxious.

23 Sep 2015

Reduced conflict-related brain activity linked to higher risk for psychosis

Researchers led by Bradley S. Peterson, MD, director of the Institute for the Developing Mind at Children's Hospital Los Angeles, have shown that lower levels of conflict-related brain activity are associated with a higher risk for later psychosis.

23 Sep 2015

Subtle differences in brain function make women react differently to negative emotions, shows research

Women react differently to negative images compared to men, which may be explained by subtle differences in brain function.

23 Sep 2015

Older pneumonia patients can benefit from ICU admission

When an older person gets hospitalized for pneumonia, where's the best place to care for them? New research findings about deaths and health care costs in such patients fly in the face of conventional wisdom - and could change where doctors decide to treat them.

23 Sep 2015

FAU researcher finds unique way to monitor sickle cell disease

A researcher from Florida Atlantic University has come up with a unique way to monitor sickle cell disease -- a serious blood disorder -- using a smart phone. With a $166,935 grant from the National Science Foundation, E. (Sarah) Du, Ph.D., assistant professor in the Department of Ocean and Mechanical Engineering in FAU's College of Engineering and Computer Science, and principal investigator, will develop a portable smart sensor and a phone application for patients to analyze and store the results of their blood tests on a smart phone.

23 Sep 2015

University of Adelaide study sheds light on the activity of cancer-suppressing gene

University of Adelaide researchers have uncovered the role played by a gene which suppresses the development of cancer. The findings, published in the journal PLOS ONE, open new opportunities for scientists to find treatments for cancer.

23 Sep 2015

Novel graphene oxide-based biosensor may speed up development of new drugs against HIV, cancer

Longing to find a cure for cancer, HIV and other yet incurable diseases, researchers have already tried out hundreds of drugs, each requiring preclinical and clinical testing with live subjects. How many chemical agents more to try? Moving at such rate, will we find the cure during our lifetime? One of the easiest ways to speed up the drug development process is to simply perform it outside of the living body (e.g., by watching the substances react with the smallest pieces of live tissue and thus quickly predicting the overall effect it will make to the body when inside).

23 Sep 2015

Study demonstrates potential of FCPCs as new source for cartilage regeneration

The self-repair of injured cartilage is difficult for several reasons, foremost of which is the lack of blood supply to the tissue. Therapeutic efforts aimed at cartilage repair are often not optimal. Surgical repair techniques often lead to the formation of fibrocartilage, which is weaker and less durable. Although cell transplantation aimed at cartilage repair has been carried out using mesenchymal stem cells (MSCs), varying outcomes have resulted, despite the propensity of MSCs to proliferate and differentiate.

23 Sep 2015

Researchers receive $13 million NIH grant to develop new stem cell-based assays for studying autism

The National Institutes of Health has awarded a $13 million grant over five years to develop and disseminate new stem cell-based technologies and assays for studying autism spectrum disorder (ASD) and other mental health diseases to a consortium of researchers at the University of California, San Diego and the Salk Institute for Biological Studies, working in tandem with leaders in the biotechnology sector.

23 Sep 2015

Prashant Mahajan awarded $5.76 million grant to study how febrile infants can avoid invasive procedures

Prashant Mahajan, M.D., professor of Pediatrics and Emergency Medicine, chief of the Division of Emergency Medicine in the Department of Pediatrics at Wayne State University and Children's Hospital of Michigan, has been awarded a five-year, $5.76 million grant (1R01HD085233) by the Eunice Kennedy Shriver National Institute of Child Health & Human Development of the National Institutes of Health.

23 Sep 2015

Findings may suggest new therapeutic target to combat memory loss in aging, Alzheimer's disease

Northwestern Medicine scientists have examined activity in a little-studied part of the brain associated with memory and found for the first time the reason that neurons there become more active in old age, findings that may suggest a new target for future therapies to combat memory loss in aging and Alzheimer's disease.

23 Sep 2015

University of Alberta researchers discover diabetes 'dimmer' switch

Patrick MacDonald has dedicated much of his life to diabetes research. It's a job he knows is far too large and complex for any one person, but with his latest publication, he knows his work is playing a part.

23 Sep 2015

Amyloid PET method works well for detecting early signs of Alzheimer's disease

A method for detecting early signs of Alzheimer's disease using amyloid PET imaging works as well as the previously used cerebrospinal fluid sample method. This is the conclusion of a new Lund University study - the most thorough and extensive undertaken in the field so far.

23 Sep 2015

Medical Research News

Novel mechanism may help explain the virulence of 1918 'Spanish' flu

TTUHSC El Paso researcher awarded $375,000 grant to develop genetically altered TB vaccines

Johns Hopkins scientists discover earliest premalignant genetic changes that mark potential onset of lung cancer

TSRI study reveals key morphine regulator that may help develop less-addictive pain medications

IUPUI awarded grant to develop breathalyzer-type device for detecting hypoglycemia in diabetes people

New, FDA-approved device provides minimally invasive approach to chronic GERD

Fidgeting movements may counteract adverse health impacts of sitting for long periods

Healthy adults with larger orbitofrontal cortex are more optimistic, less anxious

Reduced conflict-related brain activity linked to higher risk for psychosis

Subtle differences in brain function make women react differently to negative emotions, shows research

Older pneumonia patients can benefit from ICU admission

FAU researcher finds unique way to monitor sickle cell disease

University of Adelaide study sheds light on the activity of cancer-suppressing gene

Novel graphene oxide-based biosensor may speed up development of new drugs against HIV, cancer

Study demonstrates potential of FCPCs as new source for cartilage regeneration

Researchers receive $13 million NIH grant to develop new stem cell-based assays for studying autism

Prashant Mahajan awarded $5.76 million grant to study how febrile infants can avoid invasive procedures

Findings may suggest new therapeutic target to combat memory loss in aging, Alzheimer's disease

University of Alberta researchers discover diabetes 'dimmer' switch

Amyloid PET method works well for detecting early signs of Alzheimer's disease

Exploring the role of confocal-based high-content imaging in advancing core facilities

Transforming Cardiovascular Care: Insights from Mina Makar at AstraZeneca

Clue's CEO Rhiannon White on the Future of Femtech and PCOS

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